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The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Chronic stress can reduce skin pigmentation.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Honokiol helps protect skin from damage and aging caused by cigarette smoke.

Rare adrenal cancers that secrete androgens or estrogens have a poor prognosis and are treated primarily with surgery.

ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

Serum steroid profiling, especially 11-deoxycortisol, helps distinguish between adrenocortical carcinoma and adenoma, considering sex and functional status.

m⁶A methylation is crucial for proper wound healing and tissue repair.

Hirsutism is mainly caused by high androgen levels or sensitivity, with PCOS being the most common cause.

Rodent models of PCOS show some hormone changes similar to humans, but also have key differences.

Liquorice has medicinal benefits, including antioxidant, anti-inflammatory, antimicrobial, antiulcer, and antiviral effects.

11β-Hydroxylase inhibitors help prevent seizures in mice by boosting natural neurosteroid production.

Extracellular vesicles can both worsen and help treat age-related diseases and are useful for early diagnosis.

Hair steroid measurement is an effective method to diagnose and monitor CAH in developing countries.

The retinoid receptor antagonist effectively disrupts vitamin A-related development in embryos.

Oral dutasteride is effective and safe for treating frontal fibrosing alopecia.

PPAR-γ helps control skin oil glands and inflammation, and its disruption can cause hair loss diseases.

PRC2 is essential for maintaining intestinal cell balance and aiding regeneration after damage.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

Baicalin may help reduce excessive male hormone levels in PCOS.

TCDD disrupts skin stem cells, causing skin issues like chloracne.

Air pollution harms skin health and can worsen skin diseases.

Targeting regulatory T cells may help treat age-related diseases.

Ent-kaurane-type diterpenoids from Isodonis Herba may promote hair growth by boosting cell proliferation.

Removing Lrig1-positive cells in mice leads to temporary loss of sebaceous glands.