137 citations
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January 2006 in “Frontiers in bioscience” CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.
132 citations
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June 2016 in “Cell and Tissue Research” The right cells and signals can potentially lead to scarless wound healing, with a mix of natural and external wound healing controllers possibly being the best way to achieve this.
128 citations
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October 2011 in “Development” Activating a protein called β-catenin in adult skin can make it behave like young skin, potentially helping with skin aging and hair loss.
122 citations
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April 2020 in “American Journal Of Pathology” Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.
96 citations
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December 2018 in “Immunity” Targeting TGFβ can improve skin immunity in older people.
91 citations
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August 2024 in “Acta Pharmaceutica Sinica B” Microneedles can improve skin disease treatment by delivering drugs directly through the skin.
46 citations
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July 2022 in “Frontiers in Oncology” Cold atmospheric plasma is a promising and safe treatment for various skin conditions.
42 citations
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December 2011 in “The journal of immunology/The Journal of immunology” RANKL causes lymph nodes to grow by making certain cells multiply.
38 citations
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February 2021 in “Journal of Investigative Dermatology” Aging slows wound healing due to weaker cells and immune response.
37 citations
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January 2022 in “Frontiers in Genetics” Aging reduces dermal sheath cells, affecting youthful skin appearance.
32 citations
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June 2021 in “Frontiers in Pharmacology” The hydrogel speeds up burn wound healing and promotes tissue regeneration.
32 citations
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July 2017 in “Molecular diagnosis & therapy” MicroRNA-21 could help diagnose and treat skin fibrosis.
29 citations
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December 2004 in “Developmental biology” cDermo-1 causes dense skin, feathers, and scales in chickens.
28 citations
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April 2023 in “Stem cell research & therapy” Tiny vesicles from stem cells could be a new treatment for healing wounds.
27 citations
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August 2003 in “Anais Brasileiros de Dermatologia” Neuropeptides affect skin inflammation, repair, and hair growth, with potential for therapy.
26 citations
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March 2018 in “Experimental Dermatology” Prolactin may influence skin glands and could be a target for treating acne and skin aging.
26 citations
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April 1998 in “Journal of Investigative Dermatology” Sunscreens with higher SPF and UVA filters offer the best protection against skin aging from UVA rays.
22 citations
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June 2010 in “Experimental Dermatology” Lower MC2R expression may contribute to alopecia areata.
18 citations
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January 2020 in “Indian Dermatology Online Journal” Platelet-rich plasma shows potential for hair loss and skin rejuvenation but needs more research for widespread use.
16 citations
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February 2013 in “Molecular Medicine Reports” CD34+ cells from fat tissue help form hair follicles and blood vessels in skin.
13 citations
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December 2001 in “Journal of Investigative Dermatology” Overexpressing ornithine decarboxylase and v-Ha-ras in keratinocytes leads to invasiveness and malignancy.
9 citations
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January 2018 in “Medical research archives” Low-intensity light therapy is effective for skin healing, reducing inflammation, and treating various skin conditions.
9 citations
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November 2017 in “Frontiers in Pharmacology” Shengfu oil speeds up wound healing by reducing inflammation and promoting tissue repair.
6 citations
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October 2024 in “Frontiers in Bioengineering and Biotechnology” A special hydrogel helps stem cells heal wounds better by boosting growth factors.
6 citations
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December 2023 in “Journal of Clinical Medicine” Abnormal growth factor metabolism may link psoriasis and metabolic syndrome, and obesity can affect psoriasis treatment effectiveness.
6 citations
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June 2013 in “Toxicological Research” Topical Valproate is safe for human skin and unlikely to cause irritation.
2 citations
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November 2025 in “Pharmaceutics” Cell-mediated drug delivery systems improve skin disease treatment by using living cells for precise, prolonged, and less toxic therapy.
1 citations
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November 2024 in “Revista Foco” PRP effectively and safely reduces wrinkles and rejuvenates skin.
1 citations
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June 2023 in “Cells” Exosomes could be a promising way to help repair skin and treat skin disorders.
1 citations
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April 2022 in “Regenerative Therapy” Activating the GDNF-GFRα1-RET signaling pathway could potentially promote skin and limb regeneration in humans and could be used to treat hair loss and promote wound healing.