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GlossaryAlanine Aminotransferase

enzyme indicating liver health, also known as ALT

Alanine Aminotransferase (ALT), also known as Serum Glutamate Pyruvate Transaminase (SGPT), is an enzyme primarily found in the liver. It plays a crucial role in converting alanine, an amino acid, into pyruvate, which is essential for energy production. Elevated levels of ALT in the blood can indicate liver damage or disease, making it a valuable marker in diagnosing liver conditions.

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research [Visual field defect in a patient given sodium valporate then carbamazepine: possible effect of aminotransferase inhibition].

1 citations , April 2002 in “PubMed”

Anti-epileptic drugs may cause visual and hair side effects due to enzyme inhibition, especially in genetically predisposed individuals.

research The retarded hair growth ( rhg ) mutation in mice is an allele of ornithine aminotransferase ( Oat )

9 citations , January 2014 in “Molecular Genetics and Metabolism Reports”

The rhg mutation in mice affects the Oat gene, causing hair growth issues and other symptoms.

Variations in Alanine Aminotransferase Levels Within the Normal Range Predict Metabolic and Androgenic Phenotypes in Women of Reproductive Age

research Variations in alanine aminotransferase levels within the normal range predict metabolic and androgenic phenotypes in women of reproductive age

8 citations , October 2010 in “Scandinavian Journal of Clinical & Laboratory Investigation”

Normal-range ALT levels can indicate metabolic and hormonal imbalances in young women.

Single Nucleotide Polymorphisms Associated with Elevated Alanine Aminotransferase in Patients Receiving Asunaprevir Plus Daclatasvir Combination Therapy for Chronic Hepatitis C

research Single nucleotide polymorphisms associated with elevated alanine aminotransferase in patients receiving asunaprevir plus daclatasvir combination therapy for chronic hepatitis C

2 citations , July 2019 in “PLOS ONE”

Certain genetic variations are linked to higher liver enzyme levels in patients treated for chronic hepatitis C with specific drugs.

research RETRACTED: Ascertaining the Influence of Lacto-Fermentation on Changes in Bovine Colostrum Amino and Fatty Acid Profiles

2 citations , October 2023 in “Animals”

Lacto-fermentation changes amino acid profiles in bovine colostrum, but results are inconsistent.

research Need for liver evaluation in polycystic ovary syndrome

11 citations , July 2007 in “Journal of Hepatology”

Women with PCOS often have liver disease, so liver health checks are important for them.

research Pooled safety and tolerability data from four placebo-controlled teriflunomide studies and extensions

72 citations , November 2015 in “Multiple Sclerosis and Related Disorders”

Teriflunomide is safe and tolerable for treating relapsing-remitting multiple sclerosis, with manageable side effects.

research Clinical and hepatic evaluation in adult dengue patients: a prospective two-month cohort study

53 citations , December 2012 in “Revista da Sociedade Brasileira de Medicina Tropical”

Dengue symptoms and liver issues can persist for over two months, especially in men.

research Sequential Morphologic and Clinicopathologic Alterations in Dogs with Experimentally Induced Glucocorticoid Hepatopathy

48 citations , August 1981 in “American Journal of Veterinary Research”

Glucocorticoid use in dogs quickly causes liver changes and Cushing's syndrome symptoms.

research High dose interferon treatment in chronic hepatitis C.

36 citations , January 1993 in “Gut”

High-dose interferon is effective for chronic hepatitis C but often causes flu-like symptoms.

research Teriflunomide in multiple sclerosis: an update

20 citations , December 2016 in “Neurodegenerative disease management”

Teriflunomide effectively reduces relapses and disability in MS and has a manageable safety profile.

research Photosensitization Outbreak in Shorthorn Calves in Missouri

11 citations , April 1991 in “Journal of Veterinary Diagnostic Investigation”

Shorthorn calves in Missouri experienced photosensitization, causing skin issues and liver damage, but they eventually recovered.

research Optimal laboratory testing protocol for patients with acne taking oral isotretinoin

9 citations , April 2023 in “World Journal of Clinical Cases”

Test liver enzymes and triglycerides every 5-6 months, and cholesterol levels in the first two months for acne patients on isotretinoin.

research Biochemical changes and liver tissue pathology in weanling Wistar albino rats with protein-energy malnutrition (PEM).

4 citations , October 2003 in “PubMed”

Low protein diets cause severe health issues in rats, but high protein diets can reverse these effects.

research Nonalcoholic fatty liver disease in young adult Egyptian women with polycystic ovary syndrome

3 citations , January 2013 in “Egyptian Liver Journal”

Many young Egyptian women with PCOS also have fatty liver disease, especially if they are overweight and insulin resistant.

research Clinical Manifestations of Dermatomyositis

3 citations , March 2002 in “Linchuang pifuke zazhi”

Most patients with dermatomyositis had skin rash, itching, and muscle weakness, treated mainly with prednisolone and hydroxychloroquine.

research Hepatoprotective Activity of Yellow Chinese Chive against Acetaminophen-Induced Acute Liver Injury via Nrf2 Signaling Pathway

2 citations , August 2020 in “Journal of Nutritional Science and Vitaminology”

Yellow Chinese chive extract helps protect mouse livers from damage caused by acetaminophen by activating an antioxidant pathway.

research Ingestion of minoxidil associated with elevated transaminases in the absence of ischemic hepatitis

September 2023 in “Translational medicine reports”

Minoxidil ingestion can raise liver enzyme levels.

research Early-onset Androgenetic Alopecia in Korean Patients Showed No Significant Relationship with Medical Comorbidities

January 2016 in “대한피부과학회지”

Early-onset hair loss in Koreans isn't linked to other health issues.

research Some histological and biochemical evaluation on commercial hair dyes

May 2023 in “Sokoto journal of medical laboratory science”

Commercial hair dyes can harm the skin and liver.

research Toxicity of the immune suppressant cyclosporin A in the rat

116 citations , October 1982 in “The Journal of Pathology”

Cyclosporin A is highly toxic to rats, causing severe health issues and death.

research Auxin Input Pathway Disruptions Are Mitigated by Changes in Auxin Biosynthetic Gene Expression in Arabidopsis

52 citations , June 2014 in “PLANT PHYSIOLOGY”

Arabidopsis plants adjust gene expression to maintain balance when auxin pathways are disrupted.

research Care for Adolescents With Polycystic Ovary Syndrome: Development and Prescribing Patterns of a Multidisciplinary Clinic

14 citations , March 2021 in “Journal of Pediatric and Adolescent Gynecology”

In teens with Polycystic Ovary Syndrome and obesity, issues related to metabolism, skin, and mental health are common, and a clinic with various specialists can provide care for most of these problems.

research [Hypothyroid myopathy in a young adult].

2 citations , September 1993 in “PubMed”

Levothyroxine treatment fully cured the young man's hypothyroid symptoms.