Current Options and Treatment Strategies for Alopecia Areata in Comorbidity with Atopic Diseases

The study evaluates current treatment options for alopecia areata (AA) associated with atopic diseases (AD), highlighting the "atopic type" of AA. It reviews 78 publications and presents two clinical cases. In one case, a patient on dupilumab showed improvement in universal AA, atopic dermatitis (AD), and asthma. Another patient with AD and subtotal AA achieved partial remission with combined therapy, including UVB 311 nm and antihistamines. The study suggests that phototherapy and antihistamines, used for AD, may aid hair regrowth in AA. For systemic therapy, JAK inhibitors like baricitinib, upadacitinib, and abrocitinib are recommended. Dupilumab is suggested for AA with severe AD and respiratory allergies, even in young children. The treatment strategy should aim to reduce pharmacological load and improve quality of life, considering disease severity and patient age.