3 citations
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December 2022 in “Nutrients” Limonin from young citrus fruits may help with hair growth by affecting cell growth and hair cycle pathways.
1 citations
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November 2024 in “EMBO Reports” Deleting Gpr54 speeds up hair growth and regeneration.
February 2026 in “Chemical Engineering Journal” PCA hydrogel promotes hair growth by enhancing blood vessel formation and hair follicle stem cell activity.
November 2025 in “Biomolecules” FGF22 helps hair follicle stem cells grow and develop.
May 2025 in “Journal of Nanobiotechnology” The gel improves hair regrowth and reduces irritation in alopecia areata treatment.
April 2025 in “Antioxidants” Rhus semialata gall extract and Penta-O-Galloyl-β-D-Glucose may effectively reduce hair loss.
March 2025 in “Regenerative Therapy” Spirulina maxima extract may help hair growth by boosting cell activity.
January 2025 in “Journal of Ethnopharmacology” Dahuang-Gancao Decoction improves hair growth in androgenetic alopecia.
March 2024 in “Bioactive Materials” New treatment using engineered nanovesicles in hydrogel improves hair growth by repairing hair follicle cells in a mouse model of hair loss.
December 2023 in “European Journal of Pharmacology” C3G and Vitisin A may help prevent hair loss by blocking male hormones and stopping hair cell death.
24 citations
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March 2020 in “Cells” Natural small molecules can help treat diseases by activating or inhibiting the Wnt pathway.
113 citations
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June 2015 in “Stem Cell Research & Therapy” Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.
32 citations
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November 2016 in “Journal of Dental Research” Pannexin 3 is important for bone formation and the development of bone cells.
October 2024 in “Biology” Dermal papilla cells can help regrow hair and are promising for hair loss treatments.
August 2024 in “Receptors” Vitamin D receptor is crucial for skin wound healing.
68 citations
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April 2012 in “Journal of Investigative Dermatology” The conclusion is that Fgf18 and Tgf-ß signaling could be targeted for hair loss treatments.
12 citations
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June 2017 in “Cell Cycle” Minoxidil foam helps hair growth by increasing good proteins and decreasing bad pathways in men with hair loss.
April 2017 in “Journal of Investigative Dermatology” SM04755 may be an effective topical treatment for psoriasis.
Wnt-activating drugs generally do not increase cancer risk.
January 2020 in “Elsevier eBooks” Plant-based chemicals may help hair growth and prevent hair loss but need more research to compete with current treatments.
9 citations
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December 2002 in “Novartis Foundation Symposium” LEF1 is essential for the development of airway glands and is regulated by the Wnt/ß-catenin pathway.
April 2019 in “Journal of Investigative Dermatology” Activating the Sonic hedgehog pathway can help regenerate hair follicles during wound healing in mice, potentially improving regeneration after injury.
29 citations
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July 2014 in “PLoS ONE” Inactivating β-catenin is essential for chick retina regeneration.
13 citations
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January 2021 in “RSC chemical biology” Wnt activation shows promise for regenerative medicine but requires selective targeting to minimize risks like cancer.
4 citations
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January 2019 in “International journal of molecular sciences” Genetically modified sheep with more β-catenin grew more wool without changing the wool's length or thickness.
April 2017 in “Journal of Investigative Dermatology” A virus protein can activate a pathway that may lead to abnormal hair follicle development.
26 citations
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October 2016 in “Biomolecules & Therapeutics” 3-Deoxysappanchalcone helps human hair cells grow and stimulates hair growth in mice by affecting certain cell signaling pathways.
3 citations
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April 2014 in “Journal of Dietary Supplements” CARI ONE helps start hair growth and makes hair follicles bigger and more numerous.
1 citations
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January 2013 in “MedChemComm” PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.
77 citations
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February 2017 in “Stem Cell Reports” SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.