research Photo-downregulation of SIRT4 mitigates aging in mice by enhancing H3K9ac via fatty acid metabolism
Red light exposure can slow aging in mice by improving fat metabolism.
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research Comparative Study of Myocardial Biomarkers Among Women with and Without Polycystic Ovarian Syndrome (Pcos) in Nigeria
Women with PCOS in Nigeria have higher heart risk markers, needing early heart health checks.
research Transcriptome and proteome combined analysis of wool fiber diameter regulation mechanism
Key genes and pathways affect wool fiber thickness, improving wool quality.
research Activity of isoflavone in managing polycystic ovary syndrome symptoms (Review)
Isoflavone may help manage PCOS symptoms, but its effectiveness is uncertain.
research Advances in mitochondria-centered mechanism behind the roles of androgens and androgen receptor in the regulation of glucose and lipid metabolism
Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.
research Contribution of lipid Peroxidation to Social Behaviors in individuals with autism spectrum disorders
Lipid peroxidation may worsen social behavior issues in autism.
research Effect of high-fructose diet on the renal cortex of adult male albino rats
High-fructose diets can cause irreversible kidney damage.
research Diagnosis and Treatment of the Cushing Syndrome in Dogs
Daily treatment eventually improved the dog's symptoms.
research Novel Systematics of Nomenclature and Classification of Female Functional Androgenization (Including Polycystic Ovary Syndrome and Non-Classic Congenital Adrenal Hyperplasia)
A new system helps better diagnose and treat female androgenization conditions like PCOS.
research Prevalence and Predictors of Impaired Glucose Tolerance and Diabetes Mellitus Type 2 in Patients with Polycystic Ovary Syndrome
Many women with polycystic ovary syndrome have normal blood sugar, but some may have higher blood sugar levels or diabetes, especially if they are older, overweight, and have certain hormone levels.
research Androgen Therapy in Women: An Endocrine Society Clinical Practice Guideline
The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.
research Side effects of androgen deprivation therapy: monitoring and minimizing toxicity
Androgen deprivation therapy for prostate cancer can cause sexual, physical, and psychological side effects, and doctors should manage these carefully.
research The clinical development of a 5α-reductase inhibitor, finasteride
Finasteride effectively treats BPH, but needs more trials to understand potential.
research Specific dermatologic features of the polycystic ovary syndrome and its association with biochemical markers of the metabolic syndrome and hyperandrogenism
Hirsutism is a strong sign of high male hormones and metabolic problems in women with PCOS, but acne and hair loss are not.
research Transient mitochondrial DNA double strand breaks in mice cause accelerated aging phenotypes in a ROS-dependent but p53/p21-independent manner
Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.
research Ameliorative effects of rutin against metabolic, biochemical and hormonal disturbances in polycystic ovary syndrome in rats
Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.
research A Clinical Approach to Severe Insulin Resistance
Severe insulin resistance can be managed with medication, lifestyle changes, and treatment for related conditions.
research C‐reactive protein promotes adhesion of monocytes to endothelial cells via NADPH oxidase‐mediated oxidative stress
C-reactive protein helps monocytes stick to blood vessel cells by causing oxidative stress.
research Clinical Case Seminar: Postmenopausal androgen excess-challenges in diagnostic work-up and management of ovarian thecosis
The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.
research Selenium and Polycystic Ovary Syndrome; Current Knowledge and Future Directions: A Systematic Review
Selenium might help with insulin resistance and cholesterol in PCOS, but more research is needed to confirm its benefits.
research Gynecologic and andrologic dermatology and the metabolic syndrome
Skin diseases linked to insulin resistance should be managed to prevent diabetes and reduce heart disease risk.
research Hyperandrogénie féminine
The document concludes that managing female hyperandrogenism requires a combination of identifying the cause, lifestyle changes, medication, and cosmetic treatments.
research The Impact of Shampoo Wash Frequency on Scalp and Hair Conditions
Washing hair daily is better and preferred, with no negative effects.
research Does insulin resistance increase thyroid volume in patients with polycystic ovary syndrome?
Insulin resistance is linked to larger thyroid volume in patients with polycystic ovary syndrome.
research Clinical use of 5α-reductase inhibitors
Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.
research An adolescent girl with coexisting ovarian mature cystic teratoma and HAIR-AN syndrome, an extreme subtype of polycystic ovarian syndrome
A teenage girl had both a rare ovarian tumor and a severe form of polycystic ovarian syndrome.
research Sequential estrogen-progestin addition to gonadotropin-releasing hormone agonist suppression for the chronic treatment of ovarian hyperandrogenism: a pilot study.
The treatment effectively reduced hair growth and was safe for patients with PCOS, but it needs better bleeding control.
research Evaluation of androgen-dependent skin findings of polycystic ovary syndrome (PCOS)
The most common skin issues in females with Polycystic Ovary Syndrome (PCOS) are excessive hair growth, hair loss, oily skin, acne, dark skin patches, and skin tags, which may be linked to hormone and insulin levels.
research Proceedings of the XVII International Scientific and Practical Conference
Technology expands design thinking possibilities, requiring a hybrid, reflective approach.
research Clinical analysis of 78 patients with non-classical 21-hydroxylase deficiency
Low-dose glucocorticoid treatment improves pregnancy and birth rates in women with nonclassical 21-hydroxylase deficiency.