research Targeting of Smoothened for therapeutic gain
Targeting the Smoothened receptor shows promise for treating certain cancers.
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930-960 / 1000+ resultsresearch Immunological challenges associated with artificial skin grafts: available solutions and stem cells in future design of synthetic skin
Artificial skin grafts face immune rejection, but stem cells may improve future designs.
research Advances in Chitosan-Based Nanoparticles for Drug Delivery
Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.
research Indian Medicinal Herbs and Formulations for Alzheimer’s Disease, from Traditional Knowledge to Scientific Assessment
Indian herbs like Bacopa monnieri and Centella asiatica may help memory, but more research is needed.
research The Proteins of Hair and Other Hard α-Keratins
research Pharmacologic interventions in aging hair
Minoxidil and Finasteride are effective for male baldness; more research is needed for hair aging treatments.
research Directed Expression of Keratin 16 to the Progenitor Basal Cells of Transgenic Mouse Skin Delays Skin Maturation
Keratin 16 delays skin maturation and affects skin and hair development in mice.
research Scarless wound healing: Transitioning from fetal research to regenerative healing
Understanding how baby skin heals without scars could help develop treatments for adults to heal wounds without leaving scars.
research A Missense Mutation within the Helix Initiation Motif of the Keratin K71 Gene Underlies Autosomal Dominant Woolly Hair/Hypotrichosis
A specific gene mutation causes woolly hair and hair loss.
research Four Independent Mutations in the Feline Fibroblast Growth Factor 5 Gene Determine the Long-Haired Phenotype in Domestic Cats
FGF5 gene mutations cause long hair in domestic cats.
research Multifunctional Self-Assembled Peptide Hydrogels for Biomedical Applications
Peptide hydrogels are promising for drug delivery and tissue repair in medicine.
research An overview of chemical straightening of human hair: technical aspects, potential risks to hair fibre and health and legal issues
Chemical hair straightening can damage hair and health, needing safer alternatives and stricter regulations.
research Amino acid–derived defense metabolites from plants: A potential source to facilitate novel antimicrobial development
Plant-derived amino acids can help develop new antimicrobial drugs.
research Polycystic Ovary Syndrome: A Comprehensive Review of Pathogenesis, Management, and Drug Repurposing
PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.
research Fucoidan-derived carbon dots against Enterococcus faecalis biofilm and infected dentinal tubules for the treatment of persistent endodontic infections
Fucoidan-derived carbon dots can effectively treat root canal infections by killing bacteria and are safer than traditional disinfectants.
research The Skin and Inflamm-Aging
Aging skin causes inflammation that affects the whole body.
research FLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylation
The protein FLCN is involved in cellular cleanup and is regulated by ULK1.
research Deimination and Peptidylarginine Deiminases in Skin Physiology and Diseases
PADs are crucial for healthy skin and hair, and their imbalance can cause skin and hair disorders.
research Medicinal Chemistry of Drugs with N-Oxide Functionalities
N-oxides are important in medicine for improving drug properties and targeting.
research Targeting integrin pathways: mechanisms and advances in therapy
New therapies are being developed that target integrin pathways to treat various diseases.
research Myricetin: A Significant Emphasis on Its Anticancer Potential via the Modulation of Inflammation and Signal Transduction Pathways
Myricetin shows promise as an anticancer agent by reducing inflammation and enhancing drug effectiveness.
research LC-ESI-QTOF-MS/MS Analysis, Cytotoxic, Antiviral, Antioxidant, and Enzyme Inhibitory Properties of Four Extracts of Geranium pyrenaicum Burm. f.: A Good Gift from the Natural Treasure
Geranium pyrenaicum extracts show potential for cancer, antiviral, and enzyme inhibition treatments.
research Human Hair and the Impact of Cosmetic Procedures: A Review on Cleansing and Shape-Modulating Cosmetics
Future hair cosmetics will be safer and more effective.
research SARS-CoV-2 Non-Structural Proteins and Their Roles in Host Immune Evasion
SARS-CoV-2 proteins help the virus avoid the immune system, delaying response and increasing inflammation.
research Characterization of the Human Hair Keratin–Associated Protein 2 (KRTAP2) Gene Family
KRTAP2 genes are crucial for hair structure and may impact hair disorders and treatments.
research Multifaceted role of keratins in epithelial cell differentiation and transformation
research Newly Developed Targeted Therapies Against the Androgen Receptor in Triple-Negative Breast Cancer: A Review
Targeting androgen receptors shows promise for treating triple-negative breast cancer, but more research is needed.
research Overexpression of the calcium sensing receptor accelerates epidermal differentiation and permeability barrier formation in vivo
Increasing calcium sensing receptor speeds up skin and hair development in mice.
research Functional Food Nutrients, Redox Resilience Signaling and Neurosteroids for Brain Health
Functional foods and nutrients like flavonoids, vitamin D, omega-3s, and probiotics can boost brain health and reduce stress.
research Follicular Fluid: A Powerful Tool for the Understanding and Diagnosis of Polycystic Ovary Syndrome
Analyzing follicular fluid can help predict and improve outcomes for women with PCOS undergoing fertility treatments.