The conclusion is that there's a link between high testosterone levels, insulin resistance, and certain skin conditions, regardless of obesity.
56 citations
,
October 1983 in “Archives of Dermatology” Some women with acne have higher levels of free testosterone, which might suggest using hormonal treatments for acne.
May 2022 in “Endocrine Abstracts” Cyproterone acetate therapy improved hair loss and reduced testosterone levels in a menopausal woman.
January 2004 in “DOAJ (DOAJ: Directory of Open Access Journals)” Men with androgenetic alopecia do not have elevated DHEA-S levels.
78 citations
,
March 1989 in “The Journal of Clinical Endocrinology & Metabolism” High-dose androgen therapy can help manage certain types of androgen resistance.
January 1978 in “Enlighten: Theses (The University of Glasgow)” Inhibiting testosterone 5alpha-reductase may help treat benign prostatic hyperplasia.
January 2024 in “Journal of the Endocrine Society” The research found that measuring androgens in urine can give extra information about body metabolism and is linked to androgen levels in the blood, especially in young girls.
October 1984 in “Kidney international” The patient had complex urinary tract issues and ambiguous genitalia, with physical features suggesting a hormonal imbalance.
56 citations
,
December 2002 in “The Journal of Clinical Endocrinology & Metabolism” Human bone cells mainly produce a type 1 enzyme that may help regulate bone health.
22 citations
,
September 2024 in “Human Reproduction Update” Androgen measurement helps diagnose PCOS, but accuracy varies, needing standard methods.
235 citations
,
September 2004 in “The Journal of urology/The journal of urology” Drugs that block DHT production can effectively treat enlarged prostate and improve urinary issues with some sexual side effects.
1 citations
,
January 1996 in “Gynecological endocrinology” Non-invasive imaging helped diagnose a woman's severe hormone imbalance and diabetes, and medication successfully treated her condition.
89 citations
,
February 1993 in “Journal of Medicinal Chemistry” New compounds called benzoquinolinones may treat conditions linked to excess DHT.
56 citations
,
November 2007 in “Molecular and cellular endocrinology” Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.
July 2016 in “International journal of biomedical research” Family history and elevated DHEA-S levels are linked to more severe hair loss.
12 citations
,
September 2014 in “Bone” A vitamin D receptor mutation causes rickets and affects immune responses.
May 2023 in “GLOBAL JOURNAL FOR RESEARCH ANALYSIS” Early onset hair loss is linked to low vitamin D, but severity isn't related to vitamin D levels.
January 2002 in “HAL (Le Centre pour la Communication Scientifique Directe)” The enzyme system in hair follicles is similar to the liver's and is inhibited by certain substances.
57 citations
,
January 1986 in “The Prostate” The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.
11 citations
,
September 2020 in “Steroids” A new method accurately measures steroid hormones in a few hair strands and could help study chronic stress and hair loss.
4 citations
,
September 2024 in “Frontiers in Endocrinology” Serum steroid profiling, especially 11-deoxycortisol, helps distinguish between adrenocortical carcinoma and adenoma, considering sex and functional status.
November 2018 in “Endocrine Abstracts” A woman's high testosterone levels were caused by a rare ovarian tumor, not the initially diagnosed condition.
2 citations
,
September 2021 Patients with alopecia areata may have lower vitamin D levels than healthy people.
3 citations
,
December 2000 in “Journal of the Royal Society of Medicine” Antiandrogen therapy may be beneficial for women with hidradenitis suppurativa.
10 citations
,
September 2015 in “PLoS ONE” New mutations in the VDR gene cause vitamin D-resistant rickets without hair loss.
18 citations
,
May 1992 in “American Journal of Biological Anthropology” Higher androgen levels do not cause baldness in men.
26 citations
,
March 1981 in “Clinical Endocrinology” Oestrogen does not affect adrenal androgen levels in children and adolescents.
September 2024 in “Journal of Clinical and Translational Endocrinology Case Reports” Biotin can interfere with lab tests, causing misdiagnosis.
38 citations
,
October 1996 in “Dermatologic Clinics” Certain hormone treatments can improve acne and related conditions in women.
19 citations
,
July 2013 in “The obstetrician & gynaecologist” The document concludes that careful evaluation is needed to diagnose PCOS correctly due to similar symptoms in other conditions, and accurate testosterone level measurement is crucial.