research Androgen- and Estrogen-Secreting Adrenal Cancers
Rare adrenal cancers that secrete androgens or estrogens have a poor prognosis and are treated primarily with surgery.
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research Oral Pigmentation as a Sign of Addison’s Disease: A Brief Reappraisal
Oral pigmentation can be a sign of Addison's disease.
research Demethylation of methionine and keratin damage in human hair
Copper and iron cause keratin damage in hair by converting methionine to homocysteine.
research The Role of Cytochrome P-450 in Dermatology
Cytochrome P-450 enzymes in the skin help break down various substances and could be targeted to treat skin conditions.
research Cutaneous transcriptome analysis in NIH hairless mice
Key genes linked to hair growth and cancer were identified in hairless mice.
research Issues in the Treatment of Epilepsy
Treating epilepsy is complex, requiring careful drug choice and patient adherence to manage seizures and side effects.
research NF-κB in biology and targeted therapy: new insights and translational implications
NF-κB signaling is crucial in many diseases and can be targeted for new treatments.
research Structure and Development of the Skin and Cutaneous Appendages
Understanding skin structure and development helps diagnose and treat skin disorders.
research Epithelial–mesenchymal transition in cutaneous fibrosis disease: from mechanisms to therapy
EMT plays a key role in skin fibrosis and offers new therapy targets.
research 5α-Reductase underscores the development of pectoral fin breeding tubercles in zebrafish
The development of breeding tubercles in male zebrafish relies on a specific enzyme that processes hormones.
research NAD⁺ Biology in Ageing and Chronic Disease: Mechanisms and Evidence across Skin, Fertility, Osteoarthritis, Hearing and Vision Loss, Gut Health, Cardiovascular–Hepatic Metabolism, Neurological Disorders, and Muscle
Restoring NAD⁺ may help with aging and chronic diseases, but more research is needed.
research Inhibition of autophagy-lysosomal function exacerbates microglial and monocyte lipid metabolism reprograming and dysfunction after brain injury
Blocking autophagy worsens lipid buildup and dysfunction in brain cells after injury.
research Anthocyanins: Natural Pigments with Multifaceted Health Benefits for Humans
Anthocyanins in berries and purple veggies offer health benefits but need better processing for full use.
research Differential plasma proteome analysis reveals key proteins associated with insulin resistance in acne vulgaris patients
C4BPA protein may link acne severity and insulin resistance.
research Identification and single-cell analysis of prognostic genes related to mitochondrial and neutrophil extracellular traps in bladder cancer
Six key genes can predict bladder cancer outcomes and may serve as prognostic biomarkers.
research AP-2α/AP-2β transcription factors are key regulators of epidermal homeostasis
AP-2α and AP-2β proteins are essential for healthy adult skin and hair.
research T cell and bacterial microbiota interaction at intestinal and skin epithelial interfaces
T cells and bacteria in the gut and skin help maintain health and protect against disease.
research Proteins observed in scalp hair from preschool children
Mothers have more hair proteins than their children, with age-related differences in protein patterns, and some proteins in hair could indicate early childhood development.
research In-silico studies in herbal drugs: A review
Computational methods can speed up and improve the development and safety of herbal drugs.
research Apply directly to the forehead: Holmes, Nana, and hennapecia
Henna mixed with PPD can cause skin reactions, scarring, and a specific type of baldness, and needs more research to understand these effects.
research The murine hair follicle is a melatonin target
Melatonin directly affects mouse hair follicles and may influence hair growth.
research Chemotherapy and Cutaneous Drug Reactions
Chemotherapy can cause skin side effects that affect patients' lives, but they can be managed to avoid interrupting cancer treatment.
research Chapter 6 Fetal Skin Wound Healing
Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.
research Flavonoids and Nod Factors: Importance in Legume-Microbe Interactions and Legume Improvement
Flavonoids and Nod factors are key for legume plant growth and could help in sustainable farming.
research Approach to androgen excess in women: Clinical and biochemical insights
The document concludes that a systematic approach is crucial to identify causes of androgen excess in women beyond the most common cause, Polycystic ovary syndrome (PCOS).
research Study on the Efficacy and Potential Mechanism of Topical Shen Bai Hair Growing Decoction against Androgenetic Alopecia Based on Ultrahigh Performance Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry and RNA-seq
The Shen Bai Hair Growing Decoction may help treat hair loss by promoting hair growth and reducing inflammation.
research Dermal white adipose tissue development and metabolism: The role of transcription factor Foxn1
Foxn1 is important for fat development, metabolism, and wound healing in skin.
research Society for Endocrinology Clinical Practice Guideline for the Evaluation of Androgen Excess in Women
Evaluate and manage androgen excess in women with a systematic approach, considering both physical and psychological impacts.
research Corticotropin releasing factor-1 receptor antagonism associated with favorable outcomes of male reproductive health biochemical parameters
Blocking CRF1 receptors improved male hormone levels and reduced testicular tumor size in men with a specific adrenal condition.
research Effect of 5-alpha reductase inhibitors in animal models of Parkinson’s disease
5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.