The Healing Potential Of Platelet-Rich Plasma: Advances In Preparation Methods, Biomedical Applications, And Emerging Challenges

November 2025 in “ Advanced Therapeutics ”

Mustafijur Rahman, Md Golam Nur, Tanvir Mahady Dip, Nusrat Binta Hossain, Rajiv Padhye, Shadi Houshyar

platelet-rich plasma PRP growth factors cytokines regenerative medicine tissue repair

TLDR Platelet-rich plasma can aid tissue repair but faces challenges in standardization.

The review discusses the therapeutic potential of platelet-rich plasma (PRP) in regenerative medicine, highlighting its ability to enhance tissue repair and regeneration through the release of growth factors and cytokines. PRP has expanded from its initial use in managing thrombocytopenia to applications in dermatology, neurology, orthopedics, nerve regeneration, dentistry, and skin aging treatment. Despite its promise, PRP therapy faces challenges due to inconsistencies in preparation methods, which affect its standardization and clinical efficacy. The review provides a multidisciplinary overview of recent advancements in PRP preparation and addresses issues related to standardization, ethical considerations, and future research directions, aiming to improve clinical outcomes and broaden PRP's therapeutic use.

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PRP therapy shows promise in healing and tissue repair across various medical fields but needs more research for standardization and optimization.

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research Randomized Control Trial to Study the Efficacy and Safety of Platelet-Rich Plasma as Intraoperative Holding Solution in Hair Restoration Surgery: A Pilot Study

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Using platelet-rich plasma in hair restoration surgery significantly improves hair density after 6 months and is safe to use.

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17 citations , March 2021 in “Expert Opinion on Biological Therapy”

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24 citations , January 2021 in “Dermatologic Therapy”

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58 citations , January 2020 in “International Journal of Molecular Sciences”

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Semantic ratio: 80%