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GlossaryCannabidiol

non-psychoactive compound in cannabis with potential therapeutic effects

Cannabidiol, commonly known as CBD, is a non-psychoactive compound found in cannabis plants, including hemp and marijuana. It is widely studied for its potential therapeutic effects, such as reducing inflammation, alleviating pain, and managing anxiety, without causing the "high" associated with THC (tetrahydrocannabinol).

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The Phytocannabinoid (–)-Cannabidiol Operates as a Complex, Differential Modulator of Human Hair Growth: Anti-Inflammatory Submicromolar Versus Hair Growth Inhibitory Micromolar Effects

research The Phytocannabinoid (–)-Cannabidiol Operates as a Complex, Differential Modulator of Human Hair Growth: Anti-Inflammatory Submicromolar versus Hair Growth Inhibitory Micromolar Effects

15 citations , July 2019 in “Journal of Investigative Dermatology”

CBD can either reduce inflammation and not affect hair growth at low levels or inhibit hair growth at high levels.

Efficacy and Tolerability of a Shampoo Containing Broad-Spectrum Cannabidiol in the Treatment of Scalp Inflammation in Patients with Mild to Moderate Scalp Psoriasis or Seborrheic Dermatitis

research Efficacy and Tolerability of a Shampoo Containing Broad-Spectrum Cannabidiol in the Treatment of Scalp Inflammation in Patients with Mild to Moderate Scalp Psoriasis or Seborrheic Dermatitis

14 citations , January 2020 in “Skin appendage disorders”

A shampoo with cannabidiol can significantly reduce scalp inflammation and symptoms in people with mild to moderate psoriasis or seborrheic dermatitis.

research Hair Regrowth with Cannabidiol (CBD)-rich Hemp Extract – A Case Series

7 citations , April 2021 in “Cannabis”

CBD-rich hemp oil can significantly increase hair regrowth in people with common hair loss, with no reported side effects.

research Unravelling a novel role for cannabidivarin in the modulation of subventricular zone postnatal neurogenesis

7 citations , October 2023 in “European Journal of Pharmacology”

Cannabidivarin (CBDV) may help brain cell growth and survival through the TRPV1 receptor.

research 263 (-)-cannabidiol differentially influences hair growth

3 citations , September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

CBD can either promote or inhibit hair growth depending on the concentration used.

research The Therapeutic Potential of Cannabidiol in Skin Conditions

1 citations , November 2025 in “Journal of Cosmetic Dermatology”

CBD might help with skin issues, but more research is needed.

research Skin applications of cannabidiol: sources, effects, delivery systems, marketed formulations and safety

1 citations , March 2023 in “Phytochemistry Reviews”

CBD may improve skin and hair health, but its effective use and safety need more research.

research Regulatory Effect of Cannabidiol (CBD) on Decreased β-Catenin Expression in Alopecia Models by Testosterone and PMA Treatment in Dermal Papilla Cells

1 citations , June 2021 in “Journal of pharmacopuncture”

CBD may help restore hair growth-related protein levels in alopecia caused by hormones or other factors.

research 477 How Cannabidiol Supports Hair Growth: From Epigenetics to the Scalp Microbiome

November 2025 in “Journal of Investigative Dermatology”

CBD can help hair grow by supporting scalp health and reducing inflammation.

research Cannabidiol in Skin Health: A Comprehensive Review of Topical Applications in Dermatology and Cosmetic Science

August 2025 in “Biomolecules”

CBD may help with skin and hair issues, but more research is needed.

research Chitosan Nanoparticulate System Loaded with Cannabidiol: A Topical Formulation for Potential Alopecia Management

February 2025 in “Processes”

A new CBD topical formulation may effectively and safely treat alopecia.

research 44389 Cannabidiol in Sunscreen: A Survey of Current Peer-Reviewed Evidence

September 2023 in “Journal of the American Academy of Dermatology”

CBD might help protect skin from UV rays in sunscreen, but more research is needed.

research Unravelling a novel role for Cannabidivarin in the modulation of subventricular zone postnatal neurogenesis

