695 citations
,
October 2011 in “Cell stem cell” Low oxygen areas help maintain and protect blood stem cells by using a simple sugar breakdown process for energy and managing their activity levels.
502 citations
,
February 2008 in “The Journal of Clinical Endocrinology & Metabolism” Treat significant hirsutism with medication and hair removal; use birth control pills first, adding antiandrogens if needed.
186 citations
,
February 2015 in “Frontiers in Neuroscience” Testosterone affects brain behavior in complex and varied ways.
98 citations
,
November 1999 in “Dermatology Online Journal” IGF-1 can boost hair growth by promoting cell growth and preventing cell death.
89 citations
,
March 2001 in “Endocrine practice” The guidelines help doctors diagnose and treat hormone-related disorders in women.
59 citations
,
September 2003 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Epitestosterone may counteract testosterone's effects and has roles in body processes like prostate growth and hair distribution.
58 citations
,
November 2018 in “Cochrane library” Oral isotretinoin may slightly improve acne but increases the risk of side effects like dry lips and skin; more research is needed to understand its full risks and benefits.
53 citations
,
July 2014 in “American Journal of Physiology-Endocrinology and Metabolism” Testosterone boosts red blood cell production and changes iron metabolism without needing dihydrotestosterone.
46 citations
,
June 2015 in “American Journal Of Pathology” Diabetes causes lasting cell dysfunctions, leading to serious complications even after blood sugar is controlled.
42 citations
,
July 2021 in “Frontiers in Medicine” Proxalutamide significantly lowered hospital admissions for male COVID-19 patients compared to a placebo.
40 citations
,
November 2019 in “Frontiers in Endocrinology” Metabolic Syndrome is linked to several skin conditions, and stem cell therapy might help treat them.
39 citations
,
April 2019 in “The journal of immunology/The Journal of immunology” Malt1 protease is essential for regulatory T cell function and could be targeted to boost antitumor immunity.
35 citations
,
July 2022 in “Frontiers in Cell and Developmental Biology” Proper mTOR signaling is crucial for healthy skin and preventing skin diseases.
34 citations
,
April 2023 in “Climacteric” Gender-affirming hormone therapy affects health risks and requires careful management, especially as transgender individuals age.
34 citations
,
January 2022 in “Human Reproduction Open” PRP injections did not significantly improve ovarian function in women with low ovarian reserve.
29 citations
,
March 2010 in “Cancer epidemiology” Men who start losing hair at age 30 may have a lower risk of prostate cancer.
27 citations
,
February 2023 in “Frontiers in Cell and Developmental Biology” WNT10B is important for body functions and linked to diseases like osteoporosis, obesity, and cancer.
26 citations
,
July 2012 in “Endocrine Connections” Mitotane changes steroid breakdown, affecting cortisol availability.
26 citations
,
June 2011 in “Molecular Medicine” Progesterone significantly reduces neuroblastoma tumor growth without harming healthy cells.
24 citations
,
December 2023 in “Gels” 3D-printed hydrogels show promise in medicine but face challenges in resolution, cell viability, cost, and regulations.
22 citations
,
February 2018 in “International Journal of Pharmacy and Pharmaceutical Sciences” Peperomia pellucida shows promise for developing new therapeutic drugs.
21 citations
,
January 2023 in “International Journal of Molecular Sciences” S100A6 protein is linked to disease progression, especially in cancers.
21 citations
,
January 2017 in “MethodsX” Methanol is better than isopropanol for washing grizzly bear hair to measure cortisol.
20 citations
,
March 2022 in “Journal of clinical medicine” Nearly half of the studied men with long COVID had low testosterone, including younger men.
19 citations
,
December 2021 in “Endocrine Reviews” There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.
17 citations
,
January 2025 in “Journal of Nanobiotechnology” Bacterial extracellular vesicles could revolutionize regenerative medicine but need safety improvements.
17 citations
,
January 2020 in “The World Journal of Men's Health” Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.
17 citations
,
December 1997 in “Transplantation” Tacrolimus can cause hair loss in kidney transplant patients.
15 citations
,
April 2025 in “Journal of Clinical Medicine” Higher platelet doses in PRP therapy improve outcomes for musculoskeletal issues.
14 citations
,
May 2012 in “Endocrine Research” The same hormone can affect gene expression differently in various tissues, which could lead to new treatments for conditions like hair loss.