Azelaic acid helps with skin pigmentation issues, but its full effects are not completely understood.
45 citations
,
January 2020 in “International Journal of Molecular Sciences” Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.
58 citations
,
March 2011 in “Pflügers Archiv für die gesamte Physiologie des Menschen und der Tiere/Pflügers Archiv” Hormones and signaling pathways control sebaceous gland function and could help treat acne.
August 2023 in “Drug Design Development and Therapy” Minoxidil may work for hair loss by reducing androgen sensitivity and altering hormone-related enzymes.
6 citations
,
July 2024 in “Heliyon” Steroid 5α-reductase evolved from protists and diversified in eukaryotes, with specific roles in mammals and plants.
July 2025 in “International Journal of Molecular Sciences” Blocking CXCL12 can reverse hair loss and fibrosis in androgenetic alopecia.
2 citations
,
September 2025 in “Future Journal of Pharmaceutical Sciences” Lupeol shows promise for hair growth but needs better absorption and safety testing.
35 citations
,
August 2021 in “BMC Medical Genomics” Certain metabolites may help diagnose and predict polycystic ovary syndrome.
July 2023 in “JAAD International” Two drugs, finasteride and minoxidil, are approved for hair loss treatment, but new therapies are being developed.
6 citations
,
August 2024 in “The Journal of Dermatology” Ozenoxacin reduces sebum production, helping manage acne.
19 citations
,
July 2005 in “Steroids” Testosterone increases 3α-androstanediol levels, which can be blocked by finasteride.
7 citations
,
September 2022 in “Communications biology” Omega-6 fats in certain cells boost male hormone production.
514 citations
,
February 2011 in “International journal of women's health” Different treatments for PCOS focus on the specific symptoms, with weight loss and lifestyle changes being important.
September 2023 in “Animals” Genes linked to wool fineness in sheep have been identified.
104 citations
,
June 2020 in “Journal of Endocrinology” Hyperandrogenism and insulin resistance in PCOS-like rats can lead to pregnancy complications due to increased cell death in the uterus and placenta.
6 citations
,
October 2014 in “Experimental Dermatology” Prostaglandins and the enzyme AKR1C3 could play a role in skin cancer and hair loss, and further research is needed to understand these mechanisms.
5 citations
,
May 2024 in “Molecules” Glycyrrhetinic acid from licorice may help treat acne by reducing inflammation and oil production.
3 citations
,
December 2022 in “npj Regenerative Medicine” HSPGs help control stem cell behavior, affecting hair growth and offering a target for hair loss treatments.
January 2026 in “Cosmetics” The fermented solution from Platycladus orientalis leaves may boost hair growth and reduce inflammation.
June 2025 in “Microorganisms” Microbial imbalances in hair follicles may contribute to hair loss, especially in women.
June 2024 in “Computational and Structural Biotechnology Journal” Multi-omics techniques help understand the molecular causes of androgenetic alopecia.
June 2024 in “Ecotoxicology and Environmental Safety” Finasteride harms Daphnia magna's reproduction, growth, and metabolism.
October 2023 in “IntechOpen eBooks” Genes and epigenetic changes are important in the development of Polycystic Ovary Syndrome.
24 citations
,
October 2012 in “The International Journal of Biochemistry & Cell Biology” Testosterone protects female heart cells from stress by activating estrogen receptors.
9 citations
,
December 2022 in “Genes” CNVs influence hair length in Tianzhu white yaks.
September 2025 in “Biomolecules” The skin microenvironment significantly affects hair growth and loss, offering potential treatment avenues.
November 2025 in “Cancers” Men with male pattern baldness may have a slightly higher risk of prostate cancer.
2 citations
,
July 2022 in “Frontiers in Medicine” The cause of Frontal fibrosing alopecia, a type of hair loss, is complex, likely involving immune responses and genetics, but is not fully understood.
46 citations
,
August 2020 in “International Journal of Genomics” Identifying specific genes helps improve goat breeding for better traits like growth and milk production.
45 citations
,
November 2024 in “International Journal of Molecular Sciences” Functional foods and nutrients like flavonoids, vitamin D, omega-3s, and probiotics can boost brain health and reduce stress.