research From basic biology to engineered therapies: the keratinocyte stem cell playbook
Keratinocyte stem cells are crucial for skin renewal and have potential in wound healing and tissue regeneration.
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research Bioregenerative Applications of the Human Mesenchymal Stem Cell- Derived Secretome: Part-II
The mesenchymal stem cell secretome may effectively treat various diseases as an alternative to traditional stem cell therapies.
research KIF18B is a cell-type specific regulator of spindle orientation in the epidermis
KIF18B is important for correctly positioning cell division machinery in skin cells, affecting hair follicle development.
research 877 Integration of magnetic tweezers and traction force microscopy for exploring the mechanobiology of keratinocyte cell-cell and cell-matrix anchoring junctions
The conclusion is that a new method combining magnetic tweezers and traction force microscopy may help understand skin cell interactions and diseases.
research Shushing down the epigenetic landscape towards stem cell differentiation
The document concludes that pig iPSCs show promise for transplant therapies and the field is advancing in controlling cell behavior for biology and medicine.
research The promise and challenges of cell therapy for psoriasis*
Cell therapy shows promise for treating severe psoriasis but needs more research to confirm safety and effectiveness.
research T helper 17 cell/regulatory T-cell imbalance in hidradenitis suppurativa/acne inversa: the link to hair follicle dissection, obesity, smoking and autoimmune comorbidities
An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.
research Dietary supplementation with Essential-oils-cobalt for improving growth performance, meat quality and skin cell capacity of goats
Essential-oils-cobalt improves goat growth and product quality.
research Engineering Cell‐Derived Matrices: From 3D Models to Advanced Personalized Therapies
3D cell-derived matrices improve tissue regeneration and disease modeling.
research Skin cell-derived extracellular vesicles: a promising therapeutic strategy for cutaneous injury
Skin cell-derived vesicles can help heal skin injuries effectively.
research Integrated single-cell chromatin and transcriptomic analyses of peripheral immune cells in patients with alopecia areata
Early intervention with JAK inhibitors may prevent alopecia areata progression.
research Dental cell type atlas reveals stem and differentiated cell types in mouse and human teeth
The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.
research Stem Cell-Based Tissue Engineering for the Treatment of Burn Wounds: A Systematic Review of Preclinical Studies
Stem cell treatments may improve burn wound healing.
research Responses of hair follicle–associated structures to loss of planar cell polarity signaling
Loss of Fz6 disrupts hair follicle and associated structures' orientation.
research Immune cell regulation of the hair cycle
Immune cells affect hair growth and could lead to new hair loss treatments.
research State-dependent signaling by Cav1.2 regulates hair follicle stem cell function
Cav1.2 affects hair growth and could be a target for hair loss treatments.
research Essential Role of Polarity Protein Par3 for Epidermal Homeostasis through Regulation of Barrier Function, Keratinocyte Differentiation, and Stem Cell Maintenance
The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.
research Conventional and novel stem cell based therapies for androgenic alopecia
Stem cell technologies and regenerative medicine, including platelet-rich plasma, show promise for hair restoration in treating hair loss, but more research is needed.
research Protective effects of finasteride against testosterone-induced calcium oxalate crystallization and crystal-cell adhesion
Finasteride helps prevent kidney stones, but side effects need more research.
research Tooth, hair and claw: Comparing epithelial stem cell niches of ectodermal appendages
The conclusion is that teeth, hair, and claws have similar stem cell niches, which are important for growth and repair, and more research is needed on their regulation and potential markers.
research Highly Upregulated Lhx2 in the Foxn1−/− Nude Mouse Phenotype Reflects a Dysregulated and Expanded Epidermal Stem Cell Niche
The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.
research “Two-Cell Assemblage” Assay: A Simple in vitro Method for Screening Hair Growth-Promoting Compounds
The "Two-Cell Assemblage" assay is a new, simple method to identify substances that may promote hair growth.
research The role of B cell-activating factor system in autoimmune diseases: mechanisms, disease implications, and therapeutic advances
BAFF-targeted therapies can reduce autoimmune disease activity, but more research is needed for precise treatments.
research The Anti-Aging Effects of Adipose-Derived Mesenchymal Stem Cell Exosomes on Skin and Their Potential for Personalized Skincare Applications
Adipose-derived stem cell exosomes and AI can improve personalized skincare by offering anti-aging benefits and precise product customization.
research Hair-follicle associated pluripotent (HAP)-cell-sheet implantation enhanced wound healing in diabetic db/db mice
HAP-cell-sheets improved wound healing in diabetic mice.
research Stem cell activity shapes the pleiotropic effects of IFN-γ and TGF-β in autoimmune diseases, infections, and cancer, and drives autoimmune flares and remissions
Stem cell activity influences autoimmune disease outcomes by affecting immune responses and tissue regeneration.
research 1379 Cell of origin contributes to the melanoma diversity
Different types of stem cells in the skin contribute to the variety of melanoma forms.
research Mesenchymal stem cell‐derived exosomes for organ development and cell‐free therapy
MSC-Exos can aid organ development and offer therapeutic benefits for various conditions.
research From a stem-cell–centered to a niche-centered view: the core role of collagen networks in hair loss and hair follicle miniaturization
Collagen networks play a key role in hair loss and follicle miniaturization.
research IL-15 in T-Cell Responses and Immunopathogenesis
IL-15 is key for T cell function and could help improve treatments for immune-related diseases.