January 2026 in “Journal of Dermatological Treatment” Oral finasteride may cause more sexual side effects than expected, possibly due to negative publicity and reporting bias.
9 citations
,
March 2023 in “GeroScience” April 2015 in “The FASEB Journal” Blocking androgens at birth reduces sexual motivation in male rats.
November 2023 in “Frontiers in Neuroendocrinology” Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.
January 2009 in “Reactions Weekly” A man had an allergic skin reaction on his penis from a hair loss medication, which improved after stopping the medication.
24 citations
,
March 2017 in “Journal of The European Academy of Dermatology and Venereology” Finasteride use linked to increased risk of sexual dysfunction, especially in younger people.
5 citations
,
May 2018 in “European journal of pharmacology” Fesoterodine is effective and safe for elderly patients with overactive bladder.
September 2025 in “Discover Chemistry.” Alpinia calcarata, Alpinia galanga, and Alpinia zerumbet have potential health benefits, including fiber, antimicrobial, antioxidant, and cardiovascular properties.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” Saw Palmetto, combined with Lycopene, L-Arginine, and Astaxanthin, improves male health by balancing hormones, reducing inflammation, and enhancing hair and urinary health without side effects.
23 citations
,
October 2008 in “Journal of medicinal chemistry” PF-998425 is a new, effective, and non-phototoxic treatment for skin conditions related to androgens.
60 citations
,
November 2009 in “General and Comparative Endocrinology” Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.
2 citations
,
March 2004 in “Reviews in Gynaecological Practice” Hormonal changes and psychological issues can cause sexual dysfunction in postmenopausal women. Behavioral therapy is recommended first, with hormone replacement helping some symptoms but not libido. Testosterone can improve libido, but its effects on overall sexual function are unclear. Emotional and relationship issues should be addressed before using medication, and the benefits and risks of testosterone supplementation should be considered.
September 2018 in “Translational Andrology and Urology” 39 citations
,
November 1990 in “The Journal of Steroid Biochemistry and Molecular Biology” Antiandrogens help treat hormone-related conditions in both men and women.
7 citations
,
January 2021 in “Food & Function” Chestnut flower extract may help reduce prostate cancer growth.
January 2022 in “Pharmaceutical Sciences Asia” Liposomes with butterfly pea extract and clove oil are stable and effective according to users.
2 citations
,
June 2009 in “PubMed” December 2025 in “Chemical Engineering Journal”
Olive leaves extract may help treat benign prostatic hyperplasia (BPH).
May 2023 in “Al-Mağallaẗ al-ʻirāqiyyaẗ li-l-ṣaydalaẗ” High doses of rosemary extract can harm the liver, kidneys, and reproductive organs in young rats.
January 2009 in “Xiandai huagong” Finasteride was successfully synthesized from Pregnadienolone acetate.
2 citations
,
February 2020 in “Rivista Urologia” Both terazosin and baclofen effectively reduce pain in young men with chronic testicular pain, with no difference in their effectiveness.
1 citations
,
October 2009 in “Current psychiatry” Choose treatments for sex offenders based on individual needs, using hormonal and nonhormonal options to reduce sexual drive.
5 citations
,
November 2015 in “Journal of Enzyme Inhibition and Medicinal Chemistry” Certain derivatives are more effective 5α-reductase type 2 inhibitors than finasteride.
11 citations
,
October 2015 in “Clinical and Experimental Dermatology” Sophora flavescens extract helps hair growth and treats hair loss.
May 2023 in “Journal of Applied Cosmetology” The Annurca apple supplement significantly improved hair growth in people with hair loss.
March 2016 in “The Journal of Urology” The discovery of 5α-reductase deficiency in guevedoces led to the development of important urologic medications.
January 2007 in “xPharm: The Comprehensive Pharmacology Reference”
1 citations
,
April 2006 in “Seminars in Reproductive Medicine” Androgen therapy might help some women with low libido, but it has risks and should be used carefully.