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research Skin-specific expression of a truncated E1a oncoprotein binding to p105-Rb leads to abnormal hair follicle maturation without increased epidermal proliferation.

30 citations , June 1993 in “The Journal of Cell Biology”

The oncoprotein causes abnormal hair growth without increasing skin cancer risk.

research Genetic Upregulation of Activated Protein C Mitigates Delayed Effects of Acute Radiation Exposure in the Mouse Plasma

1 citations , April 2024 in “Metabolites”

Activated protein C helps protect mice from long-term radiation damage.

research Genetic Upregulation of Activated Protein C Mitigates Delayed Effects of Acute Radiation Exposure in the Mouse Plasma

March 2024 in “Preprints.org”

Activated protein C helps protect mice from radiation damage.

research Decision letter: Type XVII collagen coordinates proliferation in the interfollicular epidermis

April 2017

Type XVII collagen may help prevent skin aging.

research Epidermal Growth Factor as a Biologic Switch in Hair Growth Cycle

94 citations , July 2003 in “Journal of biological chemistry/The Journal of biological chemistry”

EGF controls hair growth by regulating hair follicles' growth phases.

research Epidermal expression of the truncated prelamin A causing Hutchinson-Gilford progeria syndrome: effects on keratinocytes, hair and skin

48 citations , April 2008 in “Human Molecular Genetics”

Progerin affects cell shape but not hair or skin in mice.

research How the leopard gets its spots: a transmembrane peptidase specifies feline pigmentation patterns

March 2013 in “Pigment Cell & Melanoma Research”

A gene called Taqpep affects cat coat patterns like stripes and blotches.

research Vaccines, adjuvants and autoimmunity

248 citations , August 2015 in “Pharmacological Research”

Vaccines are generally safe, but rare autoimmune reactions can occur, often influenced by genetics.

research The Tissue-dependent Keratin 19 Gene Transcription Is Regulated by GKLF/KLF4 and Sp1

119 citations , September 2000 in “Journal of Biological Chemistry”

GKLF/KLF4 and Sp1 control Keratin 19 gene activity, influencing cancer-related changes.

research Delineation of Matriptase Protein Expression by Enzymatic Gene Trapping Suggests Diverging Roles in Barrier Function, Hair Formation, and Squamous Cell Carcinogenesis

100 citations , May 2006 in “American Journal Of Pathology”

Matriptase is crucial for skin barrier, hair growth, and may contribute to skin cancer.

research Dermal papilla-induced hair differentiation of adult epithelial stem cells from human skin

90 citations , August 2004 in “Physiological Genomics”

Dermal papilla cells help skin stem cells grow into hair.

research Constitutive Internalization of the Leucine-rich G Protein-coupled Receptor-5 (LGR5) to the Trans-Golgi Network

58 citations , February 2013 in “Journal of Biological Chemistry”

LGR5 mainly stays inside cells, moving to the trans-Golgi network, and this process is important for its role in cell signaling.

research SARS-CoV-2 Spike Protein S1-Mediated Endothelial Injury and Pro-Inflammatory State Is Amplified by Dihydrotestosterone and Prevented by Mineralocorticoid Antagonism

50 citations , November 2021 in “Viruses”

Spironolactone may help reduce COVID-19 severity in men by blocking harmful effects of certain hormones.

research Premature Graying as a Consequence of Compromised Antioxidant Activity in Hair Bulb Melanocytes and Their Precursors

46 citations , April 2014 in “PLOS ONE”

Gray hair may be caused by lower antioxidant activity in hair cells.

research Cellular plasticity in reprogramming, rejuvenation and tumorigenesis: a pioneer TF perspective

45 citations , August 2023 in “Trends in Cell Biology”

Controlling cellular changes can enable safe rejuvenation without cancer risk.

research Human epidermal neural crest stem cells as a source of Schwann cells

44 citations , January 2015 in “Development”

Human Schwann cells can be quickly made from hair follicle stem cells for nerve repair.

research Apoptosis resistance in peripheral blood lymphocytes of alopecia areata patients

38 citations , September 2004 in “Journal of Autoimmunity”

Alopecia areata patients have more activated T cells in their blood, which may help in developing treatments.

research Hair Follicular Expression and Function of Group X Secreted Phospholipase A2 in Mouse Skin

35 citations , January 2011 in “Journal of Biological Chemistry”

sPLA2-X is crucial for normal hair growth and follicle health.

research Prostaglandin E ₂ Receptor 2 Modulates Macrophage Activity for Cardiac Repair

29 citations , September 2018 in “Journal of the American Heart Association”

EP 2 receptor is essential for heart repair by helping macrophages work properly.

research The circular RNA circNlgnmediates doxorubicin-inducedcardiac remodeling and fibrosis

19 citations , March 2022 in “Molecular therapy. Nucleic acids”

A specific RNA, circNlgn, contributes to heart damage and scarring caused by the cancer drug doxorubicin.

research Ovine Hair Follicle Stem Cells Derived from Single Vibrissae Reconstitute Haired Skin

18 citations , August 2015 in “International Journal of Molecular Sciences”

Ovine hair follicle stem cells can regenerate haired skin and may improve wool production.

research Msx2 Prevents Stratified Squamous Epithelium Formation in the Enamel Organ

18 citations , June 2018 in “Journal of Dental Research”

Msx2 is essential for proper enamel formation by preventing abnormal cell transformation.

research Horse hair follicles: A novel dermal stem cell source for equine regenerative medicine

13 citations , September 2017 in “Cytometry Part A”

Horse hair follicles could be a new source of stem cells for healing horses.

research Small Molecule Treatments Improve Differentiation Potential of Human Amniotic Fluid Stem Cells

11 citations , February 2021 in “Frontiers in Bioengineering and Biotechnology”

Small molecule treatments improve the ability of human amniotic fluid stem cells to become different cell types.

research Expansion of Hair Follicle Stem Cells Sticking to Isolated Sebaceous Glands to Generate in Vivo Epidermal Structures

10 citations , June 2016 in “Cell Transplantation”

Sebaceous glands can help harvest hair follicle stem cells to regenerate skin and hair.

research Epigenetic Effects of Gender-Affirming Hormone Treatment: A Pilot Study of the ESR2 Promoter’s Methylation in AFAB People

9 citations , February 2022 in “Biomedicines”

Testosterone treatment may change estrogen receptor methylation in AFAB individuals.

research Skinny Fat Cells Stimulate Wound Healing

9 citations , June 2020 in “Cell stem cell”

Skinny fat cells help wounds heal faster by releasing fatty acids.

research Hair follicle aging is driven by transepidermal elimination of stem cells via COL17A1 proteolysis

8 citations , April 2017 in “Journal of Dermatological Science”

Hair loss is caused by the breakdown of a protein called COL17A1 in hair follicle stem cells.

research Comparative characterization and osteogenic / adipogenic differentiation of mesenchymal stem cells derived from male rat hair follicles and bone marrow

6 citations , August 2020 in “Cell regeneration”

Hair follicle stem cells are similar to bone marrow stem cells but are better for fat cell research.

research Defining the hair follicle stem cell (Part I)

6 citations , July 2009 in “Journal of Cutaneous Pathology”

Hair follicle stem cells are key for hair growth and skin repair.

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