research Physical methods for topical skin drug delivery: concepts and applications
New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.
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research Omega 3 fatty acid-enriched nanoemulsion of thiocolchicoside for transdermal delivery: formulation, characterization and absorption studies
The new formulation improved the skin absorption of the drug Thiocolchicoside.
research Morphological characteristics and notes of the skin in preclinical toxicity assessment
Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.
research The Role of Paracellular Transport in the Intestinal Absorption and Biopharmaceutical Characterization of Minoxidil
research Intradermal and follicular delivery of adapalene liposomes
Liposomal adapalene improves delivery to hair follicles and reduces side effects for acne treatment.
research Follicular penetration of nano-sized particulate FA-PLGA and the dye RhBITC in dorsal dog and rat skin, and porcine ear skin as an in vitro model for the human integument
Hair follicles can effectively absorb nano-sized particles, making them potential targets for localized drug delivery.
research Permeation of topically applied caffeine through human skin – a comparison of in vivo and in vitro data
Caffeine penetrates human skin in lab tests similarly to real-life conditions, but actual skin use is still essential for accurate results.
research THE ENTRY OF CA45 INTO THE SKIN AND OTHER SOFT TISSUES OF THE RAT: AN AUTORADIOGRAPHIC AND SPODOGRAPHIC STUDY
Ca 45 mainly enters rat skin and eye through biosynthesis and may be adsorbed in cartilage and glands.
research A mechanism for topical cutaneous calcinosis
Epilation and DHT cause skin calcification by increasing ATP and calcium deposits.
research The Fate of Epidermal Tight Junctions in the stratum corneum: Their Involvement in the Regulation of Desquamation and Phenotypic Expression of Certain Skin Conditions
Tight junctions help control skin shedding and may be targets for treating certain skin conditions.
research Comparison of stratum corneum penetration and localization of a lipophilic model drug applied in an o/w microemulsion and an amphiphilic cream
The microemulsion delivered the dye deeper into the skin than the cream.
research Principles and clinical applications of transcutaneous laser-assisted drug delivery: A narrative review
Laser-assisted drug delivery can improve treatment for difficult skin conditions by enhancing drug absorption.
research Subacute cutaneous lupus erythematosus presenting as erythroderma
A woman with subacute cutaneous lupus erythematosus had widespread skin symptoms triggered by medication and sunlight, which improved with specific treatments.
research Epidermis reconstructed from the outer root sheath of human hair follicle. Effect of retinoic acid
Human hair follicles can be used to create skin-like tissue for wound healing and drug testing.
research Effect of Various Herbal and Chemical Enhancers on Skin Permeability to Cetirizine: A Study of Changes in Rat Skin Cells
Eucalyptus and Tween 80 most effectively increase cetirizine skin absorption.
research The Role of Paracellular Transport in the Intestinal Absorption and Biopharmaceutical Characterization of Minoxidil
Minoxidil's absorption is too variable for it to be a reliable reference drug.
research Penetration and Distribution in Human Skin Focusing on the Hair Follicle
Topical drugs can target hair follicles to treat skin conditions more effectively.
research Transfollicular drug delivery—Is it a reality?
Hair follicles may soon be used more for targeted and systemic drug delivery.
research The penetration, efficacy and potential of antiseptic nanoparticle-emulsions
Antiseptic nanoparticle-emulsions may improve skin disinfection by targeting hair follicles.
research Skin permeation of curcumin nanocrystals: Effect of particle size, delivery vehicles, and permeation enhancer
Smaller curcumin nanocrystals penetrate skin better, but additives and particle size affect absorption and accumulation.
research "A Critical Review: Recent Advances in Ethosomal Gel for Transdermal Drug Delivery Systems''
Ethosomal gels improve drug delivery through the skin, enhancing treatment effectiveness.
research Investigation of Follicular and Non-follicular Pathways for Polyarginine and Oleic Acid-Modified Nanoparticles
Surface-modified nanoparticles mainly use non-follicular pathways to enhance skin permeation of ibuprofen and could improve treatment for inflammatory skin diseases.
research Selective delivery of adapalene to the human hair follicle under finite dose conditions using polymeric micelle nanocarriers
Polymeric micelle nanocarriers deliver adapalene more effectively to hair follicles than commercial products.
research Advances in Nanocarrier Systems for Dermatologic Transdermal Drug Delivery: A Chemical and Molecular Review
Nanocarriers show promise for improving skin drug delivery in treating skin conditions.
research FORMULATION OF TOPICAL FINASTERIDE AND EVALUATION OF ITS PERCUTANEOUS ABSORPTION
research Microneedles as transdermal drug delivery system for enhancing skin disease treatment
Microneedles can improve skin disease treatment by delivering drugs directly through the skin.
research Interrogating the integument: the role of the epidermis in hair induction
The epidermis is crucial for hair growth.
research Microemulsions as a Surrogate Carrier for Dermal Drug Delivery
Microemulsions can effectively deliver drugs through the skin but require careful ingredient selection to avoid irritation.
research "A Critical Review: Recent Advances in Ethosomal Gel for Transdermal Drug Delivery Systems''
Ethosomal gels improve drug delivery through the skin, enhancing treatment effectiveness.
research Microneedles as a perspective for transdermal therapeutic systems
Microneedles could make it easier and less painful to deliver more types of drugs through the skin.