research Time and depth resolved visualisation of the diffusion of a lipophilic dye into the hair follicle of fresh unfixed human scalp skin
The dye quickly penetrates hair follicles, mainly through the gap, not the surrounding skin.
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research Follicular Unit Coupling—The Role of Slot Grafting in Hair Transplantation
Slot grafting can improve hair transplantation results.
research Creating slits to the right depth: Innovative use of micropore tape for depth control on an 18-gauge needle in hair restoration surgery
The document concludes that using micropore tape on an 18-gauge needle can control depth in hair restoration surgery, reducing scalp trauma and complications.
research Minoxidil Skin Delivery from Nanoemulsion Formulations Containing Eucalyptol or Oleic Acid: Enhanced Diffusivity and Follicular Targeting
Eucalyptol and oleic acid in nanoemulsions improve minoxidil delivery to hair follicles, potentially enhancing hair loss treatment.
research Hair follicle-targeted baicalin nanocrystal delivery using microneedles for long-acting treatment of androgenetic alopecia
research Bioavailability assessment of topical delivery systems: Effect of vehicle evaporation upon in vitro delivery of minoxidil from solution formulations
Minoxidil's effectiveness decreases as vehicle evaporates; concentration and thermodynamic activity matter.
research HIV pre-exposure prophylaxis in transgender women: a subgroup analysis of the iPrEx trial
PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.
research Follicular delivery of spironolactone via nanostructured lipid carriers for management of alopecia
Using nanostructured lipid carriers to deliver spironolactone could improve treatment for hair loss.
research Dissolving Microneedle Patch Integrated with Microspheres for Long-Acting Hair Regrowth Therapy
A new microneedle patch can help regrow hair over a long time.
research Postmenopausal virilization after spousal use of topical androgens
A woman developed male traits from accidental contact with her husband's testosterone gel.
research Poly (lactic-co-glycolic acid)-based microneedles for drug delivery across different biological barriers
PLGA-based microneedles show promise for painless, long-term drug delivery but need design and safety improvements.
research Dual drug co-encapsulation into liposomes and liposome-derived nanosystems for improved synergistic treatment of skin diseases
research Do nanoparticles have a future in dermal drug delivery?
Nanoparticles can improve drug delivery to hair follicles but struggle to penetrate deeper skin layers.
research Tratamento de alopecia androgenética masculina com drug delivery por microagulhamento
Microneedling can effectively improve hair growth and thickness in men with hair loss.
research How I Do It: Untouched strip: FUE combined with strip surgery to improve the FU number harvested in one session, preserving an untouched area for a possible future transplant
Combining FUE and strip surgery increases hair harvested in one session and keeps options open for future transplants.
research Recent Advances in the Structural Design of Photosensitive Agent Formulations Using “Soft” Colloidal Nanocarriers
New nanocarriers improve drug delivery for disease treatment.
research Long Hair FUE and the Donor Area Preview
The "open punch" technique for hair transplantation can help reduce damage to hair grafts and may be especially useful for beginners and in cases with curly hair.
research Follicular Unit Plain Speak
The conclusion is that hair transplant surgery should use microscopically dissected natural hair groupings and some new terms were suggested for clarity.
research Spanlastic Nano-Vesicles: A Novel Approach to Improve the Dissolution, Bioavailability, and Pharmacokinetic Behavior of Famotidine
Spanlastic nano-vesicles improve famotidine's effectiveness and absorption.
research Self-Emulsifying Drug Delivery Systems (SEDDS): Measuring Energy Dynamics to Determine Thermodynamic and Kinetic Stability
Solidified SEDDS improve drug stability and bioavailability better than liquid SEDDS.
research Influence of Application Time and Formulation Reapplication on the Delivery of Minoxidil through Hairless Mouse Skin as Measured in Franz Diffusion Cells
Minoxidil absorption in skin is slowed by cleansing, depends on how long it stays on the skin, and is not much affected by reapplication.
research Nanostructured Lipid Carriers Loaded with an Association of Minoxidil and Latanoprost for Targeted Topical Therapy of Alopecia
The new treatment using tiny lipid carriers to deliver minoxidil and latanoprost directly to hair follicles shows promise for alopecia.
research Related Topic: Drug Permeation Through Hair Follicles
Hair follicles are important for drug delivery through the skin, but better methods are needed to understand and improve this process.
research Thiolated and PEGylated silica nanoparticle delivery to hair follicles
Using longer PEG chains helps nanoparticles penetrate hair follicles better, improving drug delivery for conditions like alopecia.
research Quantification of nanoparticle uptake into hair follicles in pig ear and human forearm
Phospholipid-coated nanoparticles penetrate hair follicles better than others, especially in pig ears.
research Penetration and Distribution in Human Skin Focusing on the Hair Follicle
Targeting drugs to hair follicles can treat skin conditions, but reaching deep follicle areas is hard and needs more research.
research Cardamonin-loaded liposomal formulation for improving percutaneous penetration and follicular delivery for androgenetic alopecia
A new liposomal formulation improves drug delivery and hair growth for treating hair loss without causing skin irritation.
research Solid effervescent formulations as new approach for topical minoxidil delivery
Effervescent formulations may improve minoxidil delivery, increasing effectiveness and reducing applications needed.
research Human hair follicle: reservoir function and selective targeting
The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.
research Altered Skin Permeation of Finasteride Using Clove Oil, Urea, and Lyophilized Powder of Grape Seed Extract
Clove oil and grape seed extract increase finasteride skin absorption, while urea decreases it.