research Role of Transepidermal and Transfollicular Routes in Percutaneous Absorption of Steroids: In vitro Studies on Human Skin
Hair follicles and glands significantly increase steroid absorption in skin.
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30 / 1000+ resultsresearch The risk of hydroquinone and sunscreen over-absorption via photodamaged skin is not greater in senescent skin as compared to young skin: Nude mouse as an animal model
Aging and sun damage do not increase the skin's absorption of certain sunscreens and drugs.
research Use of the skin sandwich technique to probe the role of the hair follicles in sonophoresis
Ultrasound increases skin permeability but blocks hair follicles.
research Coumarin derivatives, but not coumarin itself, cause skin irritation via topical delivery
Coumarin derivatives cause skin irritation, but coumarin itself does not.
research Impact of Ester Promoieties on Transdermal Delivery of Ketorolac
Balancing lipophilicity and solubility is key for effective and safe ketorolac prodrugs.
research Clinical Snippets
Topical Imiquimod may fight vascular tumors by affecting blood vessels or the immune system, low iron might be linked to some hair loss, removing the top skin layer helps vitamin C get in, genetic testing helps diagnose skin conditions, and too much iron could worsen skin inflammation.
research Fabrication of polyvinyl pyrrolidone-K90/Eudragit RL100-based dissolving microneedle patches loaded with alpha-arbutin and resveratrol for skin depigmentation
Microneedle patches with alpha-arbutin and resveratrol can effectively reduce skin pigmentation without irritation.
research Systematic characterization of the barrier function of diverse ex vivo models of damaged human skin
Damaged skin has a weakened barrier, making it more vulnerable to substances and inflammation.
research The role of tight junctions in skin barrier function and dermal absorption
Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.
research Transepidermal UV radiation of scalp skin ex vivo induces hair follicle damage that is alleviated by the topical treatment with caffeine
Caffeine applied to the scalp can protect hair follicles from UV damage.
research Influence of tretinoin on the percutaneous absorption of minoxidil from an aqueous topical solution
Tretinoin cream boosts minoxidil absorption, possibly improving hair loss treatment.
research Microneedling dilates the follicular infundibulum and increases transfollicular absorption of liposomal sepia melanin
Microneedling helps increase the absorption of a melanin product into hair follicles, which may improve laser hair removal effectiveness.
research Potential of Nanoparticles as Permeation Enhancers and Targeted Delivery Options for Skin: Advantages and Disadvantages
Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.
research Fullerene nanoparticle in dermatological and cosmetic applications
Fullerenes show potential in skin care but need more safety research.
research Liposomal systems as drug delivery vehicles for dermal and transdermal applications
Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.
research Hair follicles contribute significantly to penetration through human skin only at times soon after application as a solvent deposited solid in man
Hair follicles greatly increase caffeine absorption through the skin shortly after it's applied.
research Stratum corneum dysfunction in dandruff
Improving skin barrier and using antifungal treatments can help manage dandruff.
research Effect of physical stimuli on hair follicle deposition of clobetasol-loaded Lipid Nanocarriers
NLCs with manual massage greatly improve clobetasol delivery to hair follicles.
research An investigation of in vivo wound healing activity of biologically synthesized silver nanoparticles
Silver nanoparticles in gel form can effectively heal wounds.
research Methods for quantifying intrafollicular drug delivery: a critical appraisal
The document concludes that there is no agreed-upon best method for measuring drug delivery within hair follicles and more research is needed to validate current techniques.
research Topical Formulations Containing Finasteride. Part I: In Vitro Permeation/Penetration Study and In Vivo Pharmacokinetics in Hairless Rat
Finasteride cream helps hair growth with less side effects.
research Exogenous and endogenous lipids of human hair
Removing external lipids from hair reduces moisture and increases strength, while removing internal lipids decreases water permeability.
research Non-invasive Approaches for the Diagnosis of Autoimmune/Autoinflammatory Skin Diseases—A Focus on Psoriasis and Lupus erythematosus
Non-invasive methods show promise for diagnosing skin diseases like psoriasis and lupus but need more research for regular use.
research (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile, a potent androgen receptor antagonist for stimulating hair growth and reducing sebum production
The compound (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile can stimulate hair growth and reduce oil production when applied topically.
research Nanocarrier Systems for Transdermal Drug Delivery
Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.
research Circadian rhythms on skin function of hairless rats: light and thermic influences
Light and temperature affect the daily skin function rhythms in hairless rats, with temperature influencing water loss but not skin hydration.
research Penetration and Distribution in Human Skin Focusing on the Hair Follicle
Targeting drugs to hair follicles can treat skin conditions, but reaching deep follicle areas is hard and needs more research.
research Trans-Epidermal Elimination Due to Insulin Formulation: Report of a Rare Adverse Effect
Switching insulin brands caused skin lesions in a diabetic woman, resolved by changing to oral medication.
research Nanostructured lipid carriers promote percutaneous absorption and hair follicle targeting of tofacitinib for treating alopecia areata
Nanostructured lipid carriers effectively deliver tofacitinib to hair follicles, reversing hair loss in alopecia areata.
research V Congress of the Portuguese Society of Cosmetological Sciences - Proceedings
The congress showed advancements in skin hydration, barrier function, and safe, effective new cosmetic formulations.