research Non-competitive androgen receptor inhibition in vitro and in vivo
Two new compounds can block androgen receptor activity in different ways and may lead to new treatments for androgen-related diseases.
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research MP89-08 POST-FINASTERIDE SYNDROME: REAL OR IMAGINED?
Finasteride 1mg linked to diverse symptoms; other treatments improve erectile function in rats.
research In Silico Screening of DrugBank Compounds as Potential Inhibitors for Human Steroid 5α-Reductase 2 for Androgen-Related Diseases
Stiripentol shows promise as a potential treatment for androgen-related diseases but needs more testing.
research Review: Adding α1-blockers to 5α-reductase inhibitors improves lower urinary tract symptoms in men
Combining α1-blockers with 5α-reductase inhibitors improves urinary symptoms in men.
research The 5α-Recluctase System and Its Inhibitors
5 alpha-reductase inhibitors, like finasteride, are used to treat conditions like prostate issues and skin disorders.
research Synthesis, antiproliferative activity, acute toxicity and assessment of the antiandrogenic activities of new androstane derivatives
research Treatment of female pattern hair loss with oral antiandrogens
Oral antiandrogens effectively treat female hair loss, with better results in higher hair loss grades.
research Which chemicals should be grouped together for mixture risk assessments of male reproductive disorders?
Group a wide range of chemicals, not just phthalates, for assessing risks to male reproductive health.
research Electrochemical studies on minoxidil and its determination in tablets by differential-pulse polarography
Method measures minoxidil in tablets accurately and easily.
research Three isostructural solvates of finasteride and their solid-state characterization
Three new finasteride solvates found, change forms under different drying conditions.
research Voltammetric reduction of finasteride at mercury electrode and its determination in tablets
New, cheaper method measures finasteride in tablets accurately and quickly.
research Liposomes in cancer therapy
Liposomes show promise in cancer treatment by delivering drugs with less toxicity and improved effectiveness.
research Effects of dihydrotestosterone on rat dermal papilla cells in vitro
Dihydrotestosterone (DHT) doesn't affect rat skin cell growth, but it does change cell cycle, protein levels, and other cell functions, potentially shortening hair growth cycle.
research Persistent Erectile Dysfunction after Discontinuation of 5-Alpha Reductase Inhibitor Therapy in Rats Depending on the Duration of Treatment
Long-term use of dutasteride can cause permanent erectile dysfunction in rats.
research Inhibition of 5α Reductase Impairs Cognitive Performance, Alters Dendritic Morphology and Increases Tau Phosphorylation in the Hippocampus of Male 3xTg-AD Mice
Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.
research ENRIQUECIMENTO AMBIENTAL ASSOCIADO A PROMOÇÃO DO BEM ESTAR PARA CAMUNDONGOS MANTIDOS EM BIOTÉRIOS
research peri ‐Xanthenoxanthene (PXX): a Versatile Organic Photocatalyst in Organic Synthesis
PXX is an effective and affordable photocatalyst for creating new chemical bonds in organic synthesis.
research The E6/E7 oncogenes of human papilloma virus and estradiol regulate hedgehog signaling activity in a murine model of cervical cancer
HPV genes and estradiol increase a cancer-related signaling pathway, which may be targeted for cervical cancer treatment.
research Adsorptive cathodic stripping determination of minoxidil in pharmaceutical, cream and shampoo products
Researchers developed a sensitive method to measure minoxidil in various products with high accuracy.
research DESENVOLVIMENTO BIOTECNOLÓGICO DE SÉRUM REJUVENESCEDOR ANTIOXIDANTE CONTENDO ATIVO LIPÍDICO ORIUNDO DA RANA CATESBEIANA SHAW
The serum is effective, safe, and stable for skincare.
research The 46th Annual Meeting of the Irish Endocrine Society Meeting Programme and Abstracts 2022
Electrical stimulation with a low-calorie diet reduces appetite, weight, and blood pressure in obese people with sleep apnea.
research Simultaneous Quantification of Dutasteride and Silodosin Using a Stability-Indicating RP-HPLC Approach
The method accurately and quickly measures silodosin and dutasteride in mixtures.
research ASPECTOS DA ESTRONGILOIDÍASE EM CÃES E O SEU IMPACTO NO ÂMBITO DA SAÚDE PÚBLICA
research ABATE CLANDESTINO DE BOVINOS: RISCOS E CONSEQUÊNCIAS
research O VÍRUS DA GRIPE AVIÁRIA (H5N1): UMA REVISÃO DE LITERATURA
research LASERTERAPIA E SUAS APLICAÇÕES NO TRATAMENTO E REABILITAÇÃO DE PEQUENOS ANIMAIS COM OSTEOARTROSE
research AVALIAÇÃO DA CRIPTOSPORIDIOSE EM CÃES E SUAS IMPLICAÇÕES NA SAÚDE ÚNICA
research Study of Digital Video Microscopy in the Diagnosis of Non-Scarring Alopecia
Digital video microscopy is a useful non-invasive tool for diagnosing non-scarring alopecia.
research Patched-assoziierte Tumoren: Modifikatorgene und Pathogenese
The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.
research Association of eNOS and STAT6 Gene Polymorphisms with the Susceptibility of Polycystic Ovary Syndrome in South Indian Women
Certain gene variations may increase the risk of PCOS in South Indian women.