1 citations
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January 2016 in “Medicinski glasnik Specijalne bolnice za bolesti štitaste žlezde i bolesti metabolizma” Most 46XX CAH patients have female identity, but a few identify as male and may need treatment and surgery.
27 citations
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April 2011 in “Folia Histochemica et Cytobiologica” DHT deficiency can disrupt cell connections in rat testes, possibly affecting fertility.
April 2020 in “Journal of the Endocrine Society” Early diagnosis of PSIS can lead to normal height with growth hormone and testosterone treatment.
November 2022 in “Journal of the Endocrine Society” A 13-year-old girl's masculine symptoms improved after surgery for a rare adrenal tumor that produced male hormones.
21 citations
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December 2015 in “Development Growth & Differentiation” DHT is crucial for urethral formation, and its disruption can affect masculinization and lead to hypospadias.
11 citations
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June 2005 in “Postgraduate Medical Journal” Some infants temporarily grow scrotal hair, which usually disappears on its own without any health issues.
7 citations
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January 2022 in “Case Reports in Endocrinology” Ovarian hyperthecosis can cause symptoms even with normal testosterone levels, and surgery can improve these symptoms.
October 2023 in “IJEM case reports” A 15-year-old girl with no menstrual period was diagnosed with a genetic condition that makes her body unable to respond to male hormones, leading to female characteristics despite having male genetic makeup.
1 citations
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October 2024 in “BMJ Case Reports” Fertility-preserving surgery can help women with early-stage Sertoli-Leydig cell tumors conceive naturally.
June 2025 in “V F Snegirev Archives of Obstetrics and Gynecology” A six-year-old girl has early signs of puberty, needs no treatment, but requires regular check-ups for future health risks.
3 citations
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June 2016 in “Gynecological Endocrinology” Doctors used a special blood sampling technique to diagnose a woman's rare ovarian tumor that was producing male hormones.
February 2023 in “Frontiers in Endocrinology” Too much male hormone in mothers can negatively affect the sexual behavior of both male and female baby mice.
1 citations
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April 2022 in “AACE clinical case reports” A 36-year-old person with a female appearance but male chromosomes was diagnosed with a rare enzyme deficiency affecting sexual development.
16 citations
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January 2019 in “LGBT health” Transgender women can still get testicular cancer, so proper screening is important.
January 2024 in “Wiadomości Lekarskie” Male sperm disorders significantly contribute to infertility.
June 2020 in “AACE clinical case reports” A woman's severe male hormone excess was caused by a small, hard-to-find ovarian tumor.
5 citations
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January 2012 in “International journal of trichology” A 2-year-old boy had no hair and unusual organ placement, and it's unclear if it's genetic or coincidental.
51 citations
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August 2012 in “Differentiation” Mouse genital development depends on male or female hormones for specific features.
5 citations
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June 2008 in “Acta Cirurgica Brasileira” Finasteride causes sperm production decrease in Mesocricetus auratus.
8 citations
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January 2017 in “Fertility and Sterility” Urologic diseases and treatments in older men can negatively affect fertility, and doctors should talk to patients about this.
August 2004 in “Veterinary Dermatology” Adult-onset hair loss in Chesapeake Bay retrievers may be linked to abnormal adrenal hormone production.
15 citations
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May 2010 in “Pediatrics in Review” Delayed puberty often runs in families, can affect growth, and may need hormone treatment.
November 2022 in “Journal of the Endocrine Society” Always consider xanthomatous hypophysitis before deciding on pituitary surgery.
163 citations
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November 1976 in “Annals of Internal Medicine” Sickle cell anemia causes hormone issues and delayed puberty due to testicular failure.
February 2022 in “Obstetrics and gynaecology cases - reviews” PCOS can cause unusual symptoms like late puberty and enlarged clitoris, making diagnosis difficult.
13 citations
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July 2018 in “General and comparative endocrinology” Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.
December 2023 in “International journal of molecular sciences” Chromosomal differences affect how muscle cells respond to testosterone.
June 2026 in “Reproductive Biology”
September 2024 in “Medicine theory and practice” A young girl's hyperandrogenism was caused by an adrenocortical adenoma, diagnosed and treated through detailed evaluations.
March 2026 in “JCEM Case Reports” Surgery removed ovarian tumors, normalizing testosterone and improving symptoms.