research Paclitaxel-loaded star-shaped copolymer nanoparticles for enhanced malignant melanoma chemotherapy against multidrug resistance
The new nanoparticles could improve melanoma treatment by working better than current options.
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270-300 / 1000+ resultsresearch Smart Responsive Microneedles for Controlled Drug Delivery
Smart microneedles can deliver drugs painlessly and accurately for diseases like diabetes and tumors.
research Chemical profiles and pharmacological attributes of Apis cerana indica beehives using combined experimental and computer-aided studies
Beehive extracts may help with anxiety, depression, and inflammation.
research Atroposelective Synthesis of Biaryl N‐Oxides via Cu‐Catalyzed De Novo Heteroaromatic N‐Oxide Ring Formation
A new method efficiently creates biaryl N-oxides with potential for cancer treatment and drug development.
research Advancing Design Strategy of PROTACs for Cancer Therapy
PROTACs show promise for cancer treatment, but designing them effectively is challenging.
research Advancing mitochondrial therapeutics: Synthesis and pharmacological evaluation of pyrazole-based inhibitors targeting the mitochondrial pyruvate carrier
New pyrazole-based inhibitors show promise for treating metabolic diseases and other conditions.
research Recent Insights in Multi‐Target Drugs in Pharmacology and Medicinal Chemistry
Multitarget drugs are needed to better treat complex diseases.
research Bioinspired Polymers: Transformative Applications in Biomedicine and Regenerative Medicine
Bioinspired polymers are promising for advanced medical treatments and tissue repair.
research Application of 3D Bioprinting Technology for Tissue Regeneration, Drug Evaluation, and Drug Delivery
3D bioprinting is useful for making tissues, testing drugs, and delivering drugs, but needs better materials, resolution, and scalability.
research Ex Vivo Treatment with Allogenic Mesenchymal Stem Cells of a Healthy Donor on Peripheral Blood Mononuclear Cells of Patients with Severe Alopecia Areata: Targeting Dysregulated T Cells and the Acquisition of Immunotolerance
Using healthy donor stem cells can potentially calm overactive immune cells and reduce inflammation in severe hair loss patients, offering a possible treatment method.
research ENZYMES
Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.
research A Comprehensive Review of Acne Treatments: Unpacking the Chemical Structures and Effective Bioactive Compounds
Understanding acne medication chemistry helps doctors treat acne better.
research Chemical Composition and Bioactive Properties of Camellia oleifera C. Abel Leaves
Camellia oleifera leaves have compounds beneficial for cosmetics and medicine.
research In-Depth Exploration of Chemical Constituents from Justicia procumbens L. Through UHPLC-Q-Exactive Orbitrap Mass Spectrometry
132 compounds were found in Justicia procumbens L., including 77 new ones.
research The Extract of Periplaneta americana (L.) Promotes Hair Regrowth in Mice with Alopecia by Regulating the FOXO/PI3K/AKT Signaling Pathway and Skin Microbiota
Periplaneta americana extract helps hair regrowth in mice with alopecia.
research Dynamic immunomodulatory nanoarchitectonics: Rewiring tissue regenerative microenvironment via intelligent regulation
Nanotechnology can improve tissue healing by controlling immune responses.
research Composition, structural features, and multifunctional properties of extracellular polysaccharides from the non-toxic green alga Parachlorella sp.
The green alga Parachlorella sp. has potential for use in cosmetics and health products due to its antioxidant, anti-hypertensive, and hair growth properties.
research Bioactive Compound-Loaded Nanocarriers for Hair Growth Promotion: Current Status and Future Perspectives
Nanocarriers with plant extracts show promise for safe and effective hair growth treatment.
research Active Compounds with Medicinal Potential Found in Maxillariinae Benth. (Orchidaceae Juss.) Representatives—A Review
Maxillariinae orchids contain 62 compounds with potential health benefits, including treating skin conditions and diseases like cancer and diabetes.
research Enzymes
Enzymes play crucial roles in metabolism, health, and disease management.
research Effects of Microwave-Assisted Opuntia humifusa Extract in Inhibiting the Impacts of Particulate Matter on Human Keratinocyte Skin Cell
Microwave-assisted Opuntia humifusa extract protects skin cells from pollution damage.
research Characterization and In Vivo Assay of Allantoin-Enriched Pectin Hydrogel for the Treatment of Skin Wounds
The hydrogel significantly speeds up skin wound healing.
research Fármacos de uso frecuente en dermatología como terapia para COVID-19
Common dermatology drugs were considered but are controversial for COVID-19 treatment.
research The Role of Natural Hydrogels in Enhancing Wound Healing: From Biomaterials to Bioactive Therapies
Natural hydrogels can improve wound healing but face challenges in becoming widely used in clinics.
research Microneedle-Based Technologies for Long-Acting Transdermal Drug Delivery in Wearable Devices
Microneedles in wearables can deliver drugs over time but face challenges in manufacturing and safety.
research Nanoparticles for Topical Application in the Treatment of Skin Dysfunctions—An Overview of Dermo-Cosmetic and Dermatological Products
Nanoparticles improve skin treatment but need more research on safety and effectiveness.
research The JAK/STAT signaling pathway: from bench to clinic
The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
research Transdermal delivery of mixnoxidil with block copolymer nanoparticles
Smaller nanoparticles improve minoxidil delivery through hair follicles.
research Chemical Composition and Biological Activities of Essential Oils of Curcuma Species
Essential oils from Curcuma species, like turmeric, have compounds that can fight inflammation, cancer, and bacteria, and can also stimulate hair regrowth in bald males.
research Phytochemistry, pharmacological activity, and potential health benefits of Glycyrrhiza glabra
Licorice has many health benefits but should be used carefully due to possible side effects.