research Epidermis-specific ablation of claudin-1 in adult mice demonstrates the essential role of a tight junction barrier in skin homeostasis
Claudin-1 is crucial for maintaining skin barrier and preventing inflammation.
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research Structure and Development of the Skin and Cutaneous Appendages
Understanding skin structure and development helps diagnose and treat skin disorders.
research Moth-Eaten Symptomatic Syphilitic Alopecia Associated with Human Immunodeficiency Virus—A Case Report
Hair loss in HIV patients should be tested for syphilis as well.
research Kids are not just little people: Pediatric versus adult dermatology approaches to skin diseases. Part I
Children's skin diseases and treatments differ from adults and require specific approaches.
research ALOPECIA AREATA-A CLINICAL ANALYSIS
Alopecia areata causes patchy hair loss due to unknown factors, affecting all ages and genders.
research Scientific Highlights from the Society for Investigative Dermatology 2010 Annual Meeting
The meeting highlighted major advances in skin research, including new findings on skin microbes, genetic links to skin diseases, and improved treatments for various conditions.
research Hot topics in pediatric dermatology
Covers common skin issues in kids, their diagnosis, treatment, and need for specialist care.
research Psychoneuroendocrinimmunodermatology
Stress can worsen some skin diseases like psoriasis and eczema.
research A Clinical Study on Alopecia
The study found that the most common symptom of alopecia was insomnia and the most used treatment was Shineung Yangjin Dan.
research Clinicoepidemiological profile, precipitating factors and severity indicators in alopecia areata in Manipur
Psychological stress is a major factor in the onset and severity of alopecia areata, with atopic individuals being more prone to develop it.
research Patient Profile and Treatment Characteristics of Adults and Adolescents Prescribed Ritlecitinib for Alopecia Areata in the USA
In the first 10 months following its FDA approval in June 2023, ritlecitinib was prescribed to a diverse group of patients aged ≥12 years with severe alopecia areata (AA) in the USA. This study analyzed data from 2,562 patients in cohort 1 and 381 in cohort 2, revealing that 62% were prescribed ritlecitinib by dermatologists, 59% were female, and 35% were adolescents. Approximately 24% had severe AA forms like alopecia totalis or universalis, 12% had other autoimmune disorders, 24% had atopic disorders, and 24% had mental health conditions. Before starting ritlecitinib, 27% had no prior AA treatments, while about one-third received systemic immunomodulators or injectable corticosteroids. In cohort 2, 77% experienced ≥50% scalp hair loss. The findings suggest ritlecitinib offers new opportunities for engaging patients in AA care, regardless of their treatment history or comorbidities.
research Upadacitinib in dermatologic therapy: Emerging evidence and expanding indications
Upadacitinib, a JAK1 inhibitor, has shown efficacy in treating various dermatological conditions, including atopic dermatitis and psoriasis, since its FDA approval for these uses. A comprehensive review of literature from 2015 to 2025 highlights its effectiveness, increasing real-world application, and cost-effectiveness compared to other treatments. The review includes systematic reviews, randomized controlled trials, and real-world studies, focusing on its use in cutaneous disorders while excluding non-dermatological indications and non-English articles. Upadacitinib's recent generic availability in India further supports its expanding role in dermatologic therapy.
research Associated comorbidities in pediatric patients with alopecia areata
Most kids with alopecia areata have other health issues, often allergies or skin conditions.
research The need for African dermatology guidelines—Steps towards equitable care
Africa needs its own dermatology guidelines to address unique skin challenges and improve care.
research The Genus Astragalus Species as an Emerging Source of Bioactive Phytochemicals: A Review of Dermatological and Cosmetic Applications
Astragalus plants may improve skin health and have anti-aging benefits.
research Common Skin Diseases and Metabolic Syndrome: A Proinflammatory Chemokine Perspective
Chronic skin diseases and metabolic syndrome are linked by shared inflammation pathways.
research Editorial: Exploring innovative therapies for rare inflammatory skin diseases
New therapies for rare skin diseases show promise but need more research.
research Implications of Dermatologic Disorders in Facial Cosmetic Surgery
Patients with skin disorders face higher risks of complications in facial cosmetic surgery.
research Exploration of Natural Adsorbents for Applications in Pollution-Reducing Cosmetic Formulations
Natural adsorbents in cosmetics can significantly reduce skin and hair pollution.
research Iron Deficiency in Immune-Mediated Inflammatory Skin Diseases: A Missing Link Between Systemic Inflammation, Immunometabolism, and Disease Burden
Iron deficiency worsens inflammatory skin diseases by disrupting iron balance and increasing inflammation.
research Geleneksel Derleme: Dermatoloji ve Kozmetolojide Eksozomlar
Exosomes show promise for treating skin conditions and improving cosmetic skin health.
research The brain–gut–skin axis in inflammatory and disfiguring skin diseases: mechanistic insights, clinical correlations, and therapeutic strategies
Skin diseases like acne and psoriasis are linked to stress, gut health, and inflammation, with new treatments focusing on gut and mind-body approaches.
research Presentations of Cutaneous Disease in Various Skin Pigmentations: Keratosis Pilaris
Recognizing keratosis pilaris in all skin tones helps diagnose related skin issues and reduce distress.
research Modulating the Gut–Skin Axis in Dermatological Diseases: Mechanisms and Clinical Applications of Probiotics, Prebiotics, Synbiotics, and Postbiotics
Certain probiotics can help improve skin conditions like atopic dermatitis, but more research is needed.
research Associated comorbidities in pediatric patients with alopecia areata
Children with alopecia areata often have related health issues like allergies, autoimmune diseases, or mental health conditions.
research Approach to Nail Pitting in Pediatric and Adolescent Patients: A Dermatology Perspective
Nail pitting in kids can be harmless or indicate other health issues, so thorough evaluation is crucial.
research Ruxolitinib: A novel molecule in the management of dermatological disorders
Ruxolitinib cream effectively treats skin conditions like atopic dermatitis and vitiligo with minimal side effects.
research Managing Skin Diseases that Flare During Pregnancy and in the Postpartum period: Part 2- Management & Safety Considerations
Managing skin diseases during pregnancy and postpartum requires careful consideration of treatment safety and dosing to protect both mother and baby.
research From Bald to Bold: Reversal of Alopecia Totalis in an Adolescent Using Dupilumab Monotherapy
Dupilumab helped a 13-year-old regrow hair after alopecia totalis.
research Feeding the skin: The emerging role of nutritional intervention in dermatological disorders
Nutrition plays a key role in managing skin disorders, with specific dietary changes helping improve conditions like acne, dermatitis, psoriasis, alopecia, and skin cancer.