18 citations
,
March 2020 in “Frontiers in Neuroendocrinology” The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
8 citations
,
May 2012 in “Australasian Journal of Dermatology” January 2007 in “xPharm: The Comprehensive Pharmacology Reference”
1 citations
,
September 2016 in “Actas Dermo-Sifiliográficas” 5-alpha reductase inhibitors may cause sexual side effects, breast complications, and other health risks in men with hair loss.
June 2025 in “Turkish Journal of Dermatology” Acne patients have lower enzyme activity, suggesting oxidative stress may contribute to acne.
1 citations
,
January 2020 in “IRIS UNIMORE (University of Modena and Reggio Emilia)” Aminexil clinical 5 effectively reduces hair loss and is well-tolerated.
44 citations
,
July 1993 in “Journal of Investigative Dermatology” 4 citations
,
June 2024 in “The Kaohsiung Journal of Medical Sciences” Atg5 can promote tumors when autophagy is deficient but suppresses them under normal conditions.
March 2022 in “Research Square (Research Square)” 4-aminopyridine, a FDA-approved drug, speeds up skin wound healing and tissue regeneration.
33 citations
,
March 1994 in “PubMed” High ODC and low K1 and K10 may indicate early skin tumors in mice.
27 citations
,
April 2004 in “Biochemical and Biophysical Research Communications” Two new gene clusters important for hair formation were found on human chromosome 11.
January 2011 in “Bloomsbury Academic eBooks” February 2017 in “Cancer Research” Topical calcitriol appears safe and may reduce hair loss during chemotherapy.
September 2016 in “Journal of dermatological science” The OVOL1-OVOL2 axis is important for hair follicle differentiation and can help diagnose certain hair-related tumors.
August 2024 in “Archives of Dermatological Research” CHI3L1 and CXCL5 proteins help promote hair growth.
January 2026 in “Biochemical Pharmacology” MitoQ helps protect hair cells from damage in hair loss by boosting a protective enzyme.
March 2022 in “Journal of Maxillofacial and Oral Surgery” I'm sorry, but I can't provide a summary as I don't have the specific details about the "45th AOMSI Conference".
Dihydrotestosterone (DHT) and its active metabolites play a key role in various diseases, and the development of 5α-reductase inhibitors can help treat these conditions.
February 2013 in “Journal of The American Academy of Dermatology” Using hair loss drugs finasteride and dutasteride may cause sexual side effects.
January 2026 in “Journal of Cosmetic Dermatology” Topical 4-aminopyridine 5% does not improve hair growth in male pattern baldness.
November 2022 in “Journal of Investigative Dermatology” Low oxygen levels affect the behavior of certain proteins in human skin cells.
2 citations
,
November 2018 in “Indian Journal of Pharmaceutical Education” The developed model can predict effective 5-alpha-reductase enzyme inhibitors.
17 citations
,
October 2005 in “Journal of Biological Chemistry” Early involution in Hirosaki hairless rats' mammary glands is linked to a unique modification of STAT5A.
June 2024 in “Journal of Ayub Medical College Abbottabad” Combining PRP with Procapil is more effective for hair loss treatment than PRP alone.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” YAP1 is important for skin regeneration and may affect skin disorder treatments.
1 citations
,
March 2023 in “Science Translational Medicine” Blocking a certain signal in the gp130 receptor can improve tissue healing and lessen osteoarthritis symptoms.
October 2021 in “Skin appendage disorders”
10 citations
,
July 2022 in “Journal of Medicinal Chemistry” Adding a second method to PROTACs could improve cancer treatment.
53 citations
,
June 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” KAP genes show significant genetic variability, but its impact on hair traits is unclear.
11 citations
,
October 2024 in “Cell Death Discovery” 4-aminopyridine helps heal burn wounds faster by reducing inflammation and promoting new blood vessel growth.