research Polycystic Ovary Syndrome and the Potential for Nanomaterial-Based Drug Delivery in Therapy of This Disease
Nanomaterials could improve PCOS treatment by delivering drugs more effectively with fewer side effects.
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780-810 / 1000+ resultsresearch Recent Insights in Multi‐Target Drugs in Pharmacology and Medicinal Chemistry
Multitarget drugs are needed to better treat complex diseases.
research Genomic prediction and genome-wide association studies of morphological traits and distraction index in Korean Sapsaree dogs
Genomic prediction can improve breeding strategies for Korean Sapsaree dogs.
research Bio-Nanovesicle-Based Approaches for Hair and Skin Regeneration: An Updated Concise Review
Bio-nanovesicles could improve hair and skin regeneration by delivering important molecules to repair and heal.
research In Silico Promoter Motif Analysis of Human Fertility-Related Genes
The study found potential new DNA patterns in fertility genes, but further testing is needed.
research Increasing the solubility of minoxidil using a mixture of 1-propanol and water by the shake flask method: experimental measurements, thermodynamic analyses, and mathematical modeling
research Two-Stage Machine Learning-Based GWAS for Wool Traits in Central Anatolian Merino Sheep
Machine learning can effectively identify genes to improve wool quality in sheep.
research Therapeutic Efficacy and Promise of Human Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles in Aging and Age-Related Disorders
Human umbilical cord stem cell vesicles may help treat aging and related diseases.
research Repurposed Drugs: Current Trends in Drug Discovery
Drug repurposing speeds up development, cuts costs, and uses known safe drugs, but faces challenges like regulations and patents.
research Investigation the role of SIRT3, SIRT7, NFATC1, and PDL-1 genes in androgenetic alopecia
SIRT3 and SIRT7 genes may play a role in hair loss.
research A Profuse Pipeline of Promising Options
The document concludes that significant investment in agricultural innovation is necessary to achieve global food security and nutrition.
research Biomaterials Mimicking Mechanobiology: A Specific Design for a Specific Biological Application
Polymers can be designed to mimic natural cell environments for medical uses.
research Hair growth-promoting activity of ginsenoside Rf from Panax ginseng C.A. Meyer, an industrial crop-derived functional material
Ginsenoside Rf from Panax ginseng promotes hair growth and could be a natural alternative for treating hair loss.
research Stimuli-responsive hydrogels for radiation-induced skin injury: from passive barriers to autonomous drug delivery systems
Advanced hydrogels can autonomously deliver drugs to treat radiation skin injuries, but challenges remain for clinical use.
research RNA modifications: molecular orchestrators of wound healing
RNA modifications help heal wounds and could lead to new treatments.
research Hedgehog signaling reprograms hair follicle niche fibroblasts to a hyper-activated state
Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.
research A KRT71 Loss-of-Function Variant Results in Inner Root Sheath Dysplasia and Recessive Congenital Hypotrichosis of Hereford Cattle
A specific genetic change in the KRT71 gene causes a hair loss condition in Hereford cattle.
research The JAK/STAT signaling pathway: from bench to clinic
The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
research Activating an adaptive immune response from a hydrogel scaffold imparts regenerative wound healing
Hydrogel scaffolds can help wounds heal better and grow hair.
research The Skin Microbiome: Current Landscape and Future Opportunities
The skin microbiome is crucial for skin health, and more research is needed to explore its role and potential treatments.
research Immunological challenges associated with artificial skin grafts: available solutions and stem cells in future design of synthetic skin
Artificial skin grafts face immune rejection, but stem cells may improve future designs.
research The RpoS Gatekeeper in Borrelia burgdorferi: An Invariant Regulatory Scheme That Promotes Spirochete Persistence in Reservoir Hosts and Niche Diversity
RpoS helps Borrelia burgdorferi survive in hosts and adapt to different environments.
research The importance of the neuro‐immuno‐cutaneous system on human skin equivalent design
Human skin models are essential for studying skin's sensory, immune, and nervous system interactions.
research Amino acid–derived defense metabolites from plants: A potential source to facilitate novel antimicrobial development
Plant-derived amino acids can help develop new antimicrobial drugs.
research Metal-Chelation-Assisted Deposition of Polydopamine on Human Hair: A Ready-to-Use Eumelanin-Based Hair Dyeing Methodology
Polydopamine is a safe, effective, and permanent hair dye that turns gray hair black in one hour.
research Medicinal Chemistry of Drugs with N-Oxide Functionalities
N-oxides are important in medicine for improving drug properties and targeting.
research Autosomal Recessive Hypotrichosis with Woolly Hair Caused by a Mutation in the Keratin 25 Gene Expressed in Hair Follicles
A mutation in the KRT25 gene causes a rare hair disorder with thin, woolly hair.
research Functional Enhancers As Master Regulators of Tissue-Specific Gene Regulation and Cancer Development.
Enhancers and super-enhancers are key in controlling specific gene activity and can play a role in cancer development.
research Significance of stress keratin expression in normal and diseased epithelia
Stress keratins are expressed less in diseased skin and are linked to differentiation, inflammation, and immunity.
research From Diospyros kaki L. (Persimmon) Phytochemical Profile and Health Impact to New Product Perspectives and Waste Valorization
Persimmons offer health benefits and can be used in new products and sustainable applications.