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GlossaryCollagen Deposition

process of collagen buildup in tissues for structural support

Collagen deposition refers to the process by which collagen, a structural protein, is produced and accumulated in tissues. This process is crucial for wound healing and maintaining the strength and elasticity of skin, tendons, and other connective tissues. In the context of hair and alopecia, excessive or insufficient collagen deposition can affect hair follicle health and potentially contribute to hair loss conditions.

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research Antiaging effects of equol: A unique antiandrogenic isoflavone metabolite and its influence in stimulating collagen deposition in human dermal monolayer fibroblasts

2 citations , March 2005 in “Journal of the American Academy of Dermatology”

Equol may help with antiaging and skin health by boosting collagen and blocking certain hormones.

research Accelerative action of topical piperonylic acid on mice full thickness wound by modulating inflammation and collagen deposition

3 citations , October 2021 in “PLoS ONE”

Piperonylic acid speeds up wound healing by reducing inflammation and boosting collagen.

research Biological Macromolecule Hydrogel Based on Recombinant Type I Collagen/Chitosan Scaffold to Accelerate Full-Thickness Healing of Skin Wounds

12 citations , September 2023 in “Polymers”

The hydrogel speeds up skin wound healing effectively.

research Mesenchymal Stem Cells Pretreated with Collagen Promote Skin Wound-Healing

6 citations , May 2023 in “International journal of molecular sciences”

Collagen-enhanced mesenchymal stem cells significantly improve skin wound healing.

research Fermented rice bran extract delays skin aging by increasing the synthesis of collagen and elastin

November 2025 in “Frontiers in Pharmacology”

Fermented rice bran extract helps delay skin aging by boosting collagen and elastin.

research Cell-free adipose extract inhibits hypertrophic scar formation through collagen remodeling and antiangiogenesis

January 2025 in “Open Medicine”

High-concentration cell-free adipose extract reduces scar formation and improves scar appearance.

research Injectable Polypeptide‐Protein Hydrogels for Promoting Infected Wound Healing

262 citations , May 2020 in “Advanced Functional Materials”

The hydrogel promotes faster healing of infected wounds by enhancing tissue regeneration and preventing infection.

research Development of a Chitosan Nanofibrillar Scaffold for Skin Repair and Regeneration

162 citations , July 2011 in “Biomacromolecules”

Chitosan nanofiber scaffolds improve skin healing and are promising for wound treatment.

research Thymosin β4 promotes angiogenesis, wound healing, and hair follicle development

118 citations , December 2003 in “Mechanisms of Ageing and Development”

Thymosin β4 helps heal wounds, grow hair, and improve blood vessel formation.

research Nanotechnology Approaches in Chronic Wound Healing

110 citations , April 2020 in “Advances in Wound Care”

Nanotechnology shows promise for better chronic wound healing but needs more research.

research Biocomposite nanofiber matrices to support ECM remodeling by human dermal progenitors and enhanced wound closure

87 citations , August 2017 in “Scientific Reports”

The nanofiber scaffolds improved skin wound healing by supporting cell growth and tissue repair.

research Animal models for the study of fetal tissue repair

69 citations , September 1991 in “Journal of Surgical Research”

Understanding how fetal wounds heal could help improve healing in adults.

research Two-Dimensional Biodegradable Black Phosphorus Nanosheets Promote Large Full-Thickness Wound Healing through In Situ Regeneration Therapy

57 citations , January 2024 in “ACS Nano”

Black phosphorus nanosheets help heal large wounds by reducing inflammation and promoting tissue regeneration.

research Efficacy of Carbazole Alkaloids, Essential Oil and Extract of Murraya koenigii in Enhancing Subcutaneous Wound Healing in Rats

57 citations , December 2012 in “Molecules”

Murraya koenigii extract and mahanimbicine significantly speed up wound healing in rats.

research A compositionally synergistic approach for the development of a multifunctional bilayer scaffold with antibacterial property for infected and chronic wounds

54 citations , May 2021 in “Chemical Engineering Journal”

The developed scaffold effectively treats chronic wounds by promoting healing and preventing infection.

research Skin wounds in the MRL/MPJ mouse heal with scar

51 citations , January 2006 in “Wound Repair and Regeneration”

MRL/MpJ mice's skin wounds heal with scars, unlike their ear wounds which can regenerate.

research Electrospun radially oriented berberine-PHBV nanofiber dressing patches for accelerating diabetic wound healing

49 citations , January 2024 in “Regenerative Biomaterials”

The new nanofiber patch speeds up diabetic wound healing and improves healing quality.

