15 citations
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February 2015 in “Han-gug chugsan sigpum hag-hoeji/Korean journal for food science of animal resources” Egg shell membrane hydrolysates can reduce wrinkles and improve skin health.
93 citations
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May 2002 in “Journal of Investigative Dermatology” Overexpressing thrombospondin-1 in mice skin prevents UVB-induced skin damage.
41 citations
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May 2018 in “Nutrition and healthy aging” Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.
November 2025 in “Plant Science Today” Natural anti-aging products from plants may help improve skin health.
3 citations
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June 2023 in “Journal of cosmetic dermatology” The gel with CBD and EPA reduced wrinkles, improved skin hydration and elasticity, and had strong anti-aging effects.
April 2023 in “Journal of Investigative Dermatology” Urban pollution and sun exposure speed up skin aging and wrinkle formation in Chinese women, with pollution's effects becoming significant after age 45.
52 citations
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November 2006 in “International Journal of Cosmetic Science” Different types of wrinkles need specific treatments.
5 citations
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September 2013 in “BMB Reports” BMPR1a-ECD reduces wrinkles much more effectively than retinoic acid.
November 2025 in “BMC Genomics” Wrinkled skin in Xiang pigs is linked to gene changes related to oxidative stress and the extracellular matrix.
3 citations
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September 2023 in “Skin research and technology” New treatments for skin damage from UV light using stem cells and their secretions show promise for skin repair without major risks.
Shh and Dhh affect skin development and can cause tumors, while Ihh does not.
September 2017 in “Journal of Investigative Dermatology” Aging causes sweat glands to shrink and move upward, leading to less elastic skin and more wrinkles.
September 2022 in “The Egyptian Journal of Hospital Medicine” Microneedling is an effective, safe, and affordable method to treat skin conditions like scars and wrinkles.
January 2026 in “Molecular Nutrition & Food Research” Gynostemma pentaphyllum and Damulin B help prevent skin aging from UVB by reducing oxidative stress and improving skin health.
Heated radish extract may help lighten skin and reduce aging signs.
April 2018 in “Journal of Investigative Dermatology” Fetuin A, Anigozanthos Flavidus extract, and Ovol2 affect wound healing and skin regeneration.
11 citations
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January 2005 in “Brazilian Journal of Medical and Biological Research” Hairless USP mice have enlarged skin cysts as they age.
April 2018 in “Journal of Investigative Dermatology” Fetuin A may increase collagen production and promote scarring.
108 citations
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January 2003 in “Journal of Cosmetic Dermatology” Wrinkles form due to structural skin changes and vary in type and treatment response.
4 citations
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July 2024 in “Cureus” The treatment improved neck wrinkles and skin laxity.
74 citations
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June 2018 in “Cell death and disease” Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.
March 2024 in “Intisari Sains Medis” PRP injections improve periorbital wrinkles and show promise as a treatment.
45 citations
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November 2017 in “Biomaterials” Researchers found a new way to create hair-growing structures in the lab that can grow hair when put into mice.
April 2018 in “Journal of Investigative Dermatology” Anigozanthos Flavidus flower extract helps regenerate skin and reduce wrinkles.
January 2016 in “Georg Thieme Verlag eBooks” Facelift surgery has evolved to focus on natural results and safety, with patient selection and postoperative care being key to success.
6 citations
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July 2017 in “Plastic surgical nursing : official journal of the American Society of Plastic and Reconstructive Surgical Nurses” Microneedling is effective for skin rejuvenation and various skin issues, but more research is needed to confirm its safety and effectiveness.
June 2023 in “Research Square (Research Square)” Hyaluronic acid and polycaprolactone improve skin regeneration, with polycaprolactone having a stronger effect on healing and tissue repair.
10 citations
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August 2024 in “Clinical Cosmetic and Investigational Dermatology” Natural ingredients may help reduce skin aging by protecting cells and boosting collagen.
11 citations
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September 2007 in “Advances in therapy” INVERSION Femme supplement helped women lose weight, reduce hair loss, and improve skin and nail health.
2 citations
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June 2025 in “Cosmetics” Rosehip oil reduces wrinkles and UV spots and may have antimicrobial benefits.