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Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

Dried blood spots can be as stable as frozen liquid samples for storing certain metabolites.

The NUDT15 gene variant causes severe side effects from azathioprine in some Indian patients.

Beard hair follicles convert testosterone to 5α-dihydrotestosterone most intensively.

Near-infrared probes can safely and effectively image cysteine protease activity for disease diagnosis.

DGAT1 enzyme helps make diacylglycerols, waxes, and retinyl esters.

A new gene mutation causes hereditary coproporphyria with reduced enzyme activity.

Engineered bacteria can deliver antioxidants to protect skin.

The enzyme myo-inositol oxygenase is not linked to the cause of polycystic ovarian syndrome.

Minoxidil's absorption is too variable for it to be a reliable reference drug.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Some synthesized compounds were more effective than Finasteride in reducing prostate cancer cell growth and androgen levels.

Increased ODC activity leads to skin tumors by recruiting stem cells, not by toxic byproducts.

The research found enzymes in Stephania epigaea that help make cepharanthine.

Finasteride increases P-glycoprotein activity in the liver and kidney.

Testing for the NUDT 15 variant is crucial before starting azathioprine, especially in Asians.

New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.

The rs1128977 gene variant may affect cholesterol and body measurements.

Certain polyphenols may help treat skin pigmentation disorders.

New compounds were made that effectively block a specific enzyme related to androgen conditions.

ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.

Mice without certain skin enzymes have faster hair growth and bigger eye glands.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

GI197111X is best dissolved in Capmul MCM for trials.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Certain genetic variants reduce enzyme activity, contributing to non-classic congenital adrenal hyperplasia.

Overexpressing SSAT enzyme reduces prostate tumor growth in mice.

Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.