research Editorial: Synthesis, functionalization, and clinical translation of pharmaceutical biomaterials
New pharmaceutical biomaterials, especially nanomaterials, show promise for improving cancer treatment and disease diagnosis.
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600-630 / 1000+ results research Do Hair Bulb Melanocytes Undergo Apotosis During Hair Follicle Regression (Catagen)?
Hair follicle melanocytes die during hair regression.
research Inhibition of neurosteroid synthesis increases asphyxia-induced brain injury in the late gestation fetal sheep
Reducing neurosteroid levels worsens brain injury in fetal sheep.
research Hippocampal 3α,5α-THP may alter depressive behavior of pregnant and lactating rats
Higher 3α,5α-THP levels in the brain may reduce depression in pregnant rats.
research A subpopulation of itch‐sensing neurons marked by Ret and somatostatin expression
Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.
research JAK Inhibitors for Treatment of Alopecia Areata
JAK inhibitors can effectively reverse hair loss in people with alopecia areata.
research The Vitamin D Receptor as Tumor Suppressor in Skin
Vitamin D and its receptor may help prevent skin cancer.
research Topical drug delivery strategies for enhancing drug effectiveness by skin barriers, drug delivery systems and individualized dosing
Improving topical drug delivery involves overcoming skin barriers and using personalized dosing to enhance effectiveness.
research Treatment of pediatric alopecia areata: A systematic review
Topical corticosteroids are the best initial treatment for children's alopecia areata.
research Vitamin D and skin diseases: A review
Vitamin D is important for skin health and can help treat psoriasis, atopic dermatitis, and vitiligo.
research A Comprehensive Literature Review of JAK Inhibitors in Treatment of Alopecia Areata
JAK inhibitors show promise in effectively treating hair loss from alopecia areata.
research Intelligent nanotherapeutic strategies for the delivery of CRISPR system
Smart delivery methods for CRISPR gene editing are crucial for clinical success.
research CXCL12+ dermal fibroblasts promote neutrophil recruitment and host defense by recognition of IL-17
CXCL12+ fibroblasts help recruit neutrophils to fight skin infections.
research IL-36γ drives skin toxicity induced by EGFR/MEK inhibition and commensal Cutibacterium acnes
A protein called IL-36γ causes skin side effects from certain cancer treatments when combined with a common skin bacteria.
research MicroRNA-Enriched Exosomes from Different Sources of Mesenchymal Stem Cells Can Differentially Modulate Functions of Immune Cells and Neurogenesis
Exosomes from different stem cell sources affect immune cells and brain cell growth differently.
research The impact of VDR expression and regulation in vivo
VDR regulation varies by tissue and is crucial for its biological functions.
research The Vitamin D Receptor Is Required for Mouse Hair Cycle Progression but not for Maintenance of the Epidermal Stem Cell Compartment
Vitamin D Receptor is needed for hair growth in mice but not for skin stem cell maintenance.
research Activation of AR Sensitizes Breast Carcinomas to NVP-BEZ235's Therapeutic Effect Mediated by PTEN and KLLN Upregulation
Breast cancer treatments work better with AR activation, improving results and reducing side effects.
research Chemical Profiling, Pharmacological Insights and In Silico Studies of Methanol Seed Extract of Sterculia foetida
Sterculia foetida seed extract shows promise for therapeutic use due to its anti-inflammatory and pain-relief properties.
research Enhanced Sensitivity to Ethanol-Induced Inhibition of LTP in CA1 Pyramidal Neurons of Socially Isolated C57BL/6J Mice: Role of Neurosteroids
Social isolation makes mice more sensitive to alcohol's effects on brain function.
research Exploring the relationship between anastasis and mitochondrial ROS-mediated ferroptosis in metastatic chemoresistant cancers: a call for investigation
Targeting specific molecular pathways may improve treatments for chemoresistant cancers.
research Silk Fibroin and Its Nanocomposites for Wound Care: A Comprehensive Review
Silk fibroin shows promise for wound care but faces challenges in becoming widely available.
research Opportunities and challenges of bacterial extracellular vesicles in regenerative medicine
Bacterial extracellular vesicles could revolutionize regenerative medicine but need safety improvements.
research The microfollicle: a model of the human hair follicle for in vitro studies
Microfollicles can effectively model human hair follicles for research and testing.
research Suppression of Vitamin D Receptor and Induction of Retinoid X Receptor α Expression During Squamous Differentiation of Cultured Keratinocytes
As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.
research Lack of evidence of a role for the neurosteroid allopregnanolone in ethanol-induced reward and c-fos expression in DBA/2 mice
Allopregnanolone likely doesn't influence ethanol's rewarding effects in these mice.
research Female pattern hair loss—An update
Female pattern hair loss has multiple causes and treatments, with new therapies showing promise.
research Therapy for Alopecia Areata in Mice by Stimulating the Hair Cycle with Parathyroid Hormone Agonists Linked to a Collagen-Binding Domain
PTH-CBD helps reduce hair loss in mice by stimulating hair growth directly.
research Inducible expression of gasdermin A3 in the epidermis causes epidermal hyperplasia and skin inflammation
Gasdermin A3 overexpression in skin causes inflammation and hair loss.
research Beyond the Surface: Understanding Demodex and Its Link to Blepharitis and Facial Dermatoses
High levels of Demodex mites can cause eye and skin problems.