Search

for
Search:

Did you mean Transforming Growth Factor?

GlossaryTransforming Growth Factor

proteins regulating cell growth, differentiation, and immune responses

Transforming Growth Factor (TGF) refers to a group of proteins that play crucial roles in regulating cell growth, differentiation, and immune responses. There are two main types, TGF-α and TGF-β, with TGF-β being particularly important in processes like wound healing, fibrosis, and the regulation of the immune system. These factors are significant in both normal physiological processes and in the development of diseases such as cancer and fibrosis.

Related Terms

Sort by

Research

30 / 1000+ results

Differential Effects of Caffeine on Hair Shaft Elongation, Matrix and Outer Root Sheath Keratinocyte Proliferation, and Transforming Growth Factor-β2/Insulin-Like Growth Factor-1-Mediated Regulation of the Hair Cycle in Male and Female Human Hair Follicles In Vitro

research Differential effects of caffeine on hair shaft elongation, matrix and outer root sheath keratinocyte proliferation, and transforming growth factor‐β2/insulin‐like growth factor‐1‐mediated regulation of the hair cycle in male and female human hair folliclesin vitro

60 citations , May 2014 in “British Journal of Dermatology”

Caffeine affects hair growth and health differently in men and women.

Growth Differentiation Factor 11 (GDF11)/Transforming Growth Factor-β (TGF-β)/Mesenchymal Stem Cells (MSCs) Balance: A Complex Partnership in Skin Rejuvenation

research Growth Differentiation Factor 11 (GDF11)/Transforming Growth Factor - β (TGF - β)/Mesenchymal Stem Cells (MSCs) Balance: A Complicated Partnership in Skin Rejuvenation

1 citations , January 2019 in “Journal of Embryology & Stem Cell Research”

MSCs help rejuvenate skin by promoting cell growth and reducing inflammation.

Induction of Transforming Growth Factor-Beta 1 by Androgen Is Mediated by Reactive Oxygen Species in Hair Follicle Dermal Papilla Cells

research Induction of transforming growth factor-beta 1 by androgen is mediated by reactive oxygen species in hair follicle dermal papilla cells

56 citations , September 2013 in “Journal of Biochemistry and Molecular Biology”

Androgens increase a growth factor in hair cells by creating reactive oxygen species, and antioxidants might help treat hair loss.

Comparison of Transforming Growth Factor-Beta 1 Levels in Platelet Rich Plasma Using Pure and Buffy Coat Methods in a Healthy Population

research Perbandingan Kadar Transforming Growth Factor-Beta 1 pada Platelet Rich Plasma dengan Metode Pure dan Buffy Coat pada Populasi Individu Sehat

August 2025 in “Intisari Sains Medis”

The buffy coat method yields higher TGF-β1 levels in PRP, especially in males.

Discovery of 7-Methoxy-6-[4-(4-Methyl-1,3-Thiazol-2-yl)-1H-Imidazol-5-yl]-1,3-Benzothiazole (TASP0382088): A Potent and Selective Transforming Growth Factor-β Type I Receptor Inhibitor as a Topical Drug for Alopecia

research Discovery of 7-Methoxy-6-[4-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-5-yl]-1,3-benzothiazole (TASP0382088): A Potent and Selective Transforming Growth Factor-β Type I Receptor Inhibitor as a Topical Drug for Alopecia

6 citations , January 2013 in “Chemical & pharmaceutical bulletin/Chemical and pharmaceutical bulletin”

A new compound shows promise as a topical treatment for hair loss.

research Expression of transforming growth factor-beta (TGF-beta 1) and insulin-like growth factor II (IGF-II) messenger RNA in the developing subcutaneous tissue (SQ) of the fetal pig.

11 citations , January 1992 in “PubMed”

TGF-beta 1 and IGF-II mRNA have specific patterns in pig subcutaneous tissue, affecting fat and muscle development.

research Expression of transforming growth factor-β_1 and tumor necrosis factor-α in mice with radiationinduced pulmonary injury

January 2010 in “Zhongguo xiandai yixue/Zhongguo xiandai yixue zazhi”

TGF-β1 and TNF-α contribute to lung damage after radiation.

research Alopesi areata hastalarında serum interferon-gama, tümör nekrozis faktör-alfa, interlökin-13, interlökin-17 ve transforming growth faktör-beta düzeylerinin değerlendirilmesi

January 2016

Atopy and altered T cell functions contribute to Alopecia Areata.

research Latent transforming growth factor beta-binding protein 1 (LTBP1): roles as a multifunctional extracellular matrix regulator in human disease. From molecular mechanisms to clinical translation prospects

March 2026 in “Folia Histochemica et Cytobiologica”

LTBP1 is a key regulator in diseases and a potential target for new treatments.

Transforming Growth Factor-Beta in Stem Cells and Tissue Homeostasis

research Transforming growth factor-β in stem cells and tissue homeostasis

245 citations , January 2018 in “Bone Research”

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

research P311 induces the transdifferentiation of epidermal stem cells to myofibroblast-like cells by stimulating transforming growth factor β1 expression

24 citations , December 2016 in “Stem Cell Research & Therapy”

P311 helps skin stem cells become myofibroblast-like cells, aiding wound healing.

Increased Expression of Nerve Growth Factor and Neurokinin-1 Alarm the Hair Loss in Females with Trichodynia

research Increased expression of nerve growth factor and neurokinin-1 alarm the hair loss in female with trichodynia

March 2012 in “Journal of The American Academy of Dermatology”

Higher levels of certain nerve-related proteins are linked to hair loss in women with scalp pain.

