research Current Literature Review
The document suggests that finasteride may cause depression and suicidal thoughts, while prostate surgery does not harm sexual health.
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research Insights into the peripheral nature of persistent sexual dysfunction associated with post-finasteride, post-SSRI and post-accutane syndromes: lessons learned from a case study
Peripheral treatments showed some improvement in sexual dysfunction, but central symptoms remain challenging.
research Beeinflussen Medikamente gegen das benigne Prostatasyndrom Stimmung oder Kognition?
Medications for benign prostatic syndrome can cause cognitive issues and depression.
research Inappropriate Sexual Behaviors in Patients with Vascular Dementia: Possible Response to Finasteride
Finasteride may help reduce inappropriate sexual behaviors in dementia patients with prostate issues.
research Low-sulfur hair syndrome associated with UVB photosensitivity and testicular failure
Low-sulfur hair syndrome can cause UVB sensitivity and testicular failure.
research Why Odds Ratios Can Be Tricky Statistics
Odds Ratios can be misleading; it's better to also present risk and Relative Risks for clarity.
research Efficacy and Safety of a Proprietary Free Fatty Acid Rich Saw Palmetto Extract (USPlus<sup>®</sup> PRO) for Lower Urinary Tract Symptoms in Males: A Randomized, Double-Blind, Placebo-Controlled Trial
USPlus PRO saw palmetto extract improves urinary symptoms and is safe for men.
research Uterine transplantation in transgender women
Uterine transplants for transgender women are feasible but need more research.
research Dutasteride, a novel dual 5-A reductase inhibitor, reduces serum DHT to a greater extent versus finasteride and achieves finasteride maximal reduction in a larger proportion of patients
Dutasteride reduces DHT more effectively than finasteride.
research Persistent Sexual Side Effects of Finasteride: Could They Be Permanent?
Finasteride may cause long-lasting sexual side effects.
research Finasteride as a therapy for hidradenitis suppurativa
Finasteride improves hidradenitis suppurativa but not for child-bearing women.
research Lipid Profile and 5α-Reductase Inhibition Activity of Proprietary Ultrahigh-Pressure Supercritical Carbon Dioxide and Hexane Saw Palmetto Extracts
UHP-sCESr is as effective as HESr for treating BPH symptoms.
research Sub-acute cutaneous lupus erythematosus following nitrofurantoin: causative or coincidental?
Nitrofurantoin may cause sub-acute cutaneous lupus erythematosus.
research Should Finasteride Be Routinely Given Preoperatively for TURP?
Finasteride may reduce bleeding after TURP, but more research needed.
research COMPARISON OF FINASTERIDE AND ALPHA‐BLOCKERS AS INDEPENDENT RISK FACTORS FOR ERECTILE DYSFUNCTION
Age and other health issues affect erectile dysfunction more than finasteride or alpha-blockers.
research Management of neonates and children with male pseudohermaphroditism
Individuals with male pseudohermaphroditism often do better raised as females with early surgery.
research BPH Medications May Increase Risk of Self-Harm, Depression
BPH medications may increase the risk of self-harm and depression, especially in the first 18 months.
research Comparison of clinical trials with finasteride and dutasteride.
Dutasteride reduces DHT more than finasteride, but both drugs improve BPH symptoms similarly.
research Prevention and treatment of experimental prostate cancer in lobund-wistar rats. I. Effects of estradiol, dihydrotestosterone, and castration
Estradiol and castration reduced prostate cancer development in rats when applied at early stages, but were ineffective after cancer was established.
research Dual deficiency of melatonin and dihydrotestosterone promotes stromal cell damage and mediates prostatitis via the cGAS-STING pathway in sleep-deprived mice
Lack of sleep in mice leads to prostatitis by reducing certain hormones and activating an inflammatory pathway, which can be temporarily fixed with normal sleep.
research Correlations between hormonal intrauterine devices and androgenic skin conditions: A retrospective cohort study
Hormonal intrauterine devices (IUDs) may cause or worsen skin conditions influenced by androgens.
research Editorial Comment
Dutasteride reduces prostate cancer risk by 23% in high-risk men.
research Finasteride-Associated Central Serious Chorioretinopathy
research MP-03.07: Does finasteride have a preventive effect on a chronic bacterial prostatitis? Pilot study using an animal model
The effectiveness of finasteride for preventing chronic bacterial prostatitis is unclear.
research Finasteride in the treatment of patients with benign prostatic hyperplasia: a review
Finasteride effectively reduces prostate size and lowers surgery risk in men with benign prostatic hyperplasia.
research Effect of androgen on nitric oxide synthase positive neurons in the medial preoptic area
Androgen, especially DHT, is crucial for erectile function in rats by affecting specific brain neurons.
research Esrp1-Regulated Splicing of Arhgef11 Isoforms Is Required for Epithelial Tight Junction Integrity
The study concluded that specific proteins are necessary to maintain the structure that holds epithelial cells tightly together.
research 474 Stabilizing mutations of KLHL24 ubiquitin ligase cause loss of keratin 14 and human skin fragility
Certain mutations in the KLHL24 gene cause a skin disorder by breaking down an important skin protein.
research Protective effects of finasteride against testosterone-induced calcium oxalate crystallization and crystal-cell adhesion
Finasteride helps prevent kidney stones, but side effects need more research.
