research Acellular dermal matrix hydrogels promote healing of radiation-induced skin injury in a rat model
ADM hydrogels help heal radiation skin injuries.
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research Effects of dobutamine on cyclic AMP accumulation induced by the stimulation of dopamine receptors in rabbit retina in vitro
Dobutamine does not mimic dopamine at therapeutic doses but may at very high concentrations; microfilaments, not microtubules, are important for wound healing in Xenopus embryos.
research ACKR2 limits skin fibrosis and hair loss through IFN‐β
ACKR2 helps prevent skin scarring and hair loss by controlling inflammation.
research 851 The role of astrotactin2 in regulating mammalian skin polarity
Astrotactin2 affects hair follicle orientation and skin cell polarity.
research eLife Assessment: The Drosophila hematopoietic niche assembles through collective cell migration controlled by neighbor tissues and Slit-Robo signaling
Proper niche formation in Drosophila requires Slit-Robo signaling for cell migration.
research Adipose Mesenchymal Stromal Cell-Derived Exosomes Carrying MiR-122-5p Antagonize the Inhibitory Effect of Dihydrotestosterone on Hair Follicles by Targeting the TGF-β1/SMAD3 Signaling Pathway
ADSC-Exos with miR-122-5p can help treat hair loss by promoting hair growth.
research Activation of developmental signaling pathways in hematopoietic stem cell regeneration
Wnt and Notch pathways are crucial for repairing blood stem cells after damage.
research Intradermal adipocytes mediate fibroblast recruitment during skin wound healing
Fat cells help recruit healing cells and build skin structure during wound healing.
research Canonical WNT signaling promotes mammary placode development and is essential for initiation of mammary gland morphogenesis
WNT signaling is crucial for starting mammary gland development.
research Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men
Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.
research A Wnt5a-Cdc42 axis controls aging and rejuvenation of hair-follicle stem cells
Aging hair follicle stem cells can be rejuvenated by inhibiting Cdc42.
research Effects of Restraint Stress and Allopregnanolone Inhibition on Amphetamine Locomotor Sensitivity
Targeting neurosteroids may help prevent drug relapse.
research Regulation of the metabolic phenotype of human hepatocytes by glucocorticoids and androgens
Glucocorticoids reduce fat production in liver cells, while androgens increase it in females; manipulating certain enzymes can influence these effects.
research Melanocortin receptor type 2 (MC2R, ACTH receptor) expression in patients with alopecia areata
Lower MC2R expression may contribute to alopecia areata.
research Reprogramming adult dermis to a neonatal state through epidermal activation of β-catenin
Activating a protein called β-catenin in adult skin can make it behave like young skin, potentially helping with skin aging and hair loss.
research Cross-Signaling Between Hair Follicle Stem Cells And Dermal Lymphatic Vessels: A Systematic Review
Targeting hair follicle stem cell and lymphatic vessel signaling may help treat hair loss and improve wound healing.
research Cross-Signaling Between Hair Follicle Stem Cells And Dermal Lymphatic Vessels: A Systematic Review
Targeting hair follicle stem cell and lymphatic vessel signaling may help treat hair loss and improve wound healing.
research A Role for Steroid 5 alpha-reductase 1 in Vascular Remodelling During Endometrial Decidualisation
The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.
research An implication for post-transcriptional control: Reciprocal changes of melanocortin receptor type 2 mRNA and protein expression in alopecia areata
Alopecia areata may involve stress-related changes affecting hormone receptors, leading to reduced cortisol production.
research The Long-Term Effect of Doxazosin, Finasteride, and Combination Therapy on the Clinical Progression of Benign Prostatic Hyperplasia
Combination therapy of doxazosin and finasteride safely and effectively reduces benign prostatic hyperplasia progression risk.
research Comparison of finasteride (proscar®), a 5α reductase inhibitor, and various commercial plant extracts in in vitro and in vivo 5α reductase inhibition
Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.
research Preventing the Development of Complex Regional Pain Syndrome after Surgery
Preoperative pain assessment, regional anesthesia, and vitamin C can help prevent CRPS after surgery.
research Minoxidil in severe hypertension with renal failure
Minoxidil effectively lowers blood pressure without major side effects.
research Pharmacology and Pharmacokinetics of Minoxidil
Minoxidil treats high blood pressure and side effects can be managed.
research Selected Disorders of Skin Appendages—Acne, Alopecia, Hyperhidrosis
The conclusion is that acne, alopecia, and hyperhidrosis are common skin issues with various treatments available, and accurate diagnosis is key for effective management.
research Intraoperative floppy-iris syndrome and finasteride intake
Finasteride may cause floppy-iris syndrome during cataract surgery, so check patients' medical history.
research Toxicologic studies with the hypotensive agent minoxidil
Minoxidil is mostly safe, but high doses can cause electrolyte imbalances and heart issues in dogs.
research Increased levels of prostaglandin-like material in the canine blood during arterial hypotension produced by hydralazine, dihydralazine and minoxidil
These drugs raise prostaglandin-like material in dog blood, possibly causing blood vessel widening.
research Effect of minoxidil on blood pressure and hemodynamics in severe hypertension
research Validated HPTLC method for the simultaneous determination of alfuzosin, terazosin, prazosin, doxazosin and finasteride in pharmaceutical formulations
Method can accurately measure five BPH drugs at once.