Transforming Growth Factor-β, Smad, and Collagen Expression Patterns in Fetal and Adult Keratinocytes

research Transforming Growth Factor-??, Smad, and Collagen Expression Patterns in Fetal and Adult Keratinocytes

16 citations , February 2007 in “Plastic and Reconstructive Surgery”

Keratinocytes show more TGF-β system activity and collagen production as they age, which might affect wound scarring.

research Effects of Epidermal Growth Factor and Transforming Growth Factor on Cultured Hair Follicle Cells from Human Scalp

January 1994 in “Skin research”

EGF and TGF-α help maintain hair cell cultures, but TGF-β1 stops their growth.

research Exogenous IGF-1 promotes hair growth by stimulating cell proliferation and down regulating TGF-β1 in C57BL/6 mice in vivo

53 citations , March 2014 in “Growth Hormone & IGF Research”

IGF-1 injections help mice grow more hair by increasing cell growth and blocking a hair growth inhibitor.

research miR-129-5p Participates in Hair Follicle Growth by Targeting HOXC13 in Rabbit

5 citations , April 2022 in “Genes”

miR-129-5p affects hair growth by targeting the HOXC13 gene.

Collagen Hydrolysate from Mozambique Tilapia Scales Improves Hair and Skin Health

research Collagen Hydrolysate from the Scales of Mozambique Tilapia (Oreochromis mossambicus) Improve Hair and Skin Health by Alleviating Oxidative Stress and Inflammation and Promoting Hair Growth and Extracellular Matrix Factors

2 citations , August 2023 in “Marine drugs”

Collagen from tilapia scales may improve hair and skin health by reducing stress and inflammation and encouraging hair growth.

research Sodium pentaborate pentahydrate promotes hair growth through the Wnt/β-catenin pathway and growth factors

2 citations , May 2022 in “Journal of trace elements in medicine and biology”

Sodium pentaborate pentahydrate can increase hair growth and improve hair quality at certain doses.

research A ‘hot’ new twist to hair biology – involvement of vanilloid receptor‐1 signaling in human hair growth control

2 citations , September 2004 in “Experimental Dermatology”

VR1 signaling can inhibit hair growth by affecting cell processes and increasing hair growth inhibitors.

Garlic Exosomes Promote Hair Growth Through the Wnt/Beta-Catenin Pathway and Growth Factors

research Garlic Exosomes Promote Hair Growth Through the Wnt/β-catenin Pathway and Growth Factors

July 2023 in “Cureus”

Garlic can help hair grow by activating certain growth pathways, and it works whether you eat it or apply it to your scalp.

research Additional file 1: Table S1. of An Asian traditional herbal complex containing Houttuynia cordata Thunb, Perilla frutescens Var. acuta and green tea stimulates hair growth in mice

January 2017 in “Figshare”

The herbal mix with Houttuynia cordata, Perilla frutescens, and green tea boosts hair growth in mice.

research Cytokines and growth factors influence hair growth in vitro. Possible implications for the pathogenesis and treatment of alopecia areata

91 citations , March 1996 in “Archives of Dermatological Research”

Certain cytokines and growth factors can inhibit hair growth and may affect alopecia areata.

research Growth factors specifically alter hair follicle cell proliferation and collagenolytic activity alone or in combination

56 citations , December 1990 in “Differentiation”

Growth factors can either promote or inhibit hair follicle cell growth and collagen breakdown.

research The Study of Growth Factors in Patients with Androgenic Alopecia

7 citations , September 2017 in “Biomedical and Pharmacology Journal”

Growth factors greatly affect hair loss, with different levels seen in men, women, younger patients, and at the start of the condition.

research The Role of the VEGF, KGF, EGF, and TGF-β1 Growth Factors in the Pathogenesis of Telogen Effluvium in Women

5 citations , March 2017 in “Biomedical and Pharmacology Journal”

Certain growth factors significantly affect hair loss in women with telogen effluvium.

Individual Variation in Balance Between Platelet-Secreted Growth Factors Causing Contradictory Effects on Hair Follicle Could Potentially Impact Response to PRP Therapy in Patients With Scalp Hair Loss

research 878 Individual variation in balance between platelet-secreted growth factors causing contradictory effects on hair follicle could potentially impact response to PRP therapy in patients with scalp hair loss

1 citations , April 2018 in “Journal of Investigative Dermatology”

People respond differently to hair loss treatment with PRP because of individual differences in growth factors from platelets.

research Concentrated growth factor therapy as cosmetic treatment in discoid lupus erythematosus

February 2024 in “Journal of dermatology”

CGF therapy may help hair regrowth and improve scars in DLE patients.

research Growth Factors and Cutaneous Pathology

August 2020 in “CRC Press eBooks”

Abnormal growth factors can cause hair and skin issues.

research The roles of hepatocyte growth factor family members in androgen-regulation of human hair growth. A comparison of the expression of hepatocyte growth factor family members, HGF and MSP, and their receptors, c-Met and RON, in isolated hair follicles from normal and androgenetic alopecia (balding) scalp.

January 2010

Balding hair follicles have reduced growth factors and increased inhibitory factors, suggesting new treatment paths for hair loss.

research Rat hair follicle growth in vitro

58 citations , December 1992 in “British Journal of Dermatology”

Rat hair follicles grow longer in vitro, but certain factors can inhibit this growth.