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Two patients had a unique form of trichothiodystrophy with reduced high-sulfur proteins in their hair.

ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.

Genotyping for NUDT15 p.Arg139Cys can help predict thiopurine side effects in Japanese IBD patients.

Bendamustine combined with tucidinostat may effectively treat adult T-cell leukemia.

Daily subcutaneous testosterone effectively restores testosterone levels in men.

Trastuzumab deruxtecan is effective for HER2-positive breast cancer but requires careful management of side effects.

Adding dutasteride to therapy may improve treatment for advanced salivary duct cancer.

TTD hair is brittle due to fewer sulfur amino acids and unstable disulfide bonds.

UV-enhanced trichoscopy helps diagnose hair shaft disorders like pili annulati.

Two sisters had a rare hair condition without other usual symptoms.

Trichothiodystrophy causes abnormal protein deposits and distortion in hair follicles.

Thyroid ultrasounds are essential but need skill and experience for accurate results.

Disitamab vedotin and gemcitabine effectively treated bladder cancer without major side effects.

Electron Beam Tomography (EBT) is a useful additional test to stress testing for detecting heart disease.

A woman with inflammatory bowel disease improved after treatment with ustekinumab for a rare skin condition associated with her disease.

UVFD helps quickly diagnose hair loss conditions in children.

Researchers found four natural compounds that can change DHT levels in prostate cancer cells.

Androgen-deprivation therapies increase the risk of certain heart conditions, but testosterone treatment may help.

CTP-543 significantly improved eyebrow and eyelash regrowth and patient satisfaction in adults with alopecia areata.

Cutaneous ultrasound is a useful tool for diagnosing and assessing inflammation in tinea capitis.

Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.

CTP-543 effectively promotes hair regrowth in adults with moderate to severe alopecia areata.

A child with trichothiodystrophy also had autoimmune thyroiditis and anemia, which is a new finding.

Prenatal diagnosis of trichothiodystrophy is possible in the second trimester using fetal eyebrow biopsy, with sulfur content analysis being more reliable.

Combining ultrasound and microneedles improves drug delivery through the skin.

GC10/DOX hydrogel shows promise as an effective thyroid cancer treatment.

Deep phenotyping helps distinguish between xeroderma pigmentosum and trichothiodystrophy, aiding in diagnosis and treatment.