May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

Cannabidivarin (CBDV) helps new brain cells grow and develop in a specific brain area through a certain receptor.

research Case Study of Hair Regrowth with Topical Cannabidiol (CBD)

1 citations , July 2021 in “Hair transplant forum international”

Daily use of CBD-rich hemp oil significantly increased hair growth in people with hair loss.

research Current state of knowledge on the use of cannabidiol (CBD) in various medical conditions

June 2023 in “Journal of Education, Health and Sport”

CBD is effective for certain epilepsy conditions, shows promise for other health issues, but needs more research for safety and effectiveness.

research Targeting Cutaneous Cannabinoid Signaling in Inflammation - A “High”-way to Heal?

28 citations , January 2017 in “EBioMedicine”

Enhancing cannabinoid signaling may help treat skin inflammation.

research Cannabinoids for skin diseases and hair regrowth

20 citations , August 2021 in “Journal of Cosmetic Dermatology”

Cannabinoids might help with skin diseases and hair growth, but more research is needed.

Can We Teach Old Drugs New Tricks? Repurposing Neuropharmacological Drugs for Inflammatory Skin Diseases

research Can we teach old drugs new tricks?—Repurposing of neuropharmacological drugs for inflammatory skin diseases

15 citations , June 2019 in “Experimental Dermatology”

Old neuropharmacological drugs might be effective for treating inflammatory skin diseases.

research Dermal drug delivery with ethosomes: therapeutic potential

14 citations , July 2007 in “Therapy”

Ethosomes can effectively deliver drugs deep into the skin, improving treatment for various skin conditions.

research Endocannabinoid activation and polycystic ovary syndrome: A systematic review

5 citations , January 2020 in “Research journal of pharmacy and technology”

CBD may help reduce stress and pain in women with PCOS.

research Development and Characterization of Dual-Loaded Niosomal Ion-Sensitive In Situ Gel for Ocular Delivery

4 citations , December 2024 in “Gels”

The gel effectively delivers drugs to the eye, fights bacteria, and protects against oxidative stress.

research In vitro, ex vivo, and clinical evaluation of anti‐aging gel containing EPA and CBD

3 citations , June 2023 in “Journal of cosmetic dermatology”

The gel with CBD and EPA reduced wrinkles, improved skin hydration and elasticity, and had strong anti-aging effects.

research Cannabinoid Compounds as a Pharmacotherapeutic Option for the Treatment of Non-Cancer Skin Diseases

3 citations , December 2022 in “Cells”

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

research A cannabinoid Hairy‐Tale: Hair loss or hair gain?

2 citations , October 2022 in “Journal of cosmetic dermatology”

CBD may increase hair growth, but the right concentration is crucial and more research is needed.

research Natural products for male androgenetic alopecia

2 citations , January 2022 in “Dermatologic Therapy”

Natural products like saw palmetto, caffeine, melatonin, marine extracts, rosemary oil, procyanidin, pumpkin seed oil, and cannabidiol oil could potentially treat male hair loss.

research The Role of Cannabinoids in the Treatment of Skin Diseases: A Review of Mechanisms of Action and Clinical Evidence

1 citations , November 2025 in “Journal of Education Health and Sport”

Cannabinoids like CBD may help treat skin diseases by reducing inflammation and infections.

research Treatment Advances for Acne Vulgaris: The Scientific Role of Cannabinoids

1 citations , February 2024 in “Cosmetics”

Cannabidiol shows promise as an effective treatment for acne.

research Cannabinoids and Their Receptors in Skin Diseases

1 citations , November 2023 in “International journal of molecular sciences”

Cannabinoids might help treat skin problems but more research is needed to be sure.

research Drug Repurposing in Dermatology: Molecular Biology and Omics Approach

1 citations , August 2020 in “IntechOpen eBooks”

Old drugs like finasteride and spironolactone are being successfully used for hair loss and skin conditions, and many other drugs show promise for new uses in dermatology.

research A Comprehensive Review of Acne Treatments: Unpacking the Chemical Structures and Effective Bioactive Compounds

February 2026 in “Health Science Reports”

Understanding acne medication chemistry helps doctors treat acne better.