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Compounds 15, 20, and 25 are strong inhibitors of human steroid 5α-reductase type 2.

Triphenylphosphine oxide can increase oil production and reduce inflammation in skin cells without affecting TRPM5.

A new small peptide may help hair growth by activating a specific receptor and should be tested in humans.

New indole-based compounds, particularly cemtirestat, show promise as dual-function drugs for diabetic complications.

New pyrazole-based inhibitors show promise for treating metabolic diseases and other conditions.

The scalp fat tissue of men with hair loss shows changes in gene activity that may contribute to their condition.

Adipose-derived stem cells can be used to create cells that help grow new hair.

A new compound effectively inhibits human 5α-reductase 1.

Retinoids can help treat skin pigmentation disorders by affecting melanin production.

TCDD changes skin cell growth and keratin production in mice.

Low vitamin D in overweight teens is linked to higher leptin and lower adiponectin, affecting metabolism.

Increased energy use in Pik3r1-related insulin resistance isn't due to Ucp1 thermogenesis.

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.

Lack of 5α-Reductase type 1 can lead to insulin resistance and liver problems.

Lepidium sativum seed extracts helped reduce inflammation and improve insulin response in obese rats on a high-fat diet.

Fluphenazine and iloprost can induce hair growth.

MFN2 mutations cause mitochondrial problems, unusual fat distribution, and low leptin despite high body fat.

Adipose tissue-derived therapies show promise for improving osteoarthritis symptoms but need more research for safety and effectiveness.

Targeting adipocyte-to-mesenchymal transition could help treat fibrosis.

Lower lipin 1β in belly fat is linked to insulin resistance in people with polycystic ovary syndrome.

Blocking SCD1 in the skin with XEN103 shrinks sebaceous glands in mice.

A brominated phenoxy compound effectively inhibits a human enzyme and shows potential for clinical use.

RSPO1 could help create new diabetes treatments by increasing pancreatic β cells.

TSLP affects atopic dermatitis by increasing sebum and reducing fat through IL-4/IL-13 signaling.

3D-cultured dermal papilla cells are better at inducing hair follicles than adipose-derived stem cells.

Early diagnosis and treatment are crucial for managing Berardinelli–Seip syndrome.

Allopregnanolone and opioids together reduce stress hormone responses during pregnancy.

Androstanediol glucuronide is a reliable marker for hirsutism in women.

New nonsteroidal molecules can potentially increase dihydrotestosterone in neurons by blocking certain enzymes, without affecting prostate and seminal vesicle weight.

Exposure to certain chemicals in food and containers may increase the risk of early breast development in young girls.