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Acne treatment with isotretinoin increases the presence of p53, a protein, in skin and oil glands, which may help reduce acne severity.

Finasteride may help improve certain brain function issues linked to dopamine.

TRPA1 and TRPV1 channels don't affect mechanotransduction in rat sinus hair follicles.

The vitamin D receptor can work without its usual activating molecule.

Chronic stress can reduce skin pigmentation.

The protein DDX6 helps keep skin cells renewing properly by controlling the production of certain other proteins and breaking down those that cause cells to mature too quickly.

Trienones are more effective at inhibiting the enzyme linked to hair loss than dienones.

Reducing 5α-reductase activity helps endometrial cells differentiate, aiding pregnancy.

Overexpressing SSAT enzyme reduces prostate tumor growth in mice.

RXR and RAR proteins in skin may help with cell growth, hair growth, and gland function.

Blocking CRF-R1 can reduce alcohol intake in stressed mice.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

The study created a new method to test drugs that affect hormone processing in skin.

PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.

Neurosteroids may help metyrapone reduce cocaine addiction.

Testosterone reduces knee flexibility by affecting relaxin receptors.

The research helps understand how finasteride works and aids drug development.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

Hypoxia and epigenetics are crucial for cell growth and tissue regeneration.

CRH can cause hair loss by promoting cell death in hair growth cells.

Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

PPARγ is crucial for skin health but can have both beneficial and harmful effects.

Combining 5α-reductase and aromatase inhibitors may better reduce estrogen levels.

TRM21 helps control flavonoid production and root hair growth in Arabidopsis thaliana.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

DNMT1 helps turn hair follicle stem cells into fat cells by blocking a specific microRNA.

Blocking a specific enzyme in male rat fetuses leads to the development of nipples and feminized genitalia.