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GlossaryStratum Corneum

outermost skin layer composed of dead, keratinized cells

The Stratum Corneum, also known as the Horny Layer, is the outermost layer of the epidermis, consisting of dead, flattened skin cells that are rich in keratin. This layer acts as a primary barrier to protect underlying tissues from infection, dehydration, and mechanical stress, playing a crucial role in maintaining skin hydration and overall health.

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Research

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research 火针联合水杨酸对痤疮患者皮肤屏障功能及微生态的影响（The impact of fire needle therapy combined with salicylic acid on the skin barrier function and microecology of patients with acne）

January 2025 in “中医药研究与应用（Research and application of traditional Chinese medicine）”

Combining fire needle therapy with salicylic acid may improve skin barrier and balance skin bacteria in acne patients.

research Does dry skin indicate defective epidermal permeability barrier?

October 2022 in “Chinese Journal of Dermatology”

Dry skin does not mean the skin's protective barrier is broken; it's often due to a lack of natural skin moisturizers.

research Novel Placenta-Derived Liquid Product Suitable for Cosmetic Application Produced by Fermentation and Digestion of Porcine or Equine Placenta Using Lactic Acid Bacterium Enterococcus faecalis PR31

5 citations , January 2024 in “Fermentation”

The new placenta-derived liquid improves skin moisture better than traditional extracts.

research Glycerol Regulates Stratum Corneum Hydration in Sebaceous Gland Deficient (Asebia) Mice

216 citations , May 2003 in “Journal of Investigative Dermatology”

Glycerol is essential for skin hydration in mice without sebaceous glands.

Effect of Hair Loss Management with Aroma Scalp Massage on Hair and Scalp Conditions

research Effect of a Hair Loss Management Concurrently Incorporating Aroma Scalp Massage on Hair and Scalp Conditions

2 citations , June 2024 in “Journal of the Korean Society of Cosmetology”

Aroma scalp massage improved scalp condition and satisfaction but not hair thickness or density.

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community Tretinoin can make it worse!!!

in Chat 7 upvotes 3 years ago

Tretinoin may enhance minoxidil's effectiveness for those not responding to minoxidil alone, but it could reduce efficacy for some who are already responding to minoxidil. Tretinoin requires careful use, including skin moisturizing and sun protection due to increased sensitivity.

community Creating Custom Topicals: A Guide (2025 Edition)

in Research/Science 27 upvotes 9 months ago

Creating custom topical treatments for hair loss using minoxidil, finasteride, and RU58841. It includes recipes and instructions for home preparation, focusing on cost savings and customization.

community Finasteride can revive up to 7 year old dead hair

in Research/Science 188 upvotes 1 year ago

Finasteride and minoxidil can revive hair dormant for up to 7 years, with microneedling enhancing regrowth. Users report significant hair regrowth even after long periods of baldness.

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