research Neuroactive steroid levels and psychiatric and andrological features in post-finasteride patients
Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.
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research Post-finasteride syndrome
Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.
research The androgen receptor gene polyglycine repeat polymorphism is associated with memory performance in healthy Chinese individuals
Certain gene variations are linked to better memory in healthy Chinese women.
research Brain allopregnanolone induces marked scratching behaviour in diet-induced atopic dermatitis mouse model
A brain-produced steroid causes increased scratching in mice with a skin condition similar to eczema.
research Reversal of alopecia areata, osteoporosis follow treatment with activation of Tgr5 in mice
Activating Tgr5 may help treat hair loss and bone loss.
research HHV-6 reactivations in immunocompetent patients with psychiatric disorders: visual hallucinations or possible interactions?
HHV-6 reactivation may be linked to psychiatric disorders and can improve with antiviral treatment.
research Over-expression of TSPO in the hippocampal CA1 area alleviates cognitive dysfunction caused by lipopolysaccharide in mice
Increasing TSPO in the brain may help improve memory problems.
research Ex vivo SIM-AFM measurements reveal the spatial correlation of stiffness and molecular distributions in 3D living tissue
Collagen makes skin stiff, and preservation methods greatly increase tissue stiffness.
research Mitochondria Dysfunction and Inflammation in Traumatic Brain Injury: Androgens to the Battlefront
Androgens like testosterone may help treat traumatic brain injury by reducing mitochondrial stress and inflammation.
research Biomembrane-Based Nanostructure- and Microstructure-Loaded Hydrogels for Promoting Chronic Wound Healing
Biomembrane-based hydrogels can effectively promote chronic wound healing.
research Injectable Biomimetic Gels for Biomedical Applications
Injectable biomimetic gels can help heal tissues and deliver drugs but need improvements in strength and delivery.
research Taurine, a non-proteinous essential amino acid for human body systems: an overview
Taurine is important for many body functions and its deficiency can cause health problems.
research 5α-reduced progestogens ameliorate mood-related behavioral pathology, neurotoxicity, and microgliosis associated with exposure to HIV-1 Tat
5α-reduced progestogens may reduce mood issues and brain damage linked to HIV-1 Tat.
research DIABETE E DOLORE: EFFETTO TERAPEUTICO DEI METABOLITI DEL TESTOSTERONE
Testosterone metabolites may help relieve diabetic nerve pain.
research Pericyte Plasticity in the Brain
research Recent advances in neuropeptide-related omics and gene editing: Spotlight on NPY and somatostatin and their roles in growth and food intake of fish
New tools show that in fish, NPY increases feeding and somatostatin decreases it.
research Frizzled Receptors in Development and Disease
Frizzled receptors are essential for various body development processes and maintaining certain body functions.
research Toll-like receptor-targeted anti-tumor therapies: Advances and challenges
TLR-targeted therapies show promise in cancer treatment by helping destroy tumors.
research Furnishing Wound Repair by the Subcutaneous Fascia
The subcutaneous fascia is key to fast wound healing and could improve treatments for chronic wounds and scarring.
research Non-viral delivery of the CRISPR/Cas system: DNAversusRNAversusRNP
RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.
research Extracellular vesicles as precision therapeutics for psychiatric conditions: targeting interactions among neuronal, glial, and immune networks
Extracellular vesicles could offer precise treatments for psychiatric conditions by targeting brain networks.
research Adenosine and Its Receptors in the Pathogenesis and Treatment of Inflammatory Skin Diseases
Adenosine receptors could be promising targets for treating inflammatory skin diseases like psoriasis.
research Sex steroid levels in corresponding cerebrospinal fluid and serum samples quantified by mass spectrometry in men
DHEA is the main sex steroid in cerebrospinal fluid, and testosterone in the fluid comes from the blood.
research Synthesis and Actions of 5α-Reduced Metabolites of Testosterone in the Nervous System
Testosterone and its metabolites affect brain functions and could help treat neurological disorders.
research Enhanced therapeutic effects of all-trans retinoic acid nanostructured lipid carrier composite gel drug delivery system for alopecia areata
The gel improves hair regrowth and reduces irritation in alopecia areata treatment.
research Probiotics: An Adjuvant therapy for D-Galactose induced Alzheimer's disease
L. plantarum MTCC 1325 may help improve memory and cognitive functions in Alzheimer's.
research Neonatal neurosteroid levels are determinant in shaping adult prepulse inhibition response to hippocampal allopregnanolone in rats
Neonatal neurosteroid levels affect adult brain function and behavior.
research Unraveling the complex role of MAPT-containing H1 and H2 haplotypes in neurodegenerative diseases
H1 increases risk for neurodegenerative diseases, while H2 offers protection but is linked to other disorders.
research Toll-like receptor 4 (TLR4): new insight immune and aging
TLR4 is important in aging-related diseases and could be a new treatment target.