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research Protein Kinase C δ Overexpressing Transgenic Mice Are Resistant to Chemically but not to UV Radiation–Induced Development of Squamous Cell Carcinomas: A Possible Link to Specific Cytokines and Cyclooxygenase-2

35 citations , January 2006 in “Cancer Research”

Mice with extra PKCδ resist chemical-induced skin cancer but not UV-induced.

research Whiskers amiss, a new vibrissae and hair mutation near the Krt1 cluster on mouse Chromosome 11

7 citations , April 2000 in “Mammalian Genome”

A new mutation in mice causes crooked whiskers and messy hair.

research Disruption of tubular Flcn expression as a mouse model for renal tumor induction

29 citations , June 2015 in “Kidney International”

Disrupting the Flcn gene in mice causes early kidney cysts and tumors, which can be treated with rapamycin.

research Downregulation of mRNAs Encoding Keratin-Associated Proteins in the Tongue of Mice Fed a High-Fat Diet

January 2024 in “Journal of Hard Tissue Biology”

A high-fat diet may weaken tongue structure by reducing certain protein genes.

research Identification and characterization of the hamster polyomavirus middle T antigen

52 citations , June 1991 in “Journal of Virology”

The hamster polyomavirus middle T antigen is linked to tumors in hamsters and associates with a specific tyrosine kinase.

research TON1 recruiting motif 21 positively regulates the flavonoid metabolic pathway at the translational level in Arabidopsis thaliana

February 2024 in “Planta”

TRM21 helps control flavonoid production and root hair growth in Arabidopsis thaliana.

research 575 Senescent atrophic epidermis retains Lrig1+ stem cells and loses Wnt signaling, a phenotype shared with CD44KO mice

2 citations , August 2016 in “Journal of Investigative Dermatology”

research In vivo Assessment of the Antinociceptive Activity of Ethanol Bark Extract of Thevetia peruviana (Family: Apocynaceae) in Swiss Albino Mice

2 citations , July 2019 in “International Journal of Neuroscience and Behavioral Science”

Thevetia peruviana bark extract reduces pain in mice and may help create new painkillers.

P63 Targeted Deletion Under the FOXN1 Promoter Disrupts Pre- and Post-Natal Thymus Development, Function, and Maintenance, and Induces Severe Hair Loss

research P63 targeted deletion under the FOXN1 promoter disrupts pre-and post-natal thymus development, function and maintenance as well as induces severe hair loss

5 citations , January 2022 in “PloS one”

Deleting the p63 gene in certain cells causes problems in thymus development and severe hair loss in mice.

research [Neurosteroidogenesis and exploratory responses in rodents].

1 citations , January 2014 in “PubMed”

Certain substances can decrease or increase exploratory behavior in rodents.

research The Naked (N) Mutation, Chromosome 15

August 2020

The naked mutation in mice causes hair loss and helps identify keratin genes.

research Comparison of the acute ultraviolet photoresponse in congenic albino hairless C57BL/6J mice relative to outbred SKH1 hairless mice

8 citations , April 2016 in “Experimental dermatology”

B6.Cg-Tyr c−2J Hr hr /J mice have a stronger delayed sunburn reaction and are good for UV research.

research KRASG12D mutant cells are outcompeted by wild type neighbours in adult pancreas in an EPHA2-dependent manner

August 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”

Normal cells outcompete and remove mutant cells in the pancreas with the help of the EphA2 receptor.

research Epidermal PPARγ Is a Key Homeostatic Regulator of Cutaneous Inflammation and Barrier Function in Mouse Skin

9 citations , August 2021 in “International journal of molecular sciences”

PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.

research A SUBPOPULATION OF ITCH RECEPTORS MARKED BY RET EXPRESSION

October 2014 in “Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano)”

A new type of nerve cell involved in itch perception was discovered.

research “Structural imprinting” of the cutaneous immune effector function

4 citations , December 2020 in “Tissue Barriers”

The study explored the role of loricrin, an epidermal protein, in maintaining skin homeostasis and its impact on the immune system. Despite the unexpected discovery of the asymptomatic loricrin knockout (LKO) phenotype, LKO mice revealed altered homeostasis due to redox-driven backup responses. The research aimed to understand how changes in epidermal differentiation affect immune signaling within the skin. By reviewing existing evidence, the study proposed an integrated view of how the peripheral immune system is regulated in squamous epithelial tissue with truncated differentiation, potentially identifying epidermal factors that influence immune effector functions.

research Characterization of hair follicles in Hirosaki hairless rats with deletion of basic hair keratin genes : enlarged medulla, loss of cuticle and long catagen

January 2008 in “Medical Entomology and Zoology”

research 976 Knockout of mTOR/Akt inhibitor REDD1 results in hair cycle-independent dermal adipose expansion by promoting adipocyte differentiation

April 2019 in “Journal of Investigative Dermatology”

Removing REDD1 in mice increases skin fat by making fat cells larger and more numerous.

research The Hairless Phenotype of the Hirosaki Hairless Rat Is Due to the Deletion of an 80-kb Genomic DNA Containing Five Basic Keratin Genes

35 citations , April 2008 in “Journal of Biological Chemistry”

Hirosaki hairless rats lack hair due to missing DNA with key keratin genes.

research Growth retardation and hair loss in transgenic mice overexpressing human H-ferritin gene

8 citations , October 2012 in “Transgenic Research”

Overexpressing the human H-ferritin gene in mice causes mild growth delay and temporary hair loss.

A Population of Radio-Resistant Macrophages in the Deep Myenteric Plexus Contributes to Postoperative Ileus Via Toll-Like Receptor 3 Signaling

research A Population of Radio-Resistant Macrophages in the Deep Myenteric Plexus Contributes to Postoperative Ileus Via Toll-Like Receptor 3 Signaling

6 citations , January 2021 in “Frontiers in Immunology”

Certain immune cells worsen post-surgery gut paralysis by activating a specific immune response.

research Epidermis-specific ablation of claudin-1 in adult mice demonstrates the essential role of a tight junction barrier in skin homeostasis

1 citations , September 2016 in “Journal of Dermatological Science”

Claudin-1 is crucial for maintaining skin barrier and preventing inflammation.

research Alopecia in a Viable Phospholipase C Delta 1 and Phospholipase C Delta 3 Double Mutant

8 citations , June 2012 in “PloS one”

Mutations in Plcd1 and Plcd3 together cause severe hair loss in mice.

research Topical Application of the Synthetic Triterpenoid RTA 408 Protects Mice from Radiation-Induced Dermatitis

61 citations , April 2014 in “Radiation Research”

RTA 408 cream protects mice from radiation skin damage.

research Reviewer #2 (Public Review): CaBP1 and 2 enable sustained CaV1.3 calcium currents and synaptic transmission in inner hair cells

January 2024

CaBP1 and 2 are necessary for maintaining calcium currents and hearing in inner ear cells.

research Introduction: splintering urbanism

January 2007 in “Edward Elgar eBooks”

TSPO might help treat anxiety and depression.

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