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Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.

Understanding skin stem cells and their regulation is key to improving skin healing and treating disorders.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

3D bioprinted lung cancer models in a mouse-like structure offer a better way to study radiation effects without using live animals.

Thymic stromal lymphopoietin (TSLP) promotes hair growth, especially after skin injury.

Extracellular vesicles could revolutionize skincare by improving skin repair and anti-aging, but face regulatory and cost challenges.

Human pluripotent stem cells could be used to make platelets for medical use, but safety, effectiveness, and cost issues need to be resolved.

Corneal cells can potentially revert to stem cells, aiding in repair and regeneration.

A protein called desmoglein 3 is important for keeping hair follicle stem cells inactive and helps in their regeneration.

High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.

Combining hyperthermia with natural compounds and conventional treatments improves cancer therapy effectiveness and reduces side effects.

Compound 7p shows strong potential as an anticancer agent.

Advancements in regenerative science and longevity research can improve healthspans, but must be balanced with ethics and safety.

Exosome therapy could be a promising new way to treat hair loss.

Sulforaphane from broccoli may help treat certain cancers, hormone issues, and hair loss.

Adipose-derived stem cells can help repair and improve eye tissues and appearance.

Baby teeth stem cells can potentially grow organs and treat diseases.

Key signals like Wnt and β-catenin are crucial for skin and hair development, with potential for treating skin disorders.

Understanding EGFR's role in skin is crucial for better treatments and managing side effects.

Biopolymeric composites need advanced properties for better use in medicine and healing.

Keratin 15 expression in skin cells is regulated by two mechanisms involving PKC/AP-1 and FOXM1.

Plet-1 protein helps hair follicle cells move and stick to tissues.

Stem cell therapy helps heal burn wounds faster in animals.

RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

Stem cells could potentially rebuild missing structures in wounds, improving facial skin replacement techniques.

Natural products show promise for treating diseases but need more research to understand and use them effectively.

Human skin xenografting could improve our understanding of skin development, renewal, and healing.

Forsythiae Fructus has anti-inflammatory, antibacterial, and antiviral properties, with differences between unripe and ripe forms important for clinical use.