60 citations
,
May 2014 in “British Journal of Dermatology” Caffeine affects hair growth and health differently in men and women.
35 citations
,
January 2018 in “Skin pharmacology and physiology” Nanoemulsion creams with certain enhancers can greatly increase caffeine delivery through skin.
35 citations
,
February 2002 in “Journal of Radiological Protection” Caffeine reduces radiation skin damage but doesn't affect tumor treatment.
33 citations
,
September 2006 in “International Journal of Cosmetic Science” Caffeine improves male skin's barrier function.
26 citations
,
December 2009 in “Laser Physics” Caffeine from shampoo penetrates hair follicles quickly and stays for at least 24 hours.
24 citations
,
February 2007 in “Laser Physics Letters” Caffeine shampoo penetrates hair follicles deeply and stays for up to 48 hours.
21 citations
,
September 1966 in “Toxicology and Applied Pharmacology” Caffeine becomes more toxic in rats when food intake is reduced by over 50%.
17 citations
,
October 2015 in “The Journal of Physiology” Combining progesterone with caffeine worsens breathing issues in newborns.
15 citations
,
October 2020 in “European journal of pharmaceutics and biopharmaceutics” Caffeine penetrates skin quickly through open hair follicles, but less through closed ones, with levels becoming equal after 22 hours.
15 citations
,
June 1996 in “Journal of Pharmacy and Pharmacology” Caffeine levels in hair and blood can indicate liver health.
10 citations
,
July 2021 in “European journal of pharmaceutics and biopharmaceutics” Nanoparticles sized between 470 and 750 nm are best for delivering substances like caffeine into hair follicles for absorption.
7 citations
,
October 2024 in “AAPS PharmSciTech” CA-SLN-Ngel significantly reduces cellulite more effectively than regular caffeine gel.
7 citations
,
January 2020 in “Skin Pharmacology and Physiology” Standard nail varnish effectively prevents follicular penetration of certain substances.
4 citations
,
February 2022 in “Journal of Pharmaceutical and Biomedical Analysis” The conclusion is that a new method can measure caffeine and drugs in hair, finding caffeine abusers have 70 times more caffeine than normal, with a proposed cut-off value for abuse.
4 citations
,
September 1999 in “Journal of Clinical Forensic Medicine” Caffeine in hair might help identify people, but it's not always reliable.
2 citations
,
January 2022 in “Materials today: proceedings” Caffeine may be good for hair growth and skin care because it binds well with keratin.
1 citations
,
July 2023 in “Cosmetics” The new shampoo effectively delivers caffeine to hair follicles to help keep hair, especially as people age.
1 citations
,
February 2020 in “PubMed” The topical solution improved hair density and appearance in men with androgenetic alopecia.
January 2026 in “AAPS PharmSciTech” Liposomal formulations with caffeine and cafestol enhance skin penetration effectively.
January 2026 in “British Journal of Dermatology” Caffeine and DMG increase calcium influx in hair follicle cells without being toxic.
October 2025 in “Journal of Drugs in Dermatology” Topical caffeine can help with hair growth and reduce hair loss safely.
September 2025 in “Journal of Drug Delivery Science and Technology” Vitamin D3-coated nanoparticles effectively deliver caffeine for alopecia treatment with minimal side effects.
August 2025 in “Journal of Cosmetic Dermatology” The shampoo with DMG-Na and caffeine effectively reduces hair loss and improves hair density in men.
TrichoSol™ effectively stabilizes various hair treatment ingredients for different durations.
December 2024 in “http://isrctn.com/” MpowerTM may improve hair growth and satisfaction more than plain minoxidil, with mild side effects.
TrichoFoam™ is a stable option for personalized hair loss treatment with most ingredients remaining effective for 90-180 days.
January 2024 in “Indonesian Journal of Pharmaceutical Education” The Caffein Herbasome® cream is stable and suitable for skin use.
Red clover and caffeine both promote hair growth, but combining them doesn't enhance the effect.
September 2023 in “Journal of The American Academy of Dermatology” Caffeine may help hair grow better.
Cinchona succirubra extract with caffeine reduces hair loss and strengthens hair.