Certain immune markers and vitamin levels could help diagnose alopecia areata.
71 citations
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May 2024 in “New England Journal of Medicine” Ruxolitinib may effectively treat APS-1 by reducing harmful immune responses.
3 citations
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November 2021 in “Journal of The American Academy of Dermatology” Androgenetic alopecia, a genetic disorder affecting up to 50% of adults, is caused by an excessive response to androgens leading to hair follicle shrinkage. Treatments include FDA-approved drugs, other therapies like low-dose oral minoxidil, and hair transplantation.
53 citations
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May 2011 in “Dermatologic therapy” Alopecia areata is a skin condition causing hair loss, and its exact cause is unknown, but it may involve biological mechanisms.
1 citations
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April 2017 in “Journal of Investigative Dermatology” Abatacept may help some people with alopecia areata regrow hair.
7 citations
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October 2010 in “Medical Hypotheses” Alopecia areata may involve stress-related changes affecting hormone receptors, leading to reduced cortisol production.
May 2025 in “Preprints.org” Unique microRNA patterns can help diagnose and treat severe alopecia areata.
20 citations
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October 2005 in “Archives of Dermatological Research” April 2018 in “Journal of Investigative Dermatology” Immune cells might contribute to hair loss caused by a specific mutation.
April 2018 in “Journal of Investigative Dermatology” IL-17C is important in inflammatory skin diseases and could be a target for treatment.
May 2026 in “International Journal of Homoeopathic Sciences” Individualized Homeopathic Medicine shows promise for treating alopecia with lasting hair regrowth.
2 citations
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January 2015 in “Elsevier eBooks” Epigenetic changes contribute to autoimmune skin diseases.
April 2020 in “IP Indian journal of clinical and experimental dermatology” Many children with alopecia areata also have other autoimmune diseases.
June 2015 in “Annals of the Rheumatic Diseases” Managing multiple autoimmune diseases in one patient is very challenging.
November 2025 in “Scholarly Commons (Embry–Riddle Aeronautical University)” Urban air pollution worsens hair loss in alopecia areata by increasing immune response.
October 2025 in “International Journal of Molecular Sciences” Early intervention in patch-type alopecia may prevent progression to more severe forms by targeting immune pathways and preserving keratin.
January 2019 in “Przegląd Dermatologiczny” An 87-year-old woman was diagnosed with type 3 autoimmune polyendocrine syndrome and had multiple autoimmune issues.
10 citations
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November 2023 in “Science Immunology” Super-enhancers control CD25 expression in specific cell types, affecting immune function.
January 2026 in “Dermatology Reports” Upadacitinib improved symptoms and hair regrowth in a teen with multiple autoimmune conditions.
April 2010 in “Cancer Research” Basal cell carcinomas may use IDO to protect themselves from the immune system.
1 citations
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August 2019 in “Journal of Investigative Dermatology” PRDX5 enzyme may contribute to alopecia areata by affecting oxidative stress and autoimmunity.
38 citations
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July 1989 in “Archives of dermatological research” Testosterone causes hair loss in AGA mice, which are good for testing baldness treatments, and both minoxidil and cyproterone acetate can prevent this hair loss.
11 citations
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March 2013 in “Gene” A certain genetic variation in the IL1A gene may lower the risk of a hair loss condition in Chinese people.
May 2020 in “Lithuanian University of Health Sciences” Alopecia areata is an autoimmune disease causing hair loss, with treatments often ineffective but new options are being researched.
3 citations
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August 2024 in “Frontiers in Immunology” Targeting specific biomarkers and immune signals is more effective and safer for treating inflammatory skin diseases.
4 citations
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November 2018 in “JAAD case reports” Alopecia areata can sometimes appear as a straight line of hair loss instead of round patches.
April 2026 in “Frontiers in Medicine” Farudodstat may help prevent hair loss in alopecia areata by stopping immune attacks on hair follicles.
11 citations
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July 2008 in “International Journal of Dermatology” Greying hairs may be protected from alopecia areata.
14 citations
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September 2021 in “Journal of Inflammation Research” Alopecia areata patients, especially women with nail issues or atopic diseases, are at higher risk for other autoimmune diseases.
June 2020 in “Zenodo (CERN European Organization for Nuclear Research)” Children with frequent severe infections and low antibodies should be checked for immune deficiencies.