research NDA Submission of Vepdegestrant (ARV-471) to U.S. FDA: The Beginning of a New Era of PROTAC Degraders
Vepdegestrant may become the first FDA-approved PROTAC degrader, marking a new era in drug development.
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690-720 / 1000+ resultsresearch Double-wavelength laser scanning microphotometer (DWLSM) for in-vitro hair shaft and surrounding tissue imaging
The DWLSM provides detailed imaging of hair shafts and follicles with high accuracy.
research Lupus erythematosus-like lesions in a carrier of X-linked chronic granulomatous disease: A case report and personal considerations
A woman with X-linked chronic granulomatous disease developed lupus-like skin lesions, improved with treatment, suggesting a unique skin condition in carriers.
research Current Development of Mesenchymal Stem Cell-Derived Extracellular Vesicles
MSC-derived EVs show promise for therapy, but production and understanding need improvement.
research Interactive analysis of single-cell trajectories in 3D space with Cell Journey
Cell Journey is a tool for better 3D visualization of cell changes over time.
research The Phenotypic and Genotypic Spectra of Ichthyosis With Confetti Plus Novel Genetic Variation in the 3′ End ofKRT10
Ichthyosis with confetti is a genetic skin disorder with consistent ectodermal malformations and various KRT10 gene mutations.
research Transverse Leukonychia and Beau Lines Following COVID-19 Vaccination
COVID-19 vaccination may cause temporary nail changes, but they're not serious.
research Central Centrifugal Cicatricial Alopecia Associated With PDL1 Loss and Increased Expression of Caspase 3: A Case Series
CCCA may involve the PD1/PDL1 pathway and increased caspase 3, leading to permanent hair loss.
research Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1+/– mice
Targeting ornithine decarboxylase can help prevent skin cancer.
research Lentivirus-Mediated Expression of VEGF165 in Rat Hair Follicle Stem Cells
Rat hair follicle stem cells can be used to improve blood vessel growth in engineered skin.
research Metformin/dopamine derived bioactive carbon dots accelerate bacteria‐infected wound healing
Metformin/dopamine-derived carbon dots help heal bacteria-infected wounds faster.
research Solution Copolymerizations of N‐Vinyl‐2‐Pyrrolidone with Acrylic Acid, Methacrylic Acid and Vinyl Acetate for Applications in Hair Cosmetics
These polymers can improve hair texture and reduce water loss in hair cosmetics.
research A Scandinavian case of skin fragility, alopecia and cardiomyopathy caused byDSPmutations
A child with skin and heart issues had rare genetic mutations affecting skin and heart cell cohesion.
research Evaluation of the Tolerability of Hedgehog Pathway Inhibitors in the Treatment of Advanced Basal Cell Carcinoma: A Narrative Review of Treatment Strategies
Hedgehog pathway inhibitors for advanced basal cell carcinoma can cause side effects, but managing them helps maintain treatment.
research CD10 for the distinct differential diagnosis of basal cell carcinoma and benign tumours of cutaneous appendages originating from hair follicle.
CD10 helps distinguish between basal cell carcinoma and benign hair follicle tumors.
research Normal-pressure-prepared chitosan carbonate liquid dressing: Spontaneous transformation into a pure chitosan water-resistant film and enhanced wound repair
The new chitosan dressing heals wounds better and faster than current products.
research The Tumor Suppressor Actions of the Vitamin D Receptor in Skin
Vitamin D receptor helps prevent skin tumors.
research The VEGF +405 G>C 5' untranslated region polymorphism and risk of PCOS: a study in the South Indian Women
The VEGF +405G allele may increase the risk of PCOS in South Indian women.
research New-Onset Gastrointestinal Polyposis
A 60-year-old man with Cronkhite-Canada syndrome improved with treatment, but the condition has a high mortality rate and a risk of colorectal cancer.
research 51794 Compounded Solution to Personalize Alopecia Management
The compounded topical solution is safe, stable, and effective for personalized alopecia treatment.
research Análise de marcadores de células tronco e progenitores das células de polpa dentária e de vibrissas de camundongos C57BL6.
Dental pulp and vibrissa cells in mice show different stem cell markers, suggesting potential for regenerative medicine.
research Cervical spine imaging and treatment outcomes in scalp dysesthesia: A retrospective cohort study
Degenerative changes in the lower cervical spine are common in patients with abnormal scalp sensations, with some improvement seen using pain medication and physical therapy.
research Deletion of vitamin D receptor with calcium sensing receptor in keratinocytes promotes epidermal tumorigenesis by limiting dna repair and oxidative stress response genes
Deleting vitamin D and calcium receptors in skin cells increases skin cancer risk by reducing DNA repair and stress response.
research The role of ultrasound and Doppler analysis in the diagnosis of polycystic ovary syndrome
Ultrasound and Doppler analysis are valuable tools for diagnosing and understanding polycystic ovary syndrome.
research Elevated body mass index, statin use, and cholecystectomy are associated with vulvar lichen sclerosus: A retrospective, case-control study
Being overweight, having gallbladder removal surgery, and taking cholesterol-lowering drugs are linked to a higher chance of getting vulvar lichen sclerosus.
research Manifestaciones dermatológicas por Covid-19 y su aporte en la comprensión de la enfermedad
Skin symptoms appear in up to 20% of Covid-19 cases.
research The Tumor Suppressor Actions of the Vitamin D Receptor in Skin
Vitamin D receptor helps prevent skin tumors.
research A New Tool to Maximize Donor Harvesting With Safer Closure
The cross beam laser is a useful tool for safely measuring scalp stretchiness to improve hair transplant results.
research Optimized skin optical clearing for optical coherence tomography monitoring of encapsulated drug delivery through the hair follicles
A PEG-400/oleic acid mixture best improves drug delivery monitoring through hair follicles.
research Deucravacitinib in dermatology: current indication and existing off-label data
Deucravacitinib effectively treats psoriasis and may help with other skin conditions.