research ¿Novedad o prudencia? El delicado equilibrio en la actualización farmacológica
New drugs face challenges due to limited evidence, and safety updates are advised for some existing medications.
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research Discovery of New Drug Therapies Based on the Study of Adverse Reactions
Side effects of drugs can lead to the discovery of new treatments.
research Immune Cell-Targeting Biologics for Alopecia Areata: A New Paradigm in Precision Medicine
research Preparing regenerative therapies for clinical application: proposals for responsible translation
The document suggests a need for collaboration, better evidence, and a responsible framework to safely and effectively advance regenerative therapies to clinical use.
research Fully automated chip-based nanoelectrospray ionization-mass spectrometry as an effective tool for rapid and high-throughput screening of 5α-reductase inhibitors
research Can you Create Low Molecular Weight Pharmacologically Active Substances and Maintain Mental Function Normal? Yes, we Can
New substances were created that improve health and may treat dementia, osteoporosis, and cancer.
research Pangenome and genome variation analyses of pigs unveil genomic facets for their adaptation and agronomic characteristics
Pangenome analysis reveals key genes for pig adaptation and traits, aiding genetic improvement.
research Drug Discovery Insights from a Computational QSAR Study on Alpha-Reductase Inhibitors and Layered Double Hydroxides Electrocatalysts
Computational techniques can improve drug development for treating certain conditions.
research Discovery of clinically approved drugs capable of inhibiting SARS-CoV-2 in vitro infection using a phenotypic screening strategy and network-analysis to predict their potential to treat covid-19
Four drugs were found that could potentially treat COVID-19 by inhibiting the virus in lab tests.
research One of These Things Is Not Like the Others: The Idea of Precedence in Health Technology Assessment and Coverage Decisions
The conclusion is that formalizing how past decisions influence current health technology assessments could improve the credibility and defense of coverage decisions.
research 501 Next-generation in vitro testing: microfluidic models for aging, wound healing, and oral tissue analysis in safety, efficacy, and permeation studies
Microfluidic models improve testing for aging, wound healing, and oral tissue, reducing animal testing.
research Virtual Bioequivalence Assessment of Ritlecitinib Capsules with Incorporation of Observed Clinical Variability Using a Physiologically Based Pharmacokinetic Model
50-mg ritlecitinib capsules are bioequivalent to 100-mg capsules.
research Mechanical engineering of hair follicle regeneration by in situ bioprinting
3D bioprinting can effectively regenerate hair follicles and skin tissue in wounds.
research Efficient integration of human skin single-cell RNA sequencing data
A comprehensive human skin cell atlas was created to better understand skin biology and disease.
research Nano-Enabled CRISPR-Cas Gene Editing for Cancer Therapeutics
Nanotechnology improves CRISPR-Cas9 delivery for cancer treatment, but challenges remain.
research Advancing immunotherapy using biomaterials to control tissue, cellular, and molecular level immune signaling in skin
research Problem-Based Learning Tools: Problem-Based Learning Pedagogy and Strategies Are Used to Implement Project-Based Science
Problem-based learning in a biology class improved students' thinking and problem-solving skills.
research LB1011 Cost and access changes with TNFa inhibitor biosimilars entering the market
Biosimilars lower costs but don't significantly improve access.
research MicroRNAs in skin tissue engineering
MicroRNAs could improve skin tissue engineering by regulating cells and changing the skin's bioactive environment.
research Microneedles: A Promising Therapeutic Strategy for Next-Generation Drug Delivery, Diagnosis and Biosensing
Microneedles offer a painless, precise, and versatile method for drug delivery and disease treatment.
research Screening of synthetic and natural product databases: Identification of novel androgens and antiandrogens
Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.
research Bioactive Molecules for Skin Repair and Regeneration: Progress and Perspectives
Bioactive molecules show promise for improving skin repair and regeneration by overcoming current challenges with further research.
research Development of Pneumatic Dual-Cell Stacking Implanter
The new device can implant cell mixtures more effectively for hair loss treatment and is easier for operators to use.
research Biodegradation of Marine Pollutants by Microorganisms: A Bibliometric Analysis
Interest in using microorganisms to reduce ocean pollution is growing.
research Advancing mitochondrial therapeutics: Synthesis and pharmacological evaluation of pyrazole-based inhibitors targeting the mitochondrial pyruvate carrier
New pyrazole-based inhibitors show promise for treating metabolic diseases and other conditions.
research In vitro bioassays for androgens and their diagnostic applications
In vitro bioassays are better than traditional methods for measuring androgen activity but aren't ready for routine use yet.
research Protein Immobilization on Bacterial Cellulose for Biomedical Application
Bacterial cellulose is a promising material for biomedical uses but needs improvements in antimicrobial properties and degradation rate.
research Study on botulinum toxin in dermatology from 2000 to 2023: A CiteSpace ‐based bibliometric analyses
Botulinum toxin use in dermatology is evolving, with new research trends emerging.
research Deep Insight of Design, Mechanism, and Cancer Theranostic Strategy of Nanozymes
Nanozymes show promise for effective and safe cancer treatment.
research Bio-Enhanced Hair Restoration
Bio-enhanced hair restoration improves hair growth.