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Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.

Disrupting the Flcn gene in mice causes early kidney cysts and tumors, which can be treated with rapamycin.

Researchers found genes and microRNAs that control curly fleece in Chinese Tan sheep.

Organoids help study and treat genetic diseases, offering personalized medicine and therapy testing.

Topical melatonin may reduce skin aging by inhibiting certain cellular pathways.

Disrupting the Tsc2 gene in certain cells leads to thicker skin, larger hair, and changes in hair growth signaling, which can be partly reversed with specific treatment.

TSC2 is crucial for proper hair follicle development and patterning.

High mTORC1 activity slows hair growth and causes it to lose color.

mTORC1 activity is important for hair growth and color, and targeting it could help treat hair loss and greying.

Early diagnosis, genetic testing, and personalized care are essential for managing tuberous sclerosis.

Diet changes can improve skin health by altering the immune response and skin microbiome.

Blocking mTORC1 activity could increase hair pigmentation and potentially reverse greying.

Mouse skin fibroblasts vary in function and adaptability based on their environment.

Tgm2 helps stabilize dying cells and aids fibroblast attachment to the extracellular matrix.

Fibroblast spheres can form stem cells, but marker distribution needs more study.

A specific group of skin stem cells was found to help maintain hair follicle cells.

Researchers converted human embryonic stem cells into trophoblast stem cells using specific transcription factors.

Skin heals with scars because only one type of fibroblast is used, not a mix.

Fibroblast and immune cell interactions affect tissue repair and fibrosis.

TNC+ fibroblasts play a key role in skin inflammation by interacting with T cells.

Fibroblasts can be mistaken for neural cells, so functional validation is needed.

Scientists found a new type of skin cell that could help with skin repair and these cells work better with a certain protein.

Human hair follicle stem cells can become smooth muscle cells using specific growth factors.

The treatment combining laser and fetal fibroblasts effectively reduces scarring.

Telocytes in the scalp may help with skin regeneration and maintenance.

HPV16-transformed cells can change human skin cell properties, aiding tumor growth.

Different types of fibroblasts play specific roles in wound healing and cancer, which could help improve treatments.

3D cell spheroids can help reduce scars by delivering therapeutic vesicles.

Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.

Senescent fibroblasts can help start tumors in normal skin cells.