research Allopregnanolone in the bed nucleus of the stria terminalis modulates contextual fear in rats
Allopregnanolone affects fear responses differently in male and female rats, possibly explaining sex differences in anxiety disorders.
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330-360 / 1000+ resultsresearch Randomized Placebo-Controlled Clinical Trial of Dutasteride for Reducing Heavy Drinking in Men
Dutasteride helps reduce heavy drinking, especially for those who drink to cope.
research Lack of Significant Association between Sex Hormone Concentrations and Atopic Dermatitis in Adolescents and Adults in Two Population-Based Studies
Sex hormones likely don't affect atopic dermatitis in adolescents and adults.
research Impact of the new corona virus (SARS-CoV-2) pandemic on climateric women’s health: websurvey
The pandemic worsened mental health and healthcare access for middle-aged women, leading to negative changes in their lifestyle.
research Understanding sex and gender disparities in COVID-19 mortality: a narrative review beyond biology
Gender and social factors, not just biology, affect COVID-19 death rates.
research Elevated DKK1 expression is an independent unfavorable prognostic indicator of survival in head and neck squamous cell carcinoma
High DKK1 levels predict worse survival in head and neck cancer.
research Depression, higher level of tension induction, and impaired coping strategies in response to stress in women with PCOS correlate with clinical and laboratory indices of hyperandrogenism and not with central obesity and insulin resistance
Women with PCOS have more depression and stress due to high androgen levels, not obesity or insulin resistance.
research Sodium Valproate Induced Alopecia: A Case Series
Sodium valproate can cause reversible hair loss in some patients.
research Brimonidine Beyond a Single Specialty: Pharmacological Profile, Dermatologic Applications, and Advances in Drug Delivery Systems
Brimonidine is effective for reducing facial redness in skin conditions and has potential for broader dermatological uses.
research Dual deficiency of melatonin and dihydrotestosterone promotes stromal cell damage and mediates prostatitis via the cGAS-STING pathway in sleep-deprived mice
Lack of sleep in mice leads to prostatitis by reducing certain hormones and activating an inflammatory pathway, which can be temporarily fixed with normal sleep.
research TRANSMEDCON 2022: E-Poster Abstracts
The document summarized various studies and case reports from TRANSMEDCON 2022, focusing on transfusion medicine and related fields. Key findings included the effectiveness of platelet-rich plasma (PRP) in treating androgenic alopecia, with 60% of patients showing improvement, particularly in males and younger individuals. Studies also highlighted the importance of antibody screening to enhance transfusion safety, with a 0.4% prevalence of red cell antibodies among 5,719 donors. Other research emphasized the need for routine antenatal antibody screening, the challenges of managing rare blood disorders, and the significance of nucleic acid testing (NAT) in detecting transfusion-transmissible infections. Overall, the abstracts underscored the importance of meticulous blood management, effective communication, and improved screening techniques to enhance transfusion outcomes and safety.
research Commonly encountered symptoms and their management in patients with cirrhosis
Cirrhosis affects quality of life with various symptoms, requiring a holistic, multidisciplinary approach for management.
research The impact of individual lifestyle and status on the acquisition of COVID-19: A case—Control study
Your lifestyle and health can affect your chances of getting COVID-19; not enough sleep, lots of exercise, and hair loss can increase risk, while washing hands, eating fruit daily, and taking vitamins A and C can lower it.
research Prevalence of depression and anxiety in women with polycystic ovary syndrome (PCOS) and associated factors in a quaternary hospital in Thailand: a cross-sectional study
Women with PCOS often have depression and anxiety, so they should be checked for these issues.
research Social rejection in minority groups and its impact on current and future mental health: a study in transgender people
Social rejection can harm long-term mental health in transgender individuals.
research Hair Cortisol as a Biomarker of Chronic Stress in Community-Dwelling Adults With Longstanding Multiple Sclerosis
Hair cortisol levels don't reliably indicate chronic stress in people with multiple sclerosis.
research Proposal for Clinical Classification of Cutaneous Manifestations in Covid-19 and in Post Vaccination Against Sars-Cov-2: An Observational Study
Most skin issues were due to COVID-19, with some caused by vaccines or treatments, and were categorized into five types.
research Proopiomelanocortin (POMC) and Psychodermatology
Psychological stress can worsen skin conditions like psoriasis and acne.
research Androgen-Dependent Beard Dermal Papilla Cells Secrete Autocrine Growth Factor(s) in Response to Testosterone Unlike Scalp Cells
Beard cells, unlike scalp cells, produce growth factors in response to testosterone, which may explain differences in hair growth.
research Psychological and psychiatric characterization of various groups of drugs users
Different drugs are linked to specific mental health issues.
research Trailing the Path to Preventive Oncology
Preventing cancer involves lifestyle changes, vaccinations, early screening, and understanding cancer's molecular basis.
research Mechanistic Insights on Dyspepsia Modulation by Salvia rosmarinus Through Network Pharmacology, Molecular Docking, and Molecular Dynamics
Rosemary may help reduce dyspepsia and gastric cancer risk.
research Unhealthy lifestyle and the risk of metabolic syndrome - the Romanian experience
An unhealthy lifestyle increases the risk of metabolic syndrome.
research Effects of Curcumin and Its Different Formulations in Preclinical and Clinical Studies of Peripheral Neuropathic and Postoperative Pain: A Comprehensive Review
Curcumin shows promise in reducing pain and inflammation, but more research is needed.
research Sex Differences in Animal Models of Sodium-Valproate-Induced Autism in Postnatal BALB/c Mice: Whole-Brain Histoarchitecture and 5-HT2A Receptor Biomarker Evidence
Male mice are more susceptible to autism-like changes from valproic acid than female mice.
research Combined drug triads for synergic neuroprotection in retinal degeneration
Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.
research Analgesic Effect of Human Placenta Hydrolysate on CFA-Induced Inflammatory Pain in Mice
Human placenta hydrolysate reduces inflammatory pain and nerve damage in mice.
research Sex Differences in Opioid-Mediated Effects: Role of Androgens
Men and women react differently to opioids, with hormones potentially influencing these differences.
research Biotin and biotinidase deficiency
Biotin and biotinidase are essential to prevent health issues, and deficiencies require lifelong supplementation.
research Defining the Cellular Environment in the Organ of Corti following Extensive Hair Cell Loss: A Basis for Future Sensory Cell Replacement in the Cochlea
The conclusion is that genetic differences affect how the cochlea heals after hair cell loss, which may challenge the creation of hearing loss treatments.