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Anabolic androgenic steroids can increase cancer risk and disrupt hormones.

3α-androstanediol helps reduce age-related cognitive and mood declines in male rats, unlike testosterone.

Manipulating 5α-reductase type 2 can affect liver fat production and glucocorticoid effects.

PCOS is a common hormonal disorder in women, marked by high androgen levels and often seen in 20% of women via ultrasound.

Treatments for PCOS aim to reduce androgen levels and improve insulin sensitivity to lower cardiometabolic risk.

The document concludes that more multidisciplinary research is needed to understand and treat PCOS, a condition that significantly affects women's health and quality of life.

Intersex frogs have different brain gene activity related to sex and thyroid hormones.

Testosterone can slow hair growth in adult monkeys, but a blocker called RU 58841 can counteract this and potentially help hair regrow.

High AMH levels are linked to PCOS in women and may have a male equivalent with similar traits.

Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.

Hormone therapy for prostate cancer can increase heart risks, especially in men with heart conditions.

The animal models successfully simulated dry eye related to sex steroid deficiency.

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

Sex hormones may affect COVID-19 severity, with estrogen possibly reducing risk and testosterone potentially increasing it.

About 50% of 46, XY DSD cases lack a genetic diagnosis, but advanced sequencing methods improve detection.

Natural antioxidants like flavonoids and resveratrol may help prevent low testosterone in aging men.

Men with androgenetic alopecia have oilier and less hydrated scalps, especially in sensitive areas.

Baicalin may help reduce excessive male hormone levels in PCOS.

Testosterone helps prevent skin damage in males by acting through both estrogen and androgen pathways.

Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

Significant progress was made in understanding androgen excess disorders, but much is still unknown.

Probiotics and synbiotics might help manage hirsutism by improving insulin resistance.

Antiandrogens may help prevent or treat COVID-19 by blocking virus entry into cells.

Finasteride is more effective for hair loss in people with body hair.

GnRH analogue can help diagnose ovarian causes of high testosterone in postmenopausal women when scans don't show the cause.

Dihydrotestosterone (DHT) mainly affects nearby cells, doesn't significantly change prostate hormonal environment or cancer risk, and doesn't play a main role in causing hair loss or acne. More research is needed on its effects on heart health, sexual function, and bone health.

m6A deregulation plays a key role in PCOS and could lead to new treatments.

Nutritional supplements can help manage hair loss and promote hair growth by strengthening hair roots and countering harmful effects of pollution, smoking, and deficiencies in vitamins and minerals.

The secretome from mesenchymal stromal cells shows promise for improving facial nerve injury treatment.

Menopause can cause hair loss in women due to hormonal changes, affecting their well-being and quality of life.