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Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.

A new keratin, hK6irs1, is found in all layers of the hair follicle's inner root sheath.

Early diagnosis and a strict gluten-free diet are crucial for children with celiac disease to improve symptoms.

α-mangostin nanoparticles improved acne with minimal irritation.

The same genetic mutation in Sjögren-Larsson syndrome can lead to different levels of severity, suggesting other factors influence the symptoms.

Hand and forearm transplants can be successful long-term, but they come with challenges like rejection and side effects from immunosuppression.

Removing certain brain receptors in mice worsens seizure severity and response to treatment during hormone withdrawal.

The UD-PrOZA program successfully diagnosed 18% of adult patients with rare diseases, often using genetic testing.

COVID-19 may worsen Parkinson's disease by affecting certain brain proteins.

Lupeol shows promise for hair growth but needs better absorption and safety testing.

Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.

Astragalus plants may improve skin health and have anti-aging benefits.

Cytarabine can cause multiple organ toxicities, especially neurotoxicity, but better research methods are needed to fully understand and predict these effects.

New-onset fibromyalgia after COVID-19 is poorly understood and needs more research.

HHV-6 reactivation may be linked to psychiatric disorders and can improve with antiviral treatment.

Celiac disease requires more than just a gluten-free diet for effective management.

COVID-19 vaccination may be linked to MIS-C in children, highlighting the need for quick diagnosis and treatment.

Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.

Neuropathic pruritus is a commonly overlooked and wrongly diagnosed type of chronic itching that is hard to treat.

TGFα gene mutation in mice causes abnormal skin, wavy hair, curly whiskers, and sometimes eye inflammation.

Adipose-derived stem cells are promising for tissue and organ repair due to their easy access and versatility.

Both estrogens and androgens are important for health in both males and females.

Allogenic ASCs and ECM transplants are safe and effective for tissue regeneration.

Designing effective fluorescence microscopy experiments requires careful consideration of hardware, biological models, and imaging agents.

Organoid technology helps create mini-organs for studying diseases and testing drugs.

Skin inflammation can worsen intestinal inflammation and colitis.

Alkaline Ceramidase 1 prevents early hair loss in mice by keeping hair follicle stem cells balanced.

Isotretinoin can cause serious birth defects and needs careful use, especially in pregnant women.

Neurosteroids and benzodiazepines reduce neuron excitability, with lasting effects on inhibitory neurons.