119 citations
,
July 2016 in “Annals of the New York Academy of Sciences” Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.
50 citations
,
October 1986 in “European journal of pediatrics” A boy with severe Vitamin D-resistant rickets did not respond to treatment and lacked a common symptom, suggesting a need for alternative treatments.
31 citations
,
January 2007 in “Journal of biological chemistry/The Journal of biological chemistry” Stress activates a special function of the Vitamin D receptor with the help of c-Jun, which can also prevent cell death.
10 citations
,
September 2015 in “PLoS ONE” New mutations in the VDR gene cause vitamin D-resistant rickets without hair loss.
4 citations
,
January 2017 in “Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism” Two different mutations in the vitamin D receptor gene cause different symptoms and responses to treatment in Lebanese patients with hereditary rickets.
2 citations
,
September 2022 in “Bioscientia medicina” Topical vitamin D is effective in treating vitiligo with few side effects.
1 citations
,
May 2019 in “Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism” Intravenous calcium therapy is a safe and effective treatment for a rare type of rickets.
1 citations
,
January 2017 in “The Annals of Clinical and Analytical Medicine” Vitamin D receptor gene changes don't affect alopecia areata risk.
Vitamin D is crucial for skin health and managing skin diseases.
January 2022 in “International Journal of Medicine in Developing Countries” Many patients with hair loss had low iron and vitamin D levels, but thyroid issues were not common.
April 2016 in “Journal of Investigative Dermatology” Lithocholic acid helps hair growth and regeneration in alopecia by activating vitamin D receptors.
24 citations
,
November 2008 in “Arquivos Brasileiros de Endocrinologia & Metabologia” Four patients with a type of rickets and hair loss had different mutations in their vitamin D receptor gene, causing it to not work properly.
1308 citations
,
March 1998 in “Journal of bone and mineral research” The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.
277 citations
,
July 2002 in “Molecular Endocrinology” Removing part of the vitamin D receptor stops vitamin D from working properly.
271 citations
,
September 2008 in “Nutrition reviews” Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.
185 citations
,
June 2011 in “Molecular and cellular endocrinology” Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.
104 citations
,
May 2003 in “Endocrinology” Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.
37 citations
,
June 2018 in “Clinical and Experimental Medicine” People with alopecia areata often have lower vitamin D levels and more inflammation, suggesting vitamin D might be involved in the condition.
37 citations
,
April 2011 in “Journal of Biological Chemistry” LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.
28 citations
,
January 2012 in “Biological & pharmaceutical bulletin” Hairless protein can both repress and activate vitamin D receptor functions, affecting gene regulation.
20 citations
,
July 2017 in “Scientific Reports” A single amino acid change in the vitamin D receptor can disrupt its function and lead to hair loss.
18 citations
,
June 2012 in “Archives of Dermatological Research” Vitamin D boosts a specific protein in skin cells linked to hair follicles.
6 citations
,
August 2020 in “Dermatology and Therapy” People with Alopecia Areata often have lower vitamin D levels, and vitamin D supplements might help treat it.
4 citations
,
July 2019 in “IOP conference series” Most young men with early gray hair have low vitamin D but normal iron levels.
3 citations
,
January 1992 in “Clinical Pediatric Endocrinology” Patients with the same vitamin D receptor mutation showed different symptoms due to other factors.
2 citations
,
November 2017 in “PloS one” Some vitamin D analogs can thicken skin and reduce pore size like a common acne treatment, with one analog also affecting skin growth factors.
Adequate vitamin D might lower, and high hair chromium might increase DNA damage in obese women.
February 2022 in “Global academic journal of medical sciences” People with alopecia areata have much lower Vitamin-D levels than healthy individuals.
3 citations
,
November 2022 in “Baghdad Journal of Biochemistry and Applied Biological Sciences” Women with PCOS have higher renin and d-dimer levels, especially if they have COVID-19.
July 2021 in “Al-Azhar Assiut Medical Journal” Low ferritin, vitamin D deficiency, and thyroid problems may contribute to hair loss in some hospital patients in Western Saudi Arabia.