The agouti gene may help understand and treat obesity.
April 2024 in “International journal of molecular sciences” Dermal factors are crucial in regulating melanin production in skin.
April 2023 in “Journal of Investigative Dermatology” Sweating can potentially be controlled through olfactory receptors, with β-ionone playing a key role, and responses may vary between genders.
April 2026 in “Diagnostics” Skin changes in obesity can indicate metabolic issues but aren't reliable for assessing risk or monitoring treatment.
38 citations
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April 2016 in “The Journal of Pathology” Alkaline ceramidase 1 is crucial for healthy skin and energy balance.
Fat tissue can potentially treat a common form of hair loss called androgenic alopecia.
MFN2 mutations cause mitochondrial problems, unusual fat distribution, and low leptin despite high body fat.
1 citations
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February 2022 in “Experimental Dermatology” Certain proteins are found at higher levels in balding areas compared to non-balding areas, suggesting a link to hair loss. This could be useful for diagnosing and treating hair loss.
PPARβ/δ helps yaks adapt to high altitudes by regulating lipid metabolism in their coats.
Higher levels of certain proteins in hair loss areas may help understand and treat hair loss.
218 citations
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May 2014 in “Experimental Dermatology” Skin fat cells help with skin balance, hair growth, and healing wounds.
49 citations
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July 2000 in “Journal of Histochemistry & Cytochemistry” POMC-derived peptides are important for skin functions like immune response and stress management.
2 citations
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August 2024 in “JID Innovations” AD-derived keratinocytes effectively mimic inflammation in atopic dermatitis.
March 2023 in “Здобутки клінічної і експериментальної медицини” Low vitamin D in overweight teens is linked to higher leptin and lower adiponectin, affecting metabolism.
November 2022 in “Journal of Investigative Dermatology” Mitochondrial stress can lead to atopic dermatitis.
June 2026 in “Journal of Investigative Dermatology” Aging weakens sweat glands due to reduced support from immune cells, but treatments may help restore function.
November 2022 in “Journal of Investigative Dermatology” Deleting MPZL3 increases skin oil production and reduces body fat.
November 2023 in “Journal of Investigative Dermatology” Adipose stem cell exosomes may effectively treat atopic dermatitis by reducing inflammation and improving skin health.
18 citations
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March 2015 in “Journal of Investigative Dermatology” Silencing certain circadian clock genes increases skin pigmentation.
1 citations
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April 2016 in “Journal of lipid research” Lipin-1 is important for skin cell differentiation and skin barrier function.
63 citations
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January 2021 in “Adipocyte” Adipose tissue-derived exosomes help regulate metabolism and may aid in disease treatment.
16 citations
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February 2013 in “Molecular Medicine Reports” CD34+ cells from fat tissue help form hair follicles and blood vessels in skin.
January 2026 in “Journal of Cosmetic Dermatology” Menopause reduces skin fat, but treatments like magnolol and PLLA-SCA can help restore skin health.
19 citations
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August 2019 in “Journal of Cellular Biochemistry” ADSCs help protect skin from UV damage and aging.
November 2025 in “Journal of Investigative Dermatology” Dark skin has stronger barriers and structure due to specific gene activity.
December 2017 in “Journal of Cosmetic Dermatology” Researchers found certain genes are overactive and others are underactive in men with early balding, which could help create new treatments.
September 2025 in “Stem Cell Research & Therapy” TAZ boosts fat cell formation in goat stem cells by activating a specific signaling pathway.
January 2010 in “Experimental Dermatology” Adiponectin may help hair grow based on lab tests.
February 2025 in “International Journal of Molecular Sciences” Altered lipid pathways in diabetic women may cause premature greying.
February 2023 in “Clinical, Cosmetic and Investigational Dermatology” Higher leptin and lower vitamin D levels may contribute to male pattern baldness.