January 2018 in “Figshare” Melatonin helps Cashmere goat hair follicles grow by affecting genes and cell signals important for their development and environment.
January 2025 in “JOURNAL of SIBERIAN MEDICAL SCIENCES” Age-related hair loss is linked to changes in blood vessels, stem cells, and aging cells, and understanding these can help keep hair healthy as we age.
7 citations
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January 2021 in “Biology” Some COVID-19 patients have different skin problems, which might be the only sign of the virus or related to other health issues.
208 citations
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July 2001 in “Journal of The American Academy of Dermatology” Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.
2 citations
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October 2016 Chemotherapy and radiotherapy can cause skin side effects like rashes, hair loss, and nail changes, which are usually managed with conservative treatments.
January 2025 in “Research” A new metformin-based treatment may effectively promote hair growth with fewer side effects.
August 2021 in “Oxford University Press eBooks” The skin is a complex organ that protects the body, regulates temperature, and has roles in immunity, hormone function, and vitamin D metabolism.
July 2020 in “International Journal of Research” High testosterone increases heart disease risk in women with PCOS.
December 2015 in “Vascular Pharmacology” Hair papilla cells are crucial for blood vessel development in hair follicles, affecting hair growth and loss.
August 2009 in “Expert Review of Dermatology” Pregnancy can cause skin changes and conditions that need correct diagnosis and treatment for the health of the mother and baby.
Alopecia involves complex disruptions in immune, oxidative, apoptotic, and regenerative pathways within the hair follicle microenvironment. This review highlights the potential of a biomarker-guided therapeutic map to improve treatment precision by focusing on six key biomarkers: TNF-α, IL-6, MDA, caspase-3, VEGF, and β-catenin. Analysis of 15 animal studies from 2014 to 2024 revealed that TNF-α and IL-6 are linked to inflammation and immune damage, MDA to oxidative stress, and caspase-3 to apoptosis. Conversely, VEGF and β-catenin, which support angiogenesis and regeneration, are suppressed in alopecia but can be restored through effective treatments. Therapeutic strategies such as botanical extracts, bioactive compounds, and advanced delivery systems have shown promise in reducing harmful biomarkers and enhancing regenerative pathways. This biomarker-centered approach offers a promising framework for developing targeted, multitargeted alopecia treatments.
October 2005 in “CRC Press eBooks” Telogen effluvium is a condition where hair falls out due to various factors like illness, stress, or nutrient deficiency.
36 citations
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August 2022 in “Molecular Therapy — Nucleic Acids” Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.
27 citations
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November 2010 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft” New laser therapies are effective for skin damage, hair removal, and fat reduction.
2 citations
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January 2019 The document concludes that autoimmune skin disorders are treated with corticosteroids and immunosuppressive drugs.
Fat stem cell treatment is safe and increases hair density for hair loss, but more research is needed.
32 citations
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September 1989 in “Medical Clinics of North America” Skin problems are common in lupus, important for diagnosis, and can be triggered by sunlight.
5 citations
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January 2023 in “Cell proliferation” Chick embryo extract helps rat hair follicle stem cells potentially turn into Schwann cells, important for the nervous system.
May 2021 in “Bőrgyógyászati és venerológiai szemle” Some skin symptoms, like chilblain-like lesions, can help identify COVID-19 and show how the immune system is responding.
6 citations
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October 1979 in “Chest” Minoxidil lowers blood pressure without worsening lung pressure but can cause increased hair growth.
8 citations
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June 2025 in “Stem Cell Research & Therapy” Exosome therapy may help treat diabetic nerve damage, but more research is needed.
2 citations
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September 2024 in “Lasers in Surgery and Medicine” Noninvasive scalp imaging techniques can improve patient care by reducing the need for biopsies.
December 2025 in “Experimental Dermatology” Improving blood vessel health and controlling uric acid may help manage alopecia areata.
January 2024 in “Toxicologic Pathology” The skin protects the body, helps heal wounds, stores energy, and supports health.
June 2026 in “Frontiers in Bioengineering and Biotechnology” This review discusses the advancement of hair follicle organoids towards immune-competent hair follicle microphysiological systems (HF-MPS), which aim to better replicate the immune, vascular, neural, and dynamic regulatory features of native hair follicles. These systems are particularly important for studying immune-mediated hair disorders like alopecia areata, where immune privilege collapse and inflammatory infiltration are key issues. The review outlines the structural basis of HF engineering and defines immune competence as maintaining immune privilege, regulating hair follicle cycling and regeneration, and managing inflammatory injury. It also explores engineering strategies such as local immune microenvironment control and dynamic perfusion. The applications of HF-MPS in disease modeling, drug evaluation, and regenerative medicine are discussed, emphasizing that these systems are evolving platforms rather than complete replacements for existing models.
April 2026 in “The National Medical Journal of India” Regular eye exams are important for detecting serious complications in lupus patients.
3 citations
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March 2022 in “Medicine” Systemic lupus erythematosus treatment can restore vision in patients with retinal artery occlusion.
February 2025 in “Indian Dermatology Online Journal” Pincer nails are rare in lupus patients and may be managed conservatively.
August 2022 in “F1000Research” Digital gangrene can be a rare first sign of late-onset systemic lupus erythematosus.
6 citations
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February 2021 in “Frontiers in Neurology” Cyclosporine-A can cause serious blood clots in the brain, so patients need careful monitoring.