Enhanced Cutaneous Wound Healing by Functional Injectable Thermo-Sensitive Chitosan-Based Hydrogel Encapsulated Human Umbilical Cord-Mesenchymal Stem Cells

research Enhanced cutaneous wound healing by functional injectable thermo-sensitive chitosan-based hydrogel encapsulated human umbilical cord-mesenchymal stem cells

48 citations , July 2019 in “International Journal of Biological Macromolecules”

A new hydrogel with stem cells from human umbilical cords improves skin wound healing and reduces inflammation.

research Design of a Multifunctional Biomaterial Inspired by Ancient Chinese Medicine for Hair Regeneration in Burned Skin

45 citations , March 2020 in “ACS Applied Materials & Interfaces”

The new biomaterial inspired by ancient Chinese medicine effectively promotes hair growth and heals wounds in burned skin.

research Androgenetic alopecia in males: a histopathological and ultrastructural study

42 citations , June 2009 in “Journal of Cosmetic Dermatology”

Hair loss in males involves inflammation, collagen buildup, and follicle damage, with severity increasing with age and baldness duration.

research Microneedle Array Patch Made of Kangfuxin/Chitosan/Fucoidan Complex Enables Full-Thickness Wound Healing

40 citations , January 2022 in “Frontiers in Chemistry”

The patch speeds up deep wound healing.

Adipose Mesenchymal Stem Cells Combined with Platelet-Rich Plasma Accelerate Diabetic Wound Healing by Modulating the Notch Pathway

research Adipose mesenchymal stem cells combined with platelet-rich plasma accelerate diabetic wound healing by modulating the Notch pathway

39 citations , July 2021 in “Stem Cell Research & Therapy”

Using fat stem cells and blood cell-rich plasma together improves healing in diabetic wounds by affecting cell signaling.

research The Role of Extracellular Vesicles in Cutaneous Remodeling and Hair Follicle Dynamics

38 citations , June 2019 in “International Journal of Molecular Sciences”

Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.

research Interleukin-25-Mediated-IL-17RB Upregulation Promotes Cutaneous Wound Healing in Diabetic Mice by Improving Endothelial Cell Functions

34 citations , January 2022 in “Frontiers in Immunology”

IL-25 helps heal diabetic wounds by improving blood vessel and skin cell functions.

Electrospun Fibrous Sponge via Short Fiber for Mimicking 3D Extracellular Matrix

research Electrospun fibrous sponge via short fiber for mimicking 3D ECM

34 citations , May 2021 in “Journal of Nanobiotechnology”

The 3D electrospun fibrous sponge is promising for tissue repair and healing diabetic wounds.

research Fabrication of Electrospun Probiotic Functionalized Nanocomposite Scaffolds for Infection Control and Dermal Burn Healing in a Mice Model

34 citations , September 2019 in “ACS Biomaterials Science & Engineering”

Probiotic nanoscaffolds significantly improved burn healing and infection control in mice.

research Effect of P144® (Anti-TGF-β) in an “In Vivo” Human Hypertrophic Scar Model in Nude Mice

32 citations , December 2015 in “PloS one”

P144® improves hypertrophic scars by reducing size and thickness and increasing elasticity.

research Novel ECM Patch Combines Poly(vinyl alcohol), Human Fibroblast-Derived Matrix, and Mesenchymal Stem Cells for Advanced Wound Healing

28 citations , June 2020 in “ACS Biomaterials Science & Engineering”

The new ECM patch greatly improves wound healing and tissue regeneration.

research Photoaging Skin Therapy with PRP and ADSC: A Comparative Study

27 citations , July 2020 in “Stem Cells International”

ADSC therapy is more effective and safer for treating photoaged skin than PRP.

research Differential cutaneous wound healing in thermally injured MRL/MPJ mice

26 citations , July 2007 in “Wound Repair and Regeneration”

MRL/MpJ mice heal burns slower with more scarring and less tissue regeneration than BALB/c